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GET ADDITIONAL DATA HERE!

fluroxypyr-meptyl
** fluroxypyr-MHE ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for fluroxypyr-meptyl

Description: A post-emergence herbicide used to control economically important broad-leaved weeds

Example pests controlled: Annual and perennial broad-leaved weeds including kochia, lespedeza and dogfennel; Woody brush

Example applications: Rangeland; Permanent pasture; Non-crop areas; Cereals including wheat, corn

Efficacy & activity: -

Availability status: Current

Introduction & key dates: -

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Sweden/Slovenia
Date inclusion expires 31/12/2021
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism Fluroxypyr is not itself isomeric but the meptyl ester has a pair of enantiomers.
Chemical formula C15H21Cl2FN2O3
Canonical SMILES CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) OLZQTUCTGLHFTQ-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Pyridine compound
Minimum active substance purity 950 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Selective, foliar uptake causing auxin-type response
CAS RN 81406-37-3
EC number 279-752-9
CIPAC number -
US EPA chemical code 128968
PubChem CID 54745
Molecular mass (g mol-1) 367.24
PIN (Preferred Identification Name) rac-(2R)-octan-2-yl [(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxy]acetate
IUPAC name (RS)-1-methylheptyl 4-amino-3,5-dichloro-6-fluoro-2-pyridyloxyacetate
CAS name 1-methylheptyl ((4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy)acetate
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) O
Herbicide Resistance Classification (WSSA) 4
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Cabbage family; other dicotyldons such as bugloss, comon poppy, corn marigold
Physical state White crystalline solid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Barclay Chemicals
  • Dow AgroSciences
  • Agrotech
  • AgriGuard
Example products using this active
  • Agrostar
  • Bofix FFC
  • Awac
  • Cabadex
  • Cascade
UK LERAP status None (may vary with mixtures)
Formulation and application details Often supplied as an emulsifiable concentrate that is mixed with water and applied as a spray.


ENVIRONMENTAL FATE

for fluroxypyr-meptyl

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 0.136 A5 Low
Solubility - In organic solvents at 20oC (mg l-1) 62300 A5 - n-Heptane -
3770000 A5 - Methanol -
3300000 A5 - Acetone -
2500000 A5 - Ethyl acetate -
Melting point (oC) 57.5 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 312 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 1.10 X 1005 Calculated -
Log P 5.04 A5 High
Bulk density (g ml-1)/Specific gravity 1.322 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 0.01 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.7 X 10-02 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.00 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 290nm=10.01, no maxama 290-900nm A5 -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 1.0 A5 Non-persistent
DT50 (lab at 20oC) 1.0 A5 Non-persistent
DT50 (field) 3 A5 Non-persistent
DT90 (lab at 20oC) 2.8 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 0.5-1.8 days; DT90 range 1.0-6.0 days; Other studies: DT50 3-55 days (lab), 34-70 (field)
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value 2.69 R3 -
Note Rice, whole plant, n=1
Aqueous photolysis DT50 (days) at pH 7 Value 63 A5 Stable
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note At pH 5 stable; At pH 9 DT50 = 3.2 days
Water-sediment DT50 (days) 34.7 A5 Moderately fast
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd 188.75 A5 Non-mobile
Koc 19550
Notes and range EU dossier (2011) Kd range 95-260 mL/g, Koc range 6200-43000 ml/g, soils =4
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
4-amino-3,5-dichloro-6-fluoro-2-pyridinol This metabolite may cause environmental pollution, click here for further information Soil   0.115   -
4-amino-3,5-dichloro-6-fluoro-2-pirydynil-2-methoxypyridine This metabolite may cause environmental pollution, click here for further information Soil   0.178   -
fluroxypyr (Ref: DOW 43304-H)   -   -


ECOTOXICOLOGY

for fluroxypyr-meptyl

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) - - -
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 2000 A5 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) > 5000 mg kg feed-1 A5 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) > 0.225 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.2 A5 Oncorhynchus mykiss Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 0.183 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.06 A5 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) 0.13 A5 Chironomus riparius Moderate
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) > 2.31 A5 Lemna gibba Moderate
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) > 0.5 A5 Scenedemus subspicatus Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 100 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 100 A5 Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 1000 A5 Low
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 1301 A5 Aphidius rhopalosiphi -
% Effect 100 Mortality
Dose: 578 g ha-1
A5 Aphidius rhopalosiphi
-
Other arthropod (2) LR50 g ha-1 2200 >
A5 Typhlodromus pyri
-
% Effect 33.3 Mortality
Dose: 578 g ha-1
A5 Typhlodromus pyri
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 2 kg ha-1
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for fluroxypyr-meptyl

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 1.0 A5 Rat, 4 hr -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.8 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) None allocated A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.8 A5 Rat, SF=100 -
Dermal penetration studies (%) 4-22 A5 concentration dependent -
Dangerous Substances Directive 76/464 List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Possible kidney toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Prevent generation of mists
Not explosive or oxidising
CLP classification 2013 Environment: H412
EC Risk Classification Click here to view information omn the EU risk phrases N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S60, S61
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number Usually 3077
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for fluroxypyr-meptyl

Language Name
English fluroxypyr-meptyl
French fluoroxypyr-meptyl
German -
Danish -
Italian -
Spanish fluroxipir meptil
Greek -
Slovenian -
Polish fluroksypyr meptylu
Swedish fluroxipyr-1-metylheptylester
Hungarian -
Dutch -

Record last updated: Thursday 23 August 2018
Contact: aeru@herts.ac.uk