Dimoxystrobin (Ref: BAS 505F)

Dimoxystrobin (Ref: BAS 505F)	Last updated: 09/04/2025
(Not known by any other names)

SUMMARY

Dimoxystrobin is mainly used as a cereal fungicide. It has a low aqueous solubility and a low volatility. It can be persistent in both soil and water systems. It is highly toxic to earthworms and fish it tends to be classified as moderate to low for other species. Dimoxystrobin has a low oral mammalian toxicity and is an endocrine disruptor.

Data alerts

The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.

Environmental fate	Ecotoxicity	Human health
Environmental fate Moderate alert: Moderately persistent; GUS: Transition state; Drainflow: Moderately mobile; Potential for particle bound transport: Medium	Ecotoxicity High alert: Fish acute ecotoxicity: High; Daphnia acute ecotoxicity: High; Earthworms chronic ecotoxicity: High	Human health Moderate alert: Mammals chronic toxicity: Moderate; Possible Carcinogen; Endocrine disrupter; Reproduction/development effects

GENERAL INFORMATION

Description

A fungicide used for disease control in cereals and some other crops

Example pests controlled

Brown rust; Ear blight; Stem rot; Stem canker; Dark leaf and pod spot; Light leaf spot

Example applications

Wheat; Oilseed rape; Turnip rape; Sunflower; Mustard seed

Efficacy & activity

Availability status

Current

Introduction & key dates

2003, introduced

GB regulatory status

GB COPR regulatory status

Approved

Date COPR inclusion expires

31/01/2028

GB LERAP status

Check label - may vary with formulation

EC Regulation 1107/2009 (repealing 91/414)

EC Regulation 1107/2009 status

Not approved

Dossier rapporteur/co-rapporteur

Hungary/Ireland

Date EC 1107/2009 inclusion expires

EU Candidate for substitution (CfS)

Yes - low ADI / ARfD / AOEL; two 'Persistent-Bioaccumulative-Toxic' criteria; endocrine disrupting properties

Listed in EU database

Yes

Approved for use (✓) under EC 1107/2009 in the following EU Member States

ATAustria	BEBelgium	BGBulgaria	CYCyprus	CZCzech Republic	DEGermany	DKDenmark	EEEstonia	ELGreece
	✓
ESSpain	FIFinland	FRFrance	HRCroatia	HUHungary	IEIreland	ITItaly	LTLithuania	LULuxembourg

LVLatvia	MTMalta	NLNetherlands	PLPoland	PTPortugal	RORomania	SESweden	SISlovenia	SKSlovakia
								✓

Approved for use (✓) under EC 1107/2009 by Mutual Recognition of Authorisation and/or national regulations in the following EEA countries

ISIceland	NONorway

Additional information

Also used in

Chemical structure

Isomerism

Isomeric, existing in the E- and Z-forms. The E-isomer is dominant and accounts for around 88-98% of dimoxystrobin,

Chemical formula

C₁₉H₂₂N₂O₃

Canonical SMILES

CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC

Isomeric SMILES

CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2/C(=N\OC)/C(=O)NC

International Chemical Identifier key (InChIKey)

WXUZAHCNPWONDH-DYTRJAOYSA-N

International Chemical Identifier (InChI)

InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18+/f/h20H

2D structure diagram/image available?

Yes

General status

Pesticide type

Fungicide

Substance groups

Strobilurin fungicide; Amide fungicide

Minimum active substance purity

994 g kg⁻¹

Known relevant impurities

EU 2023 dossier - None declared

Substance origin

Synthetic

Mode of action

Protectant, curative and translaminar. Respiration inhibitor (QoL fungicide).

CAS RN

149961-52-4

EC number

604-712-8

CIPAC number

739

US EPA chemical code

PubChem CID

10936292

CLP index number

616-164-00-7

Molecular mass

326.39

PIN (Preferred Identification Name)

(2E)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide

IUPAC name

(E)-2-(methoxyimino)-N-methyl-2-[a-(2,5-xylyloxy)-o-tolyl]acetamide

CAS name

(αE)-2-[(2,5-dimethylphenoxy)methyl]-α-(methoxyimino)-N-methylbenzeneacetamide

Other status information

PAN Listed as Highly Hazardous Chemical

Relevant Environmental Water Quality Standards

Herbicide Resistance Class (HRAC MoA class)

Not applicable

Herbicide Resistance Class (WSSA MoA class)

Not applicable

Insecticide Resistance Class (IRAC MoA class)

Not applicable

Fungicide Resistance Class (FRAC MOA class)

Examples of recorded resistance

Physical state

White crystalline solid

Formulations

Property

Value

Example manufacturers & suppliers of products using this active now or historically

BASF

Example products using this active

Swing-Gold
Pictor

Formulation and application details

Often available as a suspension concentrate comprising of dimoxystrobin and other active substances.

