Fluvalinate |
Last updated: 26/08/2024 |
(Not known by any other names) |
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A topical pyrethroid insecticide used to control a broad range of animal pests but now considered to be obsolete | |
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Considered obsolete but may be available in some countries | |
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1980, first reported | |
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Used to control common insect pests such as mites, ticks and fleas | |
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Cattle |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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Fluvalinate is a chiral molecule. Technical fluvalinate material is an isomeric mixture of the R- and S-isomers. However, commerical products now only use the R-isomer (tau-fluvalinate) | |
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C₂₆H₂₂ClF₃N₂O₃ | |
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CC(C)C(C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl | |
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No data | |
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INISTDXBRIBGOC-UHFFFAOYSA-N | |
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InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3 | |
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Yes |
General status |
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Antiinfective | |
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Pyrethroid insecticide; Pyrethroid acaricide; Pyrethroid ester insecticide; Pyrethroid ester acaricide | |
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Synthetic | |
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Contact and stomach action. Sodium channel modulator. | |
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[Sodium channel, Modulator] | |
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69409-94-5 | |
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805-993-1 | |
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432 | |
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109302 | |
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50516 | |
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No data found | |
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Nervous system: Anesthetics; Psycholeptics | |
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QP53AC10 | |
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No | |
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- | |
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502.91 | |
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(RS)-a-cyano-3-phenoxybenzyl N-(2-chloro-a,a,a-trifluoro-p-tolyl)-DL-valinate | |
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(RS)-α-cyano-3-phenoxybenzyl N-(2-chloro-α,α,α-trifluoro-p-tolyl)-DL-valinate | |
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cyano(3-phenoxyphenyl)methyl N-[2-chloro-4-(trifluoromethyl)phenyl]-DL-valinate | |
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Potential groundwater pollutant; PAN Bad Chemical Actor | |
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Viscous, yellow oil | |
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Formulations |
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0.002 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 3 = Unverified data of known source |
Low | ||||||||
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25 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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7.08 X 1003 | Calculated | - | |||||||
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3.85 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 3 = Unverified data of known source |
High | ||||||||
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Soluble | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Regulatory data - observed in metabolism and farm animal feeding studies | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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0.013 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 3 = Unverified data of known source |
Low volatility | ||||||||
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Degradation |
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7 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 3 = Unverified data of known source |
Non-persistent | |||||||
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General literature gives DT₅₀ 6-8 days | ||||||||||
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1 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 3 = Unverified data of known source |
Moderately fast | |||||||
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Stable | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 3 = Unverified data of known source |
Stable | |||||||
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Stable under normal environmental temperatures and pH | ||||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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1000000 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 3 = Unverified data of known source |
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Fate indices |
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Known soil and groundwater metabolites |
None
Other known metabolites |
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3-phenoxy benzoic acid | - | Water (photolysis) | - | ||||
anilino acid | - | Water (photolysis) | - |
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Terrestrial ecotoxicology |
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261 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) Rat3 = Unverified data of known source |
Moderate | ||||||||
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> 2510 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) Colinus virginianus3 = Unverified data of known source |
Low | ||||||||
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Aquatic ecotoxicology |
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0.0009 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) Lepomis macrochirus3 = Unverified data of known source |
High | ||||||||
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0.000033 | P3 P = Other non-EU, UK or US Governments and Regulators Pimephales promelas 30 day3 = Unverified data of known source |
High | ||||||||
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0.074 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) Daphnia magna3 = Unverified data of known source |
High | ||||||||
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0.0029 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) Americamysis bahia3 = Unverified data of known source |
High | ||||||||
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General |
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High (class III) | - | - | ||||||||
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261 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) Rat3 = Unverified data of known source |
Moderate | ||||||||
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20000 | G3 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 3 = Unverified data of known source |
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Mainly metabolised and excreated in urine but a proportion is excreted unchanged in faeces | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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Liver and kidney toxicant Endocrine issues - Binding to human sex hormone, inhibition of progesterone production |
Handling issues |
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Not explosive | |||
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II (Moderately hazardous) | |||
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fluvalinate | ||
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fluvalinate | ||
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Fluvalinate | ||
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fluvalinat | ||
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fluvalinato | ||
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fluvalinate | ||
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fluvalinate | ||
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fluwalinat | ||
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fluvalinat | ||
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fluvalinaat | ||
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Record last updated: | 26/08/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |