Kasugamycin hydrochloride hydrate
Last updated: 24/11/2022
(Also known as: kasugamycin HCl; kasumin)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
An aminoglycoside antibiotic used against bacteria and some fungi.
Bacterial rot (Erwinia atroseptica ); Leaf mold (Cladosporium fulvum ); Bacteria spot (Xanthomonas campestris, pv vesicatoria ), Rice blast; Scab
Tomatoes; Peppers; Rice; Potatoes; Sugar beet; Celery, Apples
-
Current
1965
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Netherlands
Expired
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
A chiral molecule
C₁₄H₂₈ClN₃O₁₀
CC1C(CC(C(O1)OC2C(C(C(C(C2O)O)O)O)O)N)N=C(C(=O)O)N.Cl
C[C@@H]1[C@H](C[C@@H]([C@H](O1)OC2[C@@H]([C@H](C([C@@H]([C@@H]2O)O)O)O)O)N)N=C(C(=O)O)N.Cl
ZDRBJJNXJOSCLR-NZXABURVSA-N
InChI=1S/C14H25N3O9.ClH/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22;/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24);1H/t3-,4+,5+,6-,7+,8+,9-,10+,11+,14-;/m1./s1
Yes
Fungicide, Antibiotic, Other substance
Bactericide, Wood preservative
Micro-organism derived substance
-
-
Natural
Contact action resulting in the inhibition of protein biosynthesis reducing bacterial growth and reproduction (bacteriostatic), rather than killing the bacteria directly.
19408-46-9
6980-18-3
-
703
230001
-
433.8
-
D-chiro-Inositol, 3-O-(2-amino-4-((carboxyiminomethyl)amino)-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl)-monohydrochloride
2-[[5-amino-2-methyl-6-(2,3,4,5,6-pentahydroxycyclohexyloxy)tetrahydropyran-3-yl]amino]-2-iminoacteic acid hydrochloride hydrate
-
-
Not applicable
Not applicable
Not applicable
24
Some strains of P. oryzae
-
Arysta Lifescience USA Hokko Chemical Industry Co. Ltd
Available in a variety of formulations including wettable powders, granules and soluble concentrates and applied as a foliar spray
228000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
7440
Methanol
-
0.0001
Hexane
-
0.0001
Methylene chloride
-
203
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
9.12 X 1001
Calculated
-
1.96
Low
-
-
-
-
-
-
0.43
-
3.23
-
Weak Acid, Pka(2) = 7.73, pKa(3) = 11.0
0.013
Low volatility
2.9 X 10-08
Non-volatile
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Literature states that substance rapidly breaks down to form ammonia, water and carbon dioxide
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-
-
-
-
-
-
-
-
-
-
-
14
Non-persistent
Data for pH 9
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-
-
-
-
-
Soil adsorption and mobility
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-
-
Cannot be calculated
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-
-
-
-
-
-
-
-
-
-
-
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-
Major fraction
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-
-
-
-
-
-
Secondary metabolite
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-
Secondary metabolite
Known groundwater metabolites
None
kasuganobiosamine
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Plant
-
-
ammonia Note: Secondary metabolite
-
Plant
-
-
oxalic acid Note: Secondary metabolite
-
Plant
-
-
Terrestrial ecotoxicology
> 5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
-
-
-
-
-
-
-
-
> 4000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Coturnix japonica
Low
-
-
-
-
-
-
> 1000
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
Eisenia foetida
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 40
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderate
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-
-
-
-
-
-
-
-
-
-
-
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-
-
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-
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-
-
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-
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-
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-
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-
-
-
-
-
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-
-
-
-
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-
> 40
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Cyprinus carpio
Moderate
-
-
-
> 40
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia pulex
Moderate
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-
-
-
-
-
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-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
2000
Rabbit
-
4.89
Rat
-
Subcutaneous LD₅₀ > 17000 mg kg⁻¹
Rat
-
Intraperitoneal LD₅₀ = 12000 mg kg⁻¹
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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EU MRL pesticide database 
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-
-
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
?Possibly, status not identified
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
No further information available
No information available
-
U (Unlikely to present an acute hazard)
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-
kasugamycin hydrochloride hydrate
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-
-
-
kasugamicina HCl
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-
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-
Record last updated:
24/11/2022
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242