Amprolium hydrochloride
Last updated: 30/08/2023
(Not known by any other names)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
 
A veterinary drug mainly used to treat coccidiosis in poultry and other birds
Current
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Poultry, Dogs, Cats, Elephants, Pigeons
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C₁₄H₁₉N₄Cl
CCCC1=NC=C(C(=N1)N)C[N+]2=CC=CC=C2C.Cl.[Cl-]
No data
PJBQYZZKGNOKNJ-UHFFFAOYSA-M
InChI=1S/C14H19N4.2ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
amprolium hydrochloride
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Coccidiostat, Antiprotozoal agent, Antiparasitic
Thiamine analogue
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Synthetic
A thiamine analogue, blocks the thiamine transporter of Eimeria species
[Thiamine, antagonist]
137-88-2
205-307-5
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1349737338
QP51AX09
Antiparasitic products, insecticides & repellents: Antiprotozoals
No
Allowed substance (Table 1: Poultry)
315.24
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5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propyl-pyrimidin-4-amine chloride
1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-picolinium chloride
Not approved as a feed additive in EU
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White to off-white coloured powder
Harkers Pigeon Coccidiosis Treatment Concentrate
Harkers Ltd
UK National authorisation
Authorised veterinary medicine for general sale (AVM - GSL)
Usually supplied as a concentrate to add to drinking water
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>8
R4 R = Peer reviewed scientific publications 4 = Verified data
Slightly persistent
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Soil adsorption and mobility
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Terrestrial ecotoxicology
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HUMAN HEALTH AND PROTECTION
High (class III)
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Rapidly absorbed from the gastrointestinal tract and very rapidly excreted via the urine and faeces
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
?Possibly, status not identified
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
May cause stomach distress, nausea or vomiting
No information available
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Not listed (Not listed)
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amprolium hydrochloride
chlorhydrate d' amprolium
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hidrocloruro de amprolio
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Record last updated:
30/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242