ENVIRONMENTAL FATE

Property

Value

Source; quality score; and other information

Interpretation

Solubility - In water at 20 °C (mg l⁻¹)

4.3

Low

Solubility - In organic solvents at 20 °C (mg l⁻¹)

73420

Acetone

22500

Toluene

21710

Methanol

44320

Ethyl acetate

Melting point (°C)

138.1

Boiling point (°C)

Decomposes before boiling

Degradation point (°C)

300

Flashpoint (°C)

Octanol-water partition coefficient at pH 7, 20 °C

3.89 X 10⁰³

Calculated

Log P

3.59

High

Fat solubility of residues

Solubility

Soluble

Data type

Regulatory data

Density (g ml⁻¹)

1.24

Dissociation constant pKa) at 25 °C

Not applicable

No dissociation

Vapour pressure at 20 °C (mPa)

6.00 X 10^-06

Low volatility

Henry's law constant at 25 °C (Pa m³ mol⁻¹)

5.9 X 10^-05

Non-volatile

Volatilisation as max % of applied dose lost

From plant surface

24 hr

Volatilisation is not considered critical for air pollution

From soil surface

24 hr

Volatilisation is not considered critical for air pollution

Maximum UV-vis absorption L mol⁻¹ cm⁻¹

205nm = 3000, 254nm = 4800, 290nm = 290, No absorbance maximum >290nm

Surface tension (mN m⁻¹)

64.3

at 20°C 0.5%w/w

Degradation

Property

Value

Source; quality score; and other information

Interpretation

General biodegradability

Soil degradation (days) (aerobic)

DT₅₀ (typical)

233.2

Persistent

DT₅₀ (lab at 20 °C)

232.2

Persistent

DT₅₀ (field)

48.5

Moderately persistent

DT₉₀ (lab at 20 °C)

826

Very persistent

DT₉₀ (field)

799

DT₅₀ modelling endpoint

Note

EU 2023 dossier lab studies DT₅₀ (normalised) range 124.7-331.8 days, DT₉₀ (measured) range 423.1->1000 days, Soils=7; Field studies DT₅₀ (measured) range 2.4-184.7 days, DT₉₀ (measured) range 283.2->1000 days, Soils=11

Dissipation rate RL₅₀ (days) on plant matrix

Value

Note

Dissipation rate RL₅₀ (days) on and in plant matrix

Value

Note

Aqueous photolysis DT₅₀ (days) at pH 7

Value

Stable

Note

Aqueous hydrolysis DT₅₀ (days) at 20 °C and pH 7

Value

Stable

Note

Stable pH 4 to pH 9 over 30 days, up to 50 °C

Water-sediment DT₅₀ (days)

Water phase only DT₅₀ (days)

15.3

Slow

Sediment phase only DT₅₀ (days)

Air degradation

As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below.

Decay in stored produce DT₅₀

Soil adsorption and mobility

Property

Value

Source; quality score; and other information

Interpretation

Linear

K_d (mL g⁻¹)

K_oc (mL g⁻¹)

Notes and range

Freundlich

K_f (mL g⁻¹)

4.85

Moderately mobile

K_foc (mL g⁻¹)

382.5

¹/_n

0.942

Notes and range

EU 2023 dossier kf range 1.82-9.14 mL g⁻¹, K_foc range 195.8-593.9 mL g⁻¹, ¹/_n range 0.902-0.990, Soils=7

pH sensitivity

Fate indices

Property

Value

Source; quality score; and other information

Interpretation

GUS leaching potential index

2.39

Calculated

Transition state

SCI-GROW groundwater index (μg l⁻¹) for a 1 kg ha⁻¹ or 1 l ha⁻¹ application rate

Value

1.32 X 10^-01

Calculated

Note

Potential for particle bound transport index

Medium

Calculated

Potential for loss via drain flow

Moderately mobile

Calculated

Photochemical oxidative DT₅₀ (hrs) as indicator of long-range air transport risk

1.48

Calculated using the Atkinson method. Assumed 1.5E+06 OH/cm³, 12 hr

Below the level of concern for long-range air transport

Bio-concentration factor

BCF (l kg⁻¹)

