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glyphosate trimesium
** trimethylsulfonium glyphosate ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

Glyphosate trimesium is a non-selective common and effective herbicide. It is highly soluble in water, non-volatile and does not normally leach to groundwater. It is not persistent in soils but may be in aquatic systems under certain conditions. It is moderately toxic to humans and a skin and eye irritant. It is moderately toxic to birds, most aquatic organisms, earthworms and honeybees.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for glyphosate trimesium

Description: A herbicide used in a wide range of cropping, utility and industrial situations for broad-spectrum control of weeds and grases

Example pests controlled: Annual and perennial weeds, Broad-leaved weeds, Grasses

Example applications: Cereals; Soybeans; Glyphosate tolerant crops; Horticulture; Forestry; Domestic gardens, lawns

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1971, first reported; 1989, introduced in Spain

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Germany/Slovakia
Date inclusion expires 15/12/2022
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C6H16NO5PS
Canonical SMILES C[S+](C)C.C(C(=O)O)NCP(=O)(O)[O-]
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) RUCAXVJJQQJZGU-UHFFFAOYSA-M
International Chemical Identifier (InChI) InChI=1S/C3H8NO5P.C3H9S/c5-3(6)1-4-2-10(7,8)9;1-4(2)3/h4H,1-2H2,(H,5,6)(H2,7,8,9);1-3H3/q;+1/p-1
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Glycine derivative
Minimum active substance purity 950 g/kg as acid
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Broad-spectrum, systemic, translocated and non-residual. Inhibition of EPSP synthase.
CAS RN 81591-81-3
EC number 213-997-4
CIPAC number 284
US EPA chemical code 128501
PubChem CID 105048
Molecular mass (g mol-1) 245.23
PIN (Preferred Identification Name) trimethylsulfonium N-[(hydroxyphosphinato)methyl]glycine
IUPAC name trimethylsulfonium N-[(hydroxyphosphinato)methyl]glycine
CAS name 2-(phosphonomethylamino)acetate; trimethylsulfonium
Other status information Risk of herbicide resistance developing - anti-resistance management required; PAN listed Highly Hazardous Chemical
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) G
Herbicide Resistance Classification (WSSA) 9
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Eleusine indica
Euphorbia heterophylla
Physical state White solid
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Monsanto
  • Syngenta
Example products using this active
  • Coloso
  • Ouragan
  • Zapp
UK LERAP status None (may vary with mixtures)
Formulation and application details Often supplied as a soluble concentrate that is mixed with water and applied as a spray.


ENVIRONMENTAL FATE

for glyphosate trimesium

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 1050000 A5 High
Solubility - In organic solvents at 20oC (mg l-1) 50 A5 - Acetone -
50 A5 - Xylene -
50 A5 - Heptane -
174000 A5 - Methanol -
Melting point (oC) Decomposes before melting A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) - - -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 1.26 X 10-03 Calculated -
Log P -2.9 A5 Low
Bulk density (g ml-1)/Specific gravity 1.42 A5 -
Dissociation constant (pKa) at 25oC - A5 -
Note: Fully dissociated in water
Vapour pressure at 20oC (mPa) 0.00000001 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.0 X 10-09 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -0.65 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 17 Q3 Non-persistent
DT50 (lab at 20oC) 29 A5 Non-persistent
DT50 (field) 22 A5 Non-persistent
DT90 (lab at 20oC) 144 A5 -
DT90 (field) 149 A5 -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 3-62days, DT90 range 81-207 days, field studies DT50 range 1.5-34 days USA and Germany, DT90 range 76-326 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 81 A5 Stable
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable pH 5 to pH 9 up to 50 degC
Water-sediment DT50 (days) 183 A5 Slow
Water phase only DT50 (days) 16 A5 Slow

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 0.93 A5 Non-mobile
Kfoc 27621
1/n 0.97
Notes and range EU dossier Kfoc 530-180000 mL/g, 1/n range 0.84-1.1
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
aminomethylphosphonic acid This metabolite may cause environmental pollution, click here for further information Soil   0.154   Major fraction, Relevant


ECOTOXICOLOGY

for glyphosate trimesium

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk A5 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) 748 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 950 A4 Unknown species Moderate
Birds - Short term dietary (LC50/LD50) > 5000 mg kg feed-1 A4 Unknown species -
Fish - Acute 96 hour LC50 (mg l-1) 1800 A4 Oncorhynchus mykiss Low
Fish - Chronic 21 day NOEC (mg l-1) 50 A5 Oncorhynchus mykiss Low
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 12 A4 Unknown species Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 1.1 A4 Unknown species Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 16.0 F3 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 12 A4 Unknown species Low
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) 0.72 A4 Unknown species Moderate
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 400 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 400 A5 Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 1000 A5 Eisenia foetida Low
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 28.8 A5 Eisenia foetida Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 8400 48 hour
A5 Aphidius rhopalosiphi
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 5089 A5 Typhlodromus pyri -
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 18 kg ha-1
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for glyphosate trimesium

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 748 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 5.0 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.3 A5 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.5 A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.2 A5 -
Dermal penetration studies (%) 1.0 A5 -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues IARC group 2A carcinogen
Possible bladder and liver toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes IMDG Transport Code is usually 9
CLP classification 2013 Health: H318
Environment: H411
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R22
N - Dangerous for the environment: R51, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S36/37, S46, S61
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number Variable with product, usually 3077 or 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for glyphosate trimesium

Language Name
English glyphosate trimesium
French -
German -
Danish -
Italian -
Spanish -
Greek -
Slovenian glifosat-trimesium
Polish glifosat-trimesium
Swedish -
Hungarian -
Dutch -

Record last updated: Wednesday 31 October 2018
Contact: aeru@herts.ac.uk