gamma-aminobutyric acid ** GABA ** 4-aminobutyric acid ** piperidic acid ** piperidinic acid ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION

Description: A naturally occurring amino acid that demonstrates fungicidal and plant growth regulation properties

Appearance and life cycle: -

Introduction: -

Taxonomic classification: -

EC Directive 1107/2009 (repealing 91/414):

Status	Excluded from Annex 1
Dossier rapporteur/co-rapporteur	Not applicable
Date inclusion expires	-

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Known to used in the following countries: -

General status:

Biopesticide type	Plant growth regulator, Fungicide
Substance group	Plant & animal dervived
Substance origin	Natural
Mode of action	Via physiological processes
Substance source	A naturally occurring aminoacid found in bacteria, plants and animals
Substance production	Synthesised for commercial applications
Uses	Crop protection
Target pests	Powdery mildew and other fungal infections
Target host	Wide variety including fruit, vegetable, nuts, lawns/grass, ornamentals
Farming system suitability	IPM and organic systems where appropriate national approvals for use exist.
CAS RN	56-12-2
EC number	200-258-6
CIPAC number	-
US EPA chemical code	030802
Chemical formula	C4H9NO2
SMILES	C(C(O)=O)CCN
International Chemical Identifier (InChI)	InChI=1/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
Structure diagram/image available?	Yes
Molecular mass (g mol-1)	103.12
IUPAC Name	-
CAS Name	γ-aminobutyric acid
Other status information	-
Herbicide Resistance Classification (HRAC)	Not applicable
Insecticide Resistance Classification (IRAC)	Not applicable
Fungicide Resistance Classification (FRAC)	Not applicable
Physical state	Powdery solid
Related substances & organisms	L-glutamic acid

Formulations:

Property	Product	Manufacturer
Example products	Auxigro WP	Auxein Corporation
Formulation and application details	Usually supplied as a wettable powder and applied as a spray, soil drenchor via a suitable irrigation system.

ENVIRONMENTAL FATE

Property		Value	Source/Quality Score/Other Information	Interpretation
Solubility - In water at 20oC (mg l-1)		1300000	V3	High
Solubility - In organic solvents at 20oC (mg l-1)		-	-	-
Melting Point (oC)		195	V3	-
Boiling Point (oC)		-	-	-
Degradation point (oC)		-	-	-
Flashpoint (oC)		-	-	-
Octanol-water partition coefficient at pH 7, 20oC	P	6.76 X 10-04	Calculated	-
	Log P	-3.17	V3	Low
Bulk density (g ml-1)/Specific gravity		-	-	-
Dissociation constant (pKa) at 25oC		4.05	V3	-
		Note:
Vapour pressure at 25oC (mPa)		-	-	-
Henry's law constant at 25oC (Pa m3 mol-1)		-	-	-
Henry's law constant at 20oC (dimensionless)		-	-	-
Maximum UV-vis absorption L mol-1 cm-1		-	-	-
Surface tension (mN m-1)		-	-	-

Degradation:

Property		Value	Source/Quality Score/Other Information	Interpretation
Soil degradation (days) (aerobic)	DT50 (typical)	-	-	-
	DT50 (lab at 20oC)	-	-	-
	DT50 (field)	-	-	-
	DT90 (lab at 20oC)	-	-	-
	DT90 (field)	-	-	-
	Note:	-
Aqueous photolysis DT50 (days) at pH 7	Value	-	-	-
	Note	-
Aqueous hydrolysis DT50 (days) at 20oC and pH 7	Value	-	-	-
	Note	-
Water-Sediment DT50 (days)		-	-	-
Water phase only DT50 (days)		-	-	-

Soil adsorption and mobility:

Property		Value	Source/Quality Score/Other Information	Interpretation
Linear	Kd	-	-	-
	Koc	-
	Notes and range	-
Freundlich	Kf	-	-	-
	Kfoc	-
	1/n	-
	Notes and range	-
pH sensitivity		-

ECOTOXICOLOGY

Property		Value	Source/Quality Score/Other Information	Interpretation
Bio-concentration factor	BCF	-	-	-
	CT50 (days)	-		-
Bioaccumulation potential		-	Calculated	Low
Mammals - Acute oral LD50 (mg kg-1)		> 5000	L3 Rat	Low
Mammals - Short term dietary NOEL	(mg kg-1)	-	-	-
	(ppm diet)	-		-
Birds - Acute LD50 (mg kg-1)		-	-	-
Birds - Short term dietary (LC50/LD50)		-	-	-
Fish - Acute 96 hour LC50 (mg l-1)		> 100	V3 Unknown species, as product	Moderate
Fish - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1)		-	-	-
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1)		-	-	-
Aquatic plants - Acute 7 day EC50, biomass (mg l-1)		-	-	-
Algae - Acute 72 hour EC50, growth (mg l-1)		-	-	-
Algae - Chronic 96 hour NOEC, growth (mg l-1)		-	-	-
Honeybees - Acute 48 hour LD50 (µg bee-1)		-	-	-
Earthworms - Acute 14 day LC50 (mg kg-1)		-	-	-
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1)		-	-	-
Other soil macro-organisms - e.g. Collembola	LR50product ha EC50product ha NOECproduct ha % Effect	-	-	-
Other arthropod (1)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Other arthropod (2)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Soil micro-organisms		-	-	-
Mesocosm study data	NOEAEC mg l-1	-	-	-
	NOEAEC mg l-1	-	-	-

HUMAN HEALTH AND PROTECTION

General:

Property		Value	Source/Quality Score/Other Information	Interpretation
Mammals - Acute oral LD50 (mg kg-1)		> 5000	L3 Rat	Low
Mammals - Dermal LD50 (mg kg-1 body weight)		> 5000	L3 Rabbit	-
Mammals - Inhalation LC50 (mg l-1)		-	-	-
Other Mammal toxicity endpoints		Intraperitoneal LD50 = 4950 mg kg-1	V3 Mice	-
		Intravenous LD50 = 2748	V3 Mice	-
ADI - Acceptable Daily Intake (mg kg-1bw day-1)		-	-	-
ARfD - Acute Reference Dose (mg kg-1bw day-1)		-	-	-
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1)		-	-	-
Dermal penetration studies (%)		-	-	-
Dangerous Substances Directive 76/464		-	-	-
Exposure Limits		-	-	-
Exposure Routes	Public	-
	Occupational	-
Elimination route and rate		-	-	-

Health issues:

Carcinogen	Mutagen	Endocrine disrupter	Reproduction / development effects	Acetyl cholinesterase inhibitor	Neurotoxicant	Respiratory tract irritant	Skin irritant	Eye irritant
-	-	-	-	-	-
General human health issues		[Toxic by ingestion, skin contact and inhalation]

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:

Property		Value	Source/Quality Score/Other Information	Interpretation
General		[No information available]
EC Risk Classification		[Xn - Harmful: R20/21/22], [Xi - Irritant: 36/37/38]
EC Safety Classification		S26-S36
WHO Classification		NL	-	Not listed
US EPA Classification (formulation)		-	-	-
UN Number		-
Waste disposal & packaging		-

TRANSLATIONS