Low potential

CT₅₀ (days)

0.5

Known soil metabolites

Metabolite

Major/Minor fraction

$Click here for further information on Major/Minor fraction$

Estimated maximum occurrence fraction

Notes

(E-O-(2-hydroxycarbonyl-5-methyl)phenoxymethyl)-2-methoxyimino-N-methylphenyl acetamide (Ref: BF 505-7)

Minor fraction

BASF verified

(E-O-(5-hydroxycarbonyl-2-methyl)phenoxymethyl)-2-methoxyimino-N-methylphenyl acetamide (Ref: BF 505-8)

Major fraction

0.130

BASF verified

(E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide (Ref: BF 505-1)

Photolysis

Known groundwater metabolites

Metabolite

EC SANCO/221/2000 relevancy

ADI (mg kg⁻¹ bodyweight day⁻¹)

WHO drinking water guidance value (μg L⁻¹ day⁻¹)

(E-O-(2-hydroxycarbonyl-5-methyl)phenoxymethyl)-2-methoxyimino-N-methylphenyl acetamide (Ref: BF 505-7)

Not relevant

0.004

(E-O-(5-hydroxycarbonyl-2-methyl)phenoxymethyl)-2-methoxyimino-N-methylphenyl acetamide (Ref: BF 505-8)

Relevant

0.004

Other known metabolites

Metabolite name and reference

Aliases

Formation medium / Rate

Estimated maximum occurrence fraction

(2E)-2-{2-[(5-carboxy-4-hydroxy-2-methylphenoxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide

505M76

Animal (Tissue, Milk)

(E)-O-(2,5-dimethyl-4-hydroxy phenoxymethyl)-2-methoxyimino-N-methylphenylacetamide

505M02

Animal (Tissue, Milk)

4-({2-[(1E)-N-methoxy-2-(methylamino)-2-oxoethanimidoyl] benzyl}oxy)-2,5-dimethylphenylglucopyranosiduronic acid

505M78

Animal (Liver, Fat)

ECOTOXICOLOGY

Terrestrial ecotoxicology

Property

Value

Source; quality score; and other information

Interpretation

Mammals - Acute oral LD₅₀ (mg kg⁻¹)

> 5000

Rat

Low

Mammals - Short term dietary NOEL

(mg kg⁻¹)

Rat

High

(ppm diet)

Mammals - Chronic 21d NOAEL (mg kg⁻¹ bw d⁻¹)

136

Rat Reproductive NOAEL

Moderate

Birds - Acute LD₅₀ (mg kg⁻¹)

> 2000

Colinus virginianus

Low

Birds - Short term dietary (LC₅₀/LD₅₀)

> 1043 mg kg bw⁻¹ day⁻¹

Colinus virginianus

Birds - Chronic 21d NOEL (mg kg⁻¹ bw d⁻¹)

Anas platyrhynchos NOEC

Moderate

Earthworms - Acute 14 day LC₅₀ (mg kg⁻¹)

23.65

Eisenia foetida

Moderate

Earthworms - Chronic NOEC, reproduction (mg kg⁻¹)

0.089

Eisenia foetida

High

Soil micro-organisms

Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect

Dose: 20 kg ha⁻¹ 28 Day

Collembola

Acute LC₅₀ (mg kg⁻¹)

Chronic NOEC (mg kg⁻¹)

Non-target plants

Honeybees (Apis spp.)

Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

> 100

Apis mellifera

Low

Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

> 79.4

Apis mellifera

Moderate

Unknown mode acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Chronic

Notes

Bumblebees (Bombus spp.)

Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Mason bees (Osmia spp.)

Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)

Other bee species (1)

Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)

Mode of exposure

Other bee species (2)

Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)

Mode of exposure

Beneficial insects (Ladybirds)

Beneficial insects (Lacewings)

Beneficial insects (Parasitic wasps)

>30% Mortality at dose 0.2 kg ha⁻¹

Aphidius rhopalosiphi Adult

Beneficial insects (Predatory mites) as Mortality LR₅₀ g ha⁻¹

> 0.084

Typhlodromus pyri Adult

Beneficial insects (Ground beetles)

>30% Mortality at dose 0.2 kg ha⁻¹

Poecilus cupreus

Aquatic ecotoxicology

Property

Value

Source; quality score; and other information

Interpretation

Temperate Freshwater Fish - Acute 96 hour LC₅₀ (mg l⁻¹)

0.0434

Oncorhynchus mykiss

High

Temperate Freshwater Fish - Chronic 21 day NOEC (mg l⁻¹)

