Disodium octaborate tetrahydrate

Disodium octaborate tetrahydrate	Last updated: 18/01/2021
(Also known as: boron sodium oxide; sodium octaborate; DOT; aquabor)

GENERAL INFORMATION

Description

A naturally occuring alkaline borate that may be used as an insecticide and fungicide

Example pests controlled

Termites; Powder post beetles; Carpenter ants; Fungi and algae; Molluscs; Mildew

Example applications

Non-food situations

Efficacy & activity

Availability status

Current

Introduction & key dates

1990, first use as wood preservative, USA; 1983, registered USA for cockroach control

UK regulatory status

UK COPR regulatory status

Not approved

Date COPR inclusion expires

Not applicable

UK LERAP status

No UK approval for use or outside scope

EC Regulation 1107/2009 (repealing 91/414)

EC Regulation 1107/2009 status

Not approved

Dossier rapporteur/co-rapporteur

Not applicable

Date EC 1107/2009 inclusion expires

Not applicable

EU Candidate for substitution (CfS)

Not applicable

Listed in EU database

Yes

Approved for use (✓) under EC 1107/2009 in the following EU Member States

ATAustria	BEBelgium	BGBulgaria	CYCyprus	CZCzech Republic	DEGermany	DKDenmark	EEEstonia	ELGreece

ESSpain	FIFinland	FRFrance	HRCroatia	HUHungary	IEIreland	ITItaly	LTLithuania	LULuxembourg

LVLatvia	MTMalta	NLNetherlands	PLPoland	PTPortugal	RORomania	SESweden	SISlovenia	SKSlovakia

Also used in

Chemical structure

Isomerism

None

Chemical formula

B₈H₈Na₂O₁₇

Canonical SMILES

B(=O)OB1OB2OB(OB(OB(O2)OB(O1)OB=O)[O-])[O-].O.O.O.O.[Na+].[Na+]

Isomeric SMILES

No data

International Chemical Identifier key (InChIKey)

RDMZIKMKSGCBKK-UHFFFAOYSA-N

International Chemical Identifier (InChI)

InChI=1S/B8O13.2Na.4H2O/c9-1-13-5-18-6(14-2-10)20-8-17-4(12)15-3(11)16-7(19-5)21-8;;;;;;/h;;;4*1H2/q-2;2*+1;;;;

2D structure diagram/image available?

Yes

General status

Pesticide type

Insecticide, Fungicide, Herbicide, Other substance

Other constituent type

Wood preservative

Substance group

Inorganic compound

Minimum active substance purity

>97.5%

Known relevant impurities

None declared in dossier prepared for Directive 98/8/EC

Substance origin

Natural

Mode of action

Mechanism depends on action: antifeed for insects distrupting insect enzyme & digestive systems

CAS RN

12280-03-4

EC number

234-541-0

CIPAC number

US EPA chemical code

011103

PubChem CID

No data

Molecular mass

412.53

PIN (Preferred Identification Name)

IUPAC name

boric acid, disodium salt tetrahydrate

CAS name

disodium octaborate tetrahydrate

Other status information

Biocide

Relevant Environmental Water Quality Standards

Herbicide Resistance Classification (HRAC)

Not applicable

Herbicide Resistance Classification (WSSA)

Not applicable

Insecticide Resistance Classification (IRAC)

Not applicable

Fungicide Resistance Classification (FRAC)

Not applicable

Examples of recorded resistance

Physical state

White, odourless powder

Related substances & organisms

boric acid

zinc borate

borax

Formulations

Property

Value

Example manufacturers & suppliers of products using this active now or historically

Boracare, Tim-Bor, Borathor, Termite Prufe, Board Defense

Example products using this active

Formulation and application details

As a wood preservative it is supplied in formulations suitable for application via vacuum pressure, dipping, injection and spraying

ENVIRONMENTAL FATE

Property

Value

Source; quality score; and other information

Interpretation

Solubility - In water at 20 °C (mg l⁻¹)

223650

High

Solubility - In organic solvents at 20 °C (mg l⁻¹)

Melting point (°C)

803

Boiling point (°C)

Degradation point (°C)

Flashpoint (°C)

Not expected to self-ignite; Not highly flammable

Octanol-water partition coefficient at pH 7, 20 °C

Log P

Bulk density (g ml⁻¹)

1.874

at 22 °C

Dissociation constant pKa) at 25 °C

9.0

Data for boric acid @ 25 DegC

Vapour pressure at 20 °C (mPa)

1.0 X 10^-02

Low volatility

Henry's law constant at 25 °C (Pa m³ mol⁻¹)

Maximum UV-vis absorption L mol⁻¹ cm⁻¹

No absorption maxima found in range 190-500nm.

Surface tension (mN m⁻¹)

Degradation

Property

Value

Source; quality score; and other information

Interpretation

General biodegradability

Soil degradation (days) (aerobic)

DT₅₀ (typical)

DT₅₀ (lab at 20 °C)

DT₅₀ (field)

DT₉₀ (lab at 20 °C)

DT₉₀ (field)

DT₅₀ modelling endpoint

Note

Dissipation rate RL₅₀ on plant matrix

Value

Note

Dissipation rate RL₅₀ on and in plant matrix

Value

Note

Aqueous photolysis DT₅₀ (days) at pH 7

Value

Stable

Note

Stable at all environmentally relevant pHs

Aqueous hydrolysis DT₅₀ (days) at 20 °C and pH 7

Value

Stable

Note

Stable at all environmentally relevant pHs

Water-sediment DT₅₀ (days)

Water phase only DT₅₀ (days)

