L-glutamic acid ** 2-aminopentanedioic acid ** L-glutamate ** Translations

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GENERAL INFORMATION

Description: A naturally occurring amino acid that demonstrates fungicidal and plant growth regulation properties

Appearance and life cycle: -

Introduction: 1866, discovered and indentified;

Taxonomic classification: -

EC Directive 1107/2009 (repealing 91/414):

Status	Excluded from Annex 1
Dossier rapporteur/co-rapporteur	Not applicable
Date inclusion expires	-

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Known to used in the following countries: -

General status:

Biopesticide type	Plant growth regulator, Fungicide
Substance group	Plant & animal dervived (isomer mix)
Substance origin	Natural
Mode of action	Involved in many physiological functions
Substance source	A major amnio acid present in plant and animal proteins that is involved in many physiological functions
Substance production	Synthesised for commercial applications
Uses	Crop protection, Quality enhancement
Target pests	Powdery mildew and other fungal infections
Target host	Wide variety including fruit, vegetable, nuts, lawns/grass, ornamentals
Farming system suitability	IPM and organic systems where appropriate national approvals for use exist.
CAS RN	56-86-0
EC number	200-293-7
CIPAC number	-
US EPA chemical code	374350
Chiral molecule	No
Chemical formula	C5H9NO4
SMILES	[C@H](CCC(=O)O)(C(=O)O)N
International Chemical Identifier (InChI)	InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
Structure diagram/image available?	Yes
Molecular mass (g mol-1)	147.13
IUPAC Name	2-aminoglutaric acid
CAS Name	L-glutamic acid
Other status information	Food additive
Herbicide Resistance Classification (HRAC)	Not applicable
Insecticide Resistance Classification (IRAC)	Not applicable
Fungicide Resistance Classification (FRAC)	Not applicable
Physical state	White powdery solid
Related substances & organisms	gamma-aminobutyric acid

Formulations:

Property	Product	Manufacturer
Example products	Auxigro WP	Auxein Corporation
Formulation and application details	Usually supplied as a wettable powder and applied as a spray, soil drenchor via a suitable irrigation system.

ENVIRONMENTAL FATE

Property		Value	Source/Quality Score/Other Information	Interpretation
Solubility - In water at 20oC (mg l-1)		8640	V3	High
Solubility - In organic solvents at 20oC (mg l-1)		-	-	-
Melting Point (oC)		Decomposes on melting	V3	-
Boiling Point (oC)		-	-	-
Degradation point (oC)		199	V3	-
Flashpoint (oC)		-	-	-
Octanol-water partition coefficient at pH 7, 20oC	P	-	-	-
	Log P	-	-	-
Bulk density (g ml-1)/Specific gravity		1.4601	V3	-
Dissociation constant (pKa) at 25oC		-	2. - 3	-
		Note: V3
Vapour pressure at 25oC (mPa)		-	-	-
Henry's law constant at 25oC (Pa m3 mol-1)		-	-	-
Henry's law constant at 20oC (dimensionless)		-	-	-
Maximum UV-vis absorption L mol-1 cm-1		-	-	-
Surface tension (mN m-1)		-	-	-

Degradation:

Property		Value	Source/Quality Score/Other Information	Interpretation
Soil degradation (days) (aerobic)	DT50 (typical)	-	-	-
	DT50 (lab at 20oC)	-	-	-
	DT50 (field)	-	-	-
	DT90 (lab at 20oC)	-	-	-
	DT90 (field)	-	-	-
	Note:	-
Aqueous photolysis DT50 (days) at pH 7	Value	-	-	-
	Note	-
Aqueous hydrolysis DT50 (days) at 20oC and pH 7	Value	-	-	-
	Note	-
Water-Sediment DT50 (days)		-	-	-
Water phase only DT50 (days)		-	-	-

Soil adsorption and mobility:

Property		Value	Source/Quality Score/Other Information	Interpretation
Linear	Kd	-	-	-
	Koc	-
	Notes and range	-
Freundlich	Kf	-	-	-
	Kfoc	-
	1/n	-
	Notes and range	-
pH sensitivity		-

ECOTOXICOLOGY

Property		Value	Source/Quality Score/Other Information	Interpretation
Bio-concentration factor	BCF	-	-	-
	CT50 (days)	-		-
Bioaccumulation potential		-	-	-
Mammals - Acute oral LD50 (mg kg-1)		> 5000	L3 Rat	Low
Mammals - Short term dietary NOEL	(mg kg-1)	-	-	-
	(ppm diet)	-		-
Birds - Acute LD50 (mg kg-1)		-	-	-
Birds - Short term dietary (LC50/LD50)		-	-	-
Fish - Acute 96 hour LC50 (mg l-1)		> 100	V3 Unknown species, as product	Moderate
Fish - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1)		-	-	-
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1)		-	-	-
Aquatic plants - Acute 7 day EC50, biomass (mg l-1)		-	-	-
Algae - Acute 72 hour EC50, growth (mg l-1)		-	-	-
Algae - Chronic 96 hour NOEC, growth (mg l-1)		-	-	-
Honeybees - Acute 48 hour LD50 (µg bee-1)		-	-	-
Earthworms - Acute 14 day LC50 (mg kg-1)		-	-	-
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1)		-	-	-
Other soil macro-organisms - e.g. Collembola	LR50product ha EC50product ha NOECproduct ha % Effect	-	-	-
Other arthropod (1)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Other arthropod (2)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Soil micro-organisms		-	-	-
Mesocosm study data	NOEAEC mg l-1	-	-	-
	NOEAEC mg l-1	-	-	-

HUMAN HEALTH AND PROTECTION

General:

Property		Value	Source/Quality Score/Other Information	Interpretation
Mammals - Acute oral LD50 (mg kg-1)		> 5000	L3 Rat	Low
Mammals - Dermal LD50 (mg kg-1 body weight)		> 5000	L3 Rabbit	-
Mammals - Inhalation LC50 (mg l-1)		-	-	-
Other Mammal toxicity endpoints		-		-
ADI - Acceptable Daily Intake (mg kg-1bw day-1)		-	-	-
ARfD - Acute Reference Dose (mg kg-1bw day-1)		-	-	-
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1)		-	-	-
Dermal penetration studies (%)		-	-	-
Dangerous Substances Directive 76/464		-	-	-
Exposure Limits		-	-	-
Exposure Routes	Public	-
	Occupational	-

Health issues:

Carcinogen	Mutagen	Endocrine disrupter	Reproduction / development effects	Acetyl cholinesterase inhibitor	Neurotoxicant	Respiratory tract irritant	Skin irritant	Eye irritant
General human health issues		Regcognised by the US FDA as safefor human consumption

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:

Property		Value	Source/Quality Score/Other Information	Interpretation
General		No information available
CLP classification 2013		-
EC Risk Classification		Xi - Irritant: R36/37/38
EC Safety Classification		S24, S25, S36
WHO Classification		NL	-	Not listed
US EPA Classification (formulation)		-	-	-
UN Number		-
Waste disposal & packaging		-

TRANSLATIONS