Pyrithiobac-sodium (Ref: DPX PE 350)
Last updated: 19/01/2023
(Also known as: KIH 2031)
Pyrithiobac-sodium is a post-emergence herbicide. It has a high aqueous solubility, is semi-volatile and, based on its chemical properties, it is very mobile and has high potential to leach to groundwater. It is generally moderately persistent in soil systems but tends to be non-persistent in aquatic systems. It has a low mammalian toxicity but may bioaccumulate. It shows a low to moderate level of toxicity to most biodiversity.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
Post-emergence control of broad-leaved weeds in cotton and other crops
Cocklebur; Goosefoot; Nightshade; Knotweed; Pigweed; Rocket; Shepherd's purse; Sunflower; velvetleaf; Morning glory; Purslane
Cotton
-
Current
1995, USA
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
None
C₁₃H₁₀ClN₂NaO₄S
COC1=CC(=NC(=N1)SC2=C(C(=CC=C2)Cl)C(=O)[O-])OC.[Na+]
-
CNILNQMBAHKMFS-UHFFFAOYSA-M
InChI=1S/C13H11ClN2O4S.Na/c1-19-9-6-10(20-2)16-13(15-9)21-8-5-3-4-7(14)11(8)12(17)18;/h3-6H,1-2H3,(H,17,18);/q;+1/p-1
Yes
Herbicide
Pyrimidinyloxybenzoic acid herbicide
-
-
Synthetic
Causes tissue death. Inhibits plant amino acid synthesis - acetohydroxyacid synthase AHAS.
123343-16-8
602-931-3
-
078905
23682187
No data found
348.74
sodium 2-chloro-6-[(4,6-dimethoxypyrimidin-2-yl)sulfanyl]benzoate
sodium 2-chloro-6-(4,6-dimethoxypyrimidin-2-ylthio)benzoate
sodium 2-chloro-6-[(4,6-dimethoxy-2-pyrimidinyl)thio]benzoate
-
-
B
2
Not applicable
Not applicable
Amaranthus palmeri
Off-white powder
DuPont Kumiai Chemical Industry Co. Ltd.
Usually supplied as a soluble powder
728000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
812
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
270000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Methanol
-
10
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
n-Hexane
-
205
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Ethyl acetate
-
234
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
234
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
1.45 X 10-01
Calculated
-
-0.84
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
-
-
-
-
-
-
1.61
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
2.34
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Strong acid
4.80 X 10-06
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
-
-
-
-
-
-
-
-
-
-
60
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately persistent
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
General literature data states DT₅₀ 60 days in silty soil. DT₅₀ 10 days for uplands and flooded soil. Main degradation route is microbial.
-
-
-
-
-
-
-
-
13
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately fast
pH sensitive: DT₅₀ 11 days at pH 5, 15 days at pH 9, all at 25 °C
Stable
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Stable
-
-
-
-
-
-
-
Soil adsorption and mobility
0.5
-
-
General literature data gives Kd values ranging from 0.32 (sandy loam) to 0.75 (silty loam). Peered review study - Kd 0.22 to 0.59 L/kg
-
-
-
-
-
-
-
-
-
-
Cannot be calculated
-
-
-
-
-
-
-
-
-
Low risk
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
Based on LogP < 3
Low risk
-
-
None
Terrestrial ecotoxicology
3200
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
-
-
-
-
-
-
-
-
> 1500
Anas platyrhynchos
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 25
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 930
Lepomis macrochirus
Low
-
-
-
> 1100
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
Low
260
P3 P = Other governments and regulators 3 = Unverified data of known source
Daphnia magna
Low
> 140.0
Americamysis bahia
Low
-
-
-
-
-
-
-
-
-
0.0009
Lemna gibba
High
95.0
Selenastrum capricornutum
Low
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
3200
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rabbit
-
6.9
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
?Possibly, status not identified
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
Moderately toxic Possible liver toxicant USEPA - possible human carcinogen
No information available
-
III (Slightly hazardous)
-
-
pyrithiobac-sodium
-
-
-
-
piritiobac sodico
-
pirytiobak sodowy
-
-
-
Record last updated:
19/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242