Soil adsorption and mobility

Property

Value

Source; quality score; and other information

Interpretation

Linear

K_d

K_oc

Notes and range

Freundlich

K_f

2.6

K_foc

¹/_n

0.83

Notes and range

EU Dossier K_f range 0.4-8.41, ¹/_n range 0.726-0.955

pH sensitivity

Fate indices

Property

Value

Source; quality score; and other information

Interpretation

GUS leaching potential index

SCI-GROW groundwater index (μg l⁻¹) for a 1 kg ha⁻¹ or 1 l ha⁻¹ application rate

Value

Cannot be calculated

Note

Potential for particle bound transport index

Potential for loss via drain flow

Key metabolites

Metabolite

Formation medium

Estimated maximum occurrence fraction

1107/2009 relevancy

boric acid

Soil

ECOTOXICOLOGY

Property

Value

Source; quality score; and other information

Interpretation

Bio-concentration factor

BCF (l kg⁻¹)

CT₅₀ (days)

Mammals - Acute oral LD₅₀ (mg kg⁻¹)

> 2000

Rat

Low

Mammals - Short term dietary NOEL

(mg kg⁻¹)

(ppm diet)

Mammals - Chronic 21d NOAEL (mg kg⁻¹ bw d⁻¹)

Birds - Acute LD₅₀ (mg kg⁻¹)

> 527

Colinus virginianus as mg B/kg

Moderate

Birds - Short term dietary (LC₅₀/LD₅₀)

> 983 mg B kg bw⁻¹ day⁻¹

Colinus virginianus

Birds - Chronic 21d NOEL (mg kg⁻¹ bw d⁻¹)

Fish - Acute 96 hour LC₅₀ (mg l⁻¹)

125

Catostomus latipinnis as mg B/litre

Low

Fish - Chronic 21 day NOEC (mg l⁻¹)

1.8

Danio rerio 34 day as mg B/litre

Moderate

Aquatic invertebrates - Acute 48 hour EC₅₀ (mg l⁻¹)

141

Daphnia magna as mg B/litre

Low

Aquatic invertebrates - Chronic 21 day NOEC (mg l⁻¹)

Daphnia magna 21 day as mg B/litre

Moderate

Aquatic crustaceans - Acute 96 hour LC₅₀ (mg l⁻¹)

Sediment dwelling organisms - Acute 96 hour LC₅₀ (mg l⁻¹)

Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l⁻¹)

Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg⁻¹)

Aquatic plants - Acute 7 day EC₅₀, biomass (mg l⁻¹)

Non-target plants

Algae - Acute 72 hour EC₅₀, growth (mg l⁻¹)

Algae - Chronic 96 hour NOEC, growth (mg l⁻¹)

17.5

Selenastrum capricornutum 75hr as mg B/litre

Low

Honeybees (Apis spp.)

Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

> 362

Low

Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Unknown mode acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Bumblebees (Bombus spp.)

Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Mason bees (Osmia spp.)

Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Other pollinators (1)

Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)

Mode of exposure

Other pollinators (2)

Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)

Mode of exposure

Earthworms - Acute 14 day LC₅₀ (mg kg⁻¹)

473

Lumbricus terrestris as mg B/kg

Moderate

Earthworms - Chronic NOEC, reproduction (mg kg⁻¹)

Eisenia andrei as mg B/kg

Moderate

Other soil macro-organisms

Acute LC₅₀ (mg kg⁻¹)

Chronic NOEC (mg kg⁻¹)

Other arthropod (1)

LR₅₀ g ha⁻¹

% Effect

Other arthropod (2)

LR₅₀ g ha⁻¹

% Effect

Soil micro-organisms

Mesocosm study data

NOEAEC mg l⁻¹

HUMAN HEALTH AND PROTECTION

General

Property

Value

Source; quality score; and other information

Interpretation

Threshold of Toxicological Concern (Cramer Class)

High (class III)

Mammals - Acute oral LD₅₀ (mg kg⁻¹)

> 2000

Rat

Low

Mammals - Dermal LD₅₀ (mg kg⁻¹ body weight)

2000

Rat

Mammals - Inhalation LC₅₀ (mg l⁻¹)

> 2.0

Rat

Other Mammal toxicity endpoints

ADI - Acceptable Daily Intake (mg kg⁻¹ bw day⁻¹)

Not relevant

ARfD - Acute Reference Dose (mg kg⁻¹ bw day⁻¹)

Not relevant

AAOEL - Acute Acceptable Operator Exposure Level (mg kg⁻¹ bw day⁻¹)

AOEL - Acceptable Operator Exposure Level - Systemic (mg kg⁻¹ bw day⁻¹)

0.1

Rat SF=100

Dermal penetration studies (%)

Dangerous Substances Directive 76/464

Exposure Routes

Public

Occupational

European MRLs

EU MRL pesticide database

Drinking Water Standards

Drinking Water MAC (μg l⁻¹)

Health issues

Specific human health issues

Carcinogen

Genotoxic

Endocrine disruptor

; ; ; ;

Reproduction / development effects

Acetyl cholinesterase inhibitor

Neurotoxicant

Respiratory tract irritant

Skin irritant

Skin sensitiser

No data found

Eye irritant

Phototoxicant

No data found

General human health issues

Slightly toxic, may cause gastro-intestinal problems
May cause metabolism disorders
Possible testes toxicant

Handling issues

Property

Value and interpretation

General

Flame retardant- non-flammable
Not explosive or oxidising

CLP classification 2013

EC Risk Classification

T - Toxic: R60, R61

EC Safety Classification

WHO Classification

NL (Not listed)

UN Number

Not regulated

Waste disposal & packaging

TRANSLATIONS

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disodium octaborate tetrahydrate

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Record last updated:	18/01/2021
Contact:	aeru@herts.ac.uk
Please cite as:	Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242