0.01

Oncorhynchus mykiss 28 day

Moderate

Tropical Freshwater Fish - Acute 96 hour LC₅₀ (mg l⁻¹)

Temperate Freshwater Aquatic invertebrates - Acute 48 hour EC₅₀ (mg l⁻¹)

0.0394

Daphnia magna

High

Temperate Freshwater Aquatic invertebrates - Chronic 21 day NOEC (mg l⁻¹)

0.0125

Daphnia magna

Moderate

Tropical Freshwater Aquatic invertebrates - Acute 48 hour EC₅₀ (mg l⁻¹)

Aquatic crustaceans - Acute 96 hour LC₅₀ (mg l⁻¹)

Sediment dwelling organisms - Acute 96 hour LC₅₀ (mg l⁻¹)

Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l⁻¹)

0.01

Chironomus riparius

Moderate

Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg⁻¹)

Aquatic plants (free-floating, growth) - Acute 7 day EC₅₀, biomass (mg l⁻¹)

Aquatic plants (rooted, growth) - Acute 14 day EC₅₀, biomass (mg l⁻¹)

Algae - Acute 72 hour EC₅₀, growth (mg l⁻¹)

0.153

Pseudokirchneriella subcapitata

Moderate

Algae - Chronic 96 hour NOEC, growth (mg l⁻¹)

Mesocosm study data

NOEAEC mg l⁻¹

0.005

Aquatic invertebrates Algae

NOEAEC mg l⁻¹

Marine bivalves

HUMAN HEALTH AND PROTECTION

General

Property

Value

Source; quality score; and other information

Interpretation

Threshold of Toxicological Concern (Cramer Class)

High (class III)

Mammals - Acute oral LD₅₀ (mg kg⁻¹)

> 5000

Rat

Low

Mammals - Dermal LD₅₀ (mg kg⁻¹ body weight)

2000

Rat

Mammals - Inhalation LC₅₀ (mg l⁻¹)

1.3

Rat 4hr (head & nose)

Other Mammal toxicity endpoints

ADI - Acceptable Daily Intake (mg kg⁻¹ bw day⁻¹)

0.015

Rat SF=1000

ARfD - Acute Reference Dose (mg kg⁻¹ bw day⁻¹)

0.04

Rat SF=200

AAOEL - Acute Acceptable Operator Exposure Level (mg kg⁻¹ bw day⁻¹)

0.018

Rat SF=100

AOEL - Acceptable Operator Exposure Level - Systemic (mg kg⁻¹ bw day⁻¹)

0.007

Rat SF=100

Dermal penetration studies (%)

1-13

concentration dependent

Dangerous Substances Directive 76/464

Exposure Routes

Public

Minimal risk from dietary exposure
Risk assessment indicates ARfD would not normally be execeeded

Occupational

MRLs

European

EU MRL pesticide database

Great Britain

GB MRL Register

Notes

Drinking Water Standards

Drinking Water MAC (μg l⁻¹)

0.1

EU Dir 89/778/EC limit; Calc MAC=60.0 µg l⁻¹

Mammalian dose elimination route and rate

Rapid and extensive elimination via faeces (65-83%)

Health issues

Specific human health issues

Carcinogen

Genotoxic

Endocrine disruptor

; ; ; ;

Reproduction / development effects

Acetyl cholinesterase inhibitor

Neurotoxicant

Respiratory tract irritant

Skin irritant

Skin sensitiser

No data found

Eye irritant

Phototoxicant

General human health issues

Harmful if inhaled
CLP data - suspected carcingen
May damage duodenal

Handling issues

Property

Value and interpretation

General

Not explosive or oxidising
IMDG Transport Hazard Class 9
Not expected to auto-ignite; Not highly flammable

CLP classification 2013

Health: H332, H351, H361d
Environment: H400, H410

WHO Classification

Not listed (Not listed)

UN Number

UN3077

Waste disposal & packaging

Packaging Group III (minor danger)

Shelf-life, storage, stability and reactivity

Chemically stable under standard ambient conditions

TRANSLATIONS

Language

Name

English

dimoxystrobin

French

dimoxystrobine

German

Dimoxystrobin

Danish

dimoxystrobin

Italian

dimoxystrobin

Spanish

dimoxistrobin

Greek

Polish

dimoksystrobina

Swedish

Hungarian

Dutch

Norwegian

Record last updated:	09/04/2025
Contact:	aeru@herts.ac.uk
Please cite as:	Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242