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benzyl benzoate
** benzoic acid phenylmethyl ester ** benzyl phenylformate ** benzoic acid benzyl ester ** benzylbenzenecarboxylate ** benzylis benzoas ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
Further data may be found in the PPDB

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for benzyl benzoate

Description: Most common use is for the treatment of "Sweet Itch" in horses. Is also sometiems used to treat mites responsible for causing scabies.

Availability status: Current

Introduction & key dates: -

Examples of species treated: Horses

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C14H12O2
Canonical SMILES C1=CC=C(C=C1)COC(=O)C2=CC=CC=C2
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) SESFRYSPDFLNCH-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H2
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Veterinary substance type Antiparasitic
Other constituent type Solvent
Substance group Bridged diphenyl
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Attacks the nervous system of mites
Molecular targets -
CAS RN 120-51-4
EC number 204-402-9
CIPAC number -
US EPA chemical code 009501
PubChem CID 2345
ATCvet Code QP53AX11
Therapeutic Class Antiparasitic products, insecticides & repellents: Ecoparasiticides, insecticides & repellents
Controlled Drug? No
Regulation 37/2010 MRL Classification Allowed substance (Table 1: All food producing species)
Molecular mass (g mol-1) 212.25
PIN (Preferred Identification Name) benzyl benzoate
IUPAC name benzyl benzoate
CAS name phenylmethyl benzoate
Other status information -
Relevant Environmental Water Quality Standards -
Physical state Colourless to pale yellow oily liquid with pleasant aromatic odour
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Product Manufacturer Authorisation Route UK Legal Class
Example products using this active Killitch 25% w/v cutaneous emulsion Carr Day and Martin Ltd UK National authorisation Authorised veterinary medicine for general sale (AVM - GSL)
Savlon Veterinary Antiseptic concentrate Schering-Plough Ltd No UK authorisation for use Not applicable
Bensyleasi Easivet No UK authorisation for use Not applicable
Formulation and application details Veterinary formulations are usually emulsions for topical application. Non-agricultural formulations include foams and powders.


ENVIRONMENTAL FATE

for benzyl benzoate

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 15.4 V3 - @ 25 DegC Low
Solubility - In organic solvents at 20oC (mg l-1) Miscible B5 - Ether -
Miscible B5 - Ethanol -
Miscible B5 - Methanol -
Miscible B5 - Acetone -
Melting point (oC) 18 B4 -
Boiling point (oC) 323 E3 -
Degradation point (oC) - - -
Flashpoint (oC) 158 E3 - (closed cup) -
Octanol-water partition coefficient at pH 7, 20oC P 9.33 X 1003 Calculated -
Log P 3.97 V3 High
Bulk density (g ml-1)/Specific gravity 1.12 B4 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 20oC (mPa) 29.86 CA2 Highly volatile
Henry's law constant at 25oC (Pa m3 mol-1) 0.284 V3 Moderately volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index - - -
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -
Refractive Index 1.5681 Q3 -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
Soil degradation (days) (aerobic) DT50 (typical) - - -
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note: -
Manure DT50 (days) - - -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
benzoic acid - Humans - -
benzyl alcohol - Humans - -
hippuric acid - Humans - -


ECOTOXICOLOGY

for benzyl benzoate

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) - - -
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 2800 B4 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 2000 F3 Colinus virginianus Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 4.6 E3 Unknown species Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) - - -
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms Acute LC50 (mg kg-1) - - -
Chronic NOEC (mg kg-1) - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for benzyl benzoate

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class Low (class I) - -
Mammals - Acute oral LD50 (mg kg-1) > 2800 B4 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 B3 Rat -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints Intraperitoneal LD50 > 500 mg kg-1 V3 Mouse -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Routes Public No unacceptable risks identified
Occupational May be absorbed through the skin
Elimination route and rate Metabolised and excreted mainly in the urine Q3 -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A0; B0; C0; D0; E0

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues May cause nausea and vomiting
In large doses may cause skin blistering, crusting & scaling
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Combustible
IMDG Transport Code is usually 9
Incompatible with alkalis and oxidising agents
CLP classification 2013 -
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R22
Xi - Irritant: R36, R38
EC Safety Classification Click here to view information omn the EU safety phrases S2, S46, S56
WHO Classification NL - Not listed
UN Number 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for benzyl benzoate

Language Name
English benzyl benzoate
French -
German -
Danish -
Italian -
Spanish -
Greek -
Slovenian -
Polish -
Swedish -
Hungarian -
Dutch -

Record last updated: Saturday 26 May 2018
Contact: aeru@herts.ac.uk