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acequinocyl
** kanemite ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

Acequinocyl is an acaricide that is currently being evaluated for EU use. It is not highly soluble in water but is highly soluble in most organic solvents. It is volatile. It is not expected to leach to groundwater. It is not mobile and tends not to be persistence in soil or aquatic systems. It has a low mammalian toxicity and there is some concern regarding its potential for bioaccumulation. Acequinocyl is moderately toxic to birds, fish, honeybees and earthworms and highly toxic to aquatic invertebrates.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for acequinocyl

Description: An unclassified acaricide effective against all mite development stages on, for example, ornamentals and top fruit

Example pests controlled: Mites including spider mites, spruce spider mite and red palm mite; Ticks

Example applications: Greenhouse crops; Ornamentals; Nursery crops; Fruits including strawberries, apples, pears, apricots, plums, grapes, citrus; Tree nuts; Pistachios

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1999, Japan and Korea

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Netherlands
Date inclusion expires 31/08/2024
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism None
Chemical formula C24H32O4
Canonical SMILES CCCCCCCCCCCCC1=C(C(=O)C2=CC=CC=C2C1=O)OC(=O)C
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) QDRXWCAVUNHOGA-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Acaricide
Substance group Unclassified
Minimum active substance purity 96%
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Mainly contact action but some via ingestion. Mitochondrial complex III electron transport inhibitor.
CAS RN 57960-19-7
EC number -
CIPAC number 760
US EPA chemical code 006329
PubChem CID 93315
Molecular mass (g mol-1) 384.51
PIN (Preferred Identification Name) 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate
IUPAC name 3-dodecyl-1,4-dihydro-1,4-dioxo-2-naphthyl acetate
CAS name 2-(acetyloxy)-3-dodecyl-1,4-naphthalenedione
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 20B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Plutella xylostella
Physical state Pale yellow to light brown powdery flakes
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically -
Example products using this active
  • Kanemite
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Foliar spray application.


ENVIRONMENTAL FATE

for acequinocyl

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 0.007 A5 Low
Solubility - In organic solvents at 20oC (mg l-1) 250000 A5 - Xylene -
250000 A5 - Dichloroethane -
29200 A5 - 1-Octanol -
6100 A5 - Methanol -
Melting point (oC) 59.6 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 200 L3 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 1.58 X 1006 Calculated -
Log P 6.2 A5 High
Bulk density (g ml-1)/Specific gravity 1.13 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 1.69 X 10-03 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 9.7 X 10-02 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -0.30 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 Acidic solution: 242nm = 16524, 248nm = 16989, 270nm = 13905, 335nm = 2836; [Neutral solution: 242nm = 16582, 248nm = 16873, 270nm = 13207, 271nm = 2851; [Basic solution: 232nm = 19055, 245nm = 13149, 275nm = 2172, 362nm = 8999 A5 -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 2.0 A5 Non-persistent
DT50 (lab at 20oC) 2.0 A5 Non-persistent
DT50 (field) 0.1 A5 Non-persistent
DT90 (lab at 20oC) 6.3 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 1.1-2.7 days, DT90 3.6-8.9 days; field studies DT50 range 2-3 hours; Other sources: pH sensitive. DT50 in alkaline soils < 2 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value 1.6 R3 -
Note Perilla leaves, n=1
Aqueous photolysis DT50 (days) at pH 7 Value 0.02 A5 Fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 2.2 A5 Non-persistent
Note DT50 pH sensitive: 74 days at pH 4, 67 minutes at pH 9
Water-sediment DT50 (days) 0.45 A5 Fast
Water phase only DT50 (days) 0.5 A5 Fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd 1027 A5 Non-mobile
Koc 66033
Notes and range EU dossier Kd range 678-1620 mL/g, Koc range 3390-123000 mL/g (later dossier gives range as 39900-123000 mL/g), Soils=4
Freundlich Kf - - Non-mobile
Kfoc 100666
1/n -
Notes and range -
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
2-dodecyl-3-hydroxy-1,4-naphthoquinone This metabolite may cause environmental pollution, click here for further information Soil   0.338   Major fraction, Relevant
2-(1',2'-dioxotetradecyl)benzoic acid (Ref: AKM-18) This metabolite may cause environmental pollution, click here for further information Soil   0.219   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
2-(carboxycarbonyl)benzoic acid
Note: Low risk to fish
CBAA Surface Water 0.11 -


ECOTOXICOLOGY

for acequinocyl

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 366 A5 Threshold for concern
CT50 (days) 0.7 -
Mammals - Acute oral LD50 (mg kg-1) > 4855 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) 9 L2 Rat High
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 1942 A5 Anas platyrhynchos Moderate
Birds - Short term dietary (LC50/LD50) > 847 mg kg bw-1 day-1 A5 Coturnix japonica -
Fish - Acute 96 hour LC50 (mg l-1) > 100 L3 Oncorhynchus mykiss Low
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0039 A5 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.00098 A5 Daphnia magna High
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.00093 A5 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) 0.479 A5 Chironomus riparius Moderate
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 100 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 100 A5 Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 1000 A5 Low
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect 0 Mortality
Dose: 1.05 kg ha-1
A5 Aphidius rhopalosiphi
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect 8.52 Mortality
Dose: 0.3 kg ha-1
A5 Typhlodromus pyri
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 5.25 kg ha-1
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for acequinocyl

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class Intermediate (class II) - -
Mammals - Acute oral LD50 (mg kg-1) > 4855 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 0.84 A5 Rat, 4 hr (aerosol, nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.023 A3 proposed Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.08 A3 proposed Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.014 A3 proposed Rat, SF=100 -
Dermal penetration studies (%) 16.7 A4 -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Exposure by any route is unlikely
Source: US EPA/A5
Occupational Small risk of dermal short-term exposure
Risk of chronic exposure is low
Source: US EPA/A5
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Blood toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes No information available
CLP classification 2013 Health: H370, H317; H373
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases T - Toxic: R39/23
Xn - Harmful: R43
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases -
WHO Classification NL - Not listed
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for acequinocyl

Language Name
English acequinocyl
French acequinocyl
German Acequinocyl
Danish acequinocyl
Italian acequinocil
Spanish acequinocil
Greek -
Slovenian acekvinocil
Polish acekwinocyl
Swedish -
Hungarian -
Dutch -

Record last updated: Thursday 23 August 2018
Contact: aeru@herts.ac.uk