Cafenstrole (Ref: CH 900)
Last updated: 23/08/2023
(Not known by any other names)
Cafenstrole is a triazole rice herbicide. It has a low water solubility and is semi-volatile. It is not persistence in soil systems. It has a low level of toxicity to mammals. It shows a moderate level of toxicity to most aquatic species and birds. It is not particularly toxic to honeybees.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
Used for the pre- and early post-emergence control of annual weeds, particularly grassy weeds in paddy fields
Crabgrass; Barnyardgrass; Flatsedge; Annual bluegrass; Manila grass
Paddy rice
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Current
1997, Japan
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
None
C₁₆H₂₂N₄O₃S
CCN(CC)C(=O)N1C=NC(=N1)S(=O)(=O)C2=C(C=C(C=C2C)C)C
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HFEJHAAIJZXXRE-UHFFFAOYSA-N
InChI=1S/C16H22N4O3S/c1-6-19(7-2)16(21)20-10-17-15(18-20)24(22,23)14-12(4)8-11(3)9-13(14)5/h8-10H,6-7H2,1-5H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
cafenstrole
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Herbicide
Triazole herbicide; Amide herbicide
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Synthetic
Good residual activity and high selectivity. IInhibition of VLCFA (inhibition of cell division).
125306-83-4
603-054-9
None allocated
Not listed
195429
No data found
350.44
N,N-diethyl-3-(2,4,6-trimethylbenzene-1-sulfonyl)-1H-1,2,4-triazole-1-carboxamide
N,N-diethyl-3-mesitylsulfonyl-1H-1,2,4-triazole-1-carboxamide
N,N-diethyl-3-[(2,4,6-trimethylphenyl)sulfonyl]-1H-1,2,4-triazole-1-carboxamide
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K3
15
Not applicable
Not applicable
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Colourless crystalline solid
2.5
at 25 °C
Low
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115
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1.62 X 1003
Calculated
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3.21
High
Likely to be soluble
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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Based on chemical group
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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1.30
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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5.3 X 10-05
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
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8
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-persistent
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General literature: DT₅₀ 8 days (upland), 7 days (paddy fields)
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Soil adsorption and mobility
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Cannot be calculated
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None
Terrestrial ecotoxicology
> 5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
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> 2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Anas platyrhynchos
Low
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> 1000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
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1.2
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Cyprinus carpio
Moderate
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> 500
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Daphnia magna
Low
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HUMAN HEALTH AND PROTECTION
High (class III)
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> 5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
1.97
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat 14 days
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Acute percutaneous LD₅₀ > 2000 mg kg⁻¹
Rats
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EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No dta
 
No further information available
No information available
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Not listed (Not listed)
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cafenstrole
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Record last updated:
23/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242