Chlorfenapyr (Ref: MK 242) |
![]() Last updated: 22/12/2020 |
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(Also known as: AC 303630; CL 303630) |
SUMMARY |
Chlorfenapyr is a broad spectrum insecticide that does not have EU approval for use. It has a low aqueous solubility, low volatility and, based on its chemical properties, would not normally be expected to leach to groundwater. It is not usually persistent in soil or water systems. It has a moderate mammalian oral toxicity but no other data on human health impact has been identified. There are also gaps in ecotoxicilogical data but it is know to be highly toxic to birds, fish and aquatic invertebrates. |
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Used to control many insects and mites including those resistant to carbamate, organophosphate and pyrethroid compounds | |
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Spider mites; Caterpillars; Thrips; Fungus gnats | |
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Greenhouse ornamentals | |
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Current | |
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2001, USA |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Spain | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Australia |
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Chemical structure |
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Isomeric | |
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C₁₅H₁₁BrClF₃N₂O | |
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CCOCN1C(=C(C(=C1C(F)(F)F)Br)C#N)C2=CC=C(C=C2)Cl | |
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No data | |
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CWFOCCVIPCEQCK-UHFFFAOYSA-N | |
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InChI=1S/C15H11BrClF3N2O/c1-2-23-8-22-13(9-3-5-10(17)6-4-9)11(7-21)12(16)14(22)15(18,19)20/h3-6H,2,8H2,1H3 | |
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Yes |
General status |
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Insecticide, Acaricide, Miticide | |
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Pyrrole | |
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- | |
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Synthetic | |
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Limited systemic activity, mainly stomach but some contact action. Uncoupler of oxidative phosphorylation. | |
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122453-73-0 | |
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- | |
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570 | |
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129093 | |
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91778 | |
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407.62 | |
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4-bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile | |
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4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethyl-1H-pyrrole-3-carbonitrile | |
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4-bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile | |
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Chemical subject to PIC regulations | |
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- | |
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Not applicable | |
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Not applicable | |
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13 | |
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Not applicable | |
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Earias vittella, Tetranychus urticae | |
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White powdery solid |
Formulations |
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Usually supplied as suspension concentrate |
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0.112 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) at 25 °C3 = Unverified data of known source |
Low | ||||||||
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8900 | CA3 CA = Medical and toxicological databases and information systems e.g. TOXNET (click here ) Hexane3 = Unverified data of known source |
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70900 | CA3 CA = Medical and toxicological databases and information systems e.g. TOXNET (click here ) Methanol3 = Unverified data of known source |
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754000 | CA3 CA = Medical and toxicological databases and information systems e.g. TOXNET (click here ) Toluene3 = Unverified data of known source |
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1410000 | CA3 CA = Medical and toxicological databases and information systems e.g. TOXNET (click here ) Dichloromethane3 = Unverified data of known source |
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101 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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6.76 X 1004 | Calculated | - | |||||||
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4.83 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
High | ||||||||
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1.53 | Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source |
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Not applicable | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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No dissociation | |||||||||||
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9.81 X 10-03 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) at 25 °C3 = Unverified data of known source |
Low volatility | ||||||||
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5.81 X 10-04 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) at 25 °C3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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1.4 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Non-persistent | |||||||
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2.87 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 2.85-2.89 days, 2 crops, various matrices, n=2 | ||||||||||
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3.7 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 1.4-7.0 days, 8 field and undercover grown crops, various matrices, n=11 | ||||||||||
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6.2 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderately fast | |||||||
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Stable | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Stable | |||||||
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Stable pH 4 to pH 9 | ||||||||||
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Soil adsorption and mobility |
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- | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Non-mobile | |||||||
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12000 | ||||||||||
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Fate indices |
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-0.01 | Calculated | Low leachability | ||||||||||||||||||||||||||
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5.35 X 10-03 | Calculated | - | |||||||||||||||||||||||||
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Estimated concentrations of chemicals with Koc values greater than 9995 ml g⁻¹ are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW | ||||||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Non-mobile | Calculated | - |
Key metabolites |
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Soil | - | - |
Other known metabolites |
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Ref: CL 303268 | - | - | - | - | |||||
Ref: CL 303268 | - | - | - | - |
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- | F1 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 1 = Estimated data with little or no verification |
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Not available | - | |||||||||
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441 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
Moderate | ||||||||
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10 | L3 L = Pesticide manuals and hard copy reference books / other sources Colinus virginianus3 = Unverified data of known source |
High | ||||||||
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0.007 | L3 L = Pesticide manuals and hard copy reference books / other sources Oncorhynchus mykiss3 = Unverified data of known source |
High | ||||||||
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> 0.00871 | P3 P = Other governments and regulators Cyprinodon variegatus 33 day3 = Unverified data of known source |
High | ||||||||
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0.0061 | L3 L = Pesticide manuals and hard copy reference books / other sources Daphnia magna3 = Unverified data of known source |
High | ||||||||
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0.00357 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna3 = Unverified data of known source |
High | ||||||||
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0.12 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Apis mellifera3 = Unverified data of known source |
High | ||||||||
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General |
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High (class III) | - | - | ||||||||
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441 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
Moderate | ||||||||
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2000 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rabbit4 = Verified data |
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1.9 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
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0.015 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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0.015 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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List II | - | - | ||||||||
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Occupational exposure may occur through dermal contact | ||||||||||
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Health issues |
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Possile testicular and uterine toxicant USEPA - some evidence to suggest possible human carcinogen |
Handling issues |
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No information available | |||
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Health: H302, H331 Environment: H400, H410 |
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T - Toxic: R23 Xn - Harmful: R22 N - Dangerous for the environment: R50, R53 |
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S1/2, S13, S36/37, S45, S60, S61 | |||
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II (Moderately hazardous) | |||
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chlorfenapyr | ||
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chlorfénapyr | ||
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Chlorfenapyr | ||
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chlorfenapyr | ||
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clorfenapir | ||
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clorfenapir | ||
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chlorfenapyr | ||
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chlorofenapir | ||
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chloorfenapyr |
Record last updated: | 22/12/2020 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |