Dinoseb (Ref: HOE 26150) |
![]() Last updated: 16/01/2021 |
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(Also known as: DNBP; dinosebe; dinitro-general; DN 289) |
SUMMARY |
Dinoseb is a banned herbicide that was once widely used. It has a moderate aqueous solubility, is volatile and has a high potential for leaching to groundwater. It is not generally persistent in soil systems but can be persistent in water. It is highly toxic to mammals and may cause development/reproduction effects. Dinoseb is also a know irritant. It is highly toxic to birds, moderately toxic to fish but presents less of a risk to honeybees. |
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An obsolete dinitrophenol herbicide that was used for post-emergence weed control in a variety of crops including cereals, vegetables and some soft fruit | |
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Crabgrass; Barnyardgrass; Pigweed; Lambsquarters; Foxtails; Sorrel | |
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Soybeans; Cereals; Cotton; Fruit including citrus, grapes, bluebrries, currants, gooseberries; Nuts; Lucerne | |
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Obsolete, Banned | |
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1945, first reported |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Chemical structure |
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A chiral molecule | |
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C₁₀H₁₂N₂O₅ | |
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CCC(C)C1=CC(=CC(=C1O)[N+](=O)[O-])[N+](=O)[O-] | |
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No data | |
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OWZPCEFYPSAJFR-UHFFFAOYSA-N | |
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InChI=1S/C10H12N2O5/c1-3-6(2)8-4-7(11(14)15)5-9(10(8)13)12(16)17/h4-6,13H,3H2,1-2H3 | |
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Yes |
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Common Name | Relationship | Link |
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dinoseb | Unstated isomer | ![]() |
General status |
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Herbicide | |
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Dinitrophenol | |
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>95% | |
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Synthetic | |
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Contact. Inhibits respiratory electron transport and is an uncoupler of oxidative phosphorylation via disruption of proton gradient - membrane disruption. | |
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88-85-7 | |
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201-861-7 | |
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46 | |
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037505 | |
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6950 | |
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609-025-00-7 | |
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240.22 | |
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rac-2-[(2R)-butan-2-yl]-4,6-dinitrophenol | |
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(RS)-2-sec-butyl-4,6-dinitrophenol | |
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2-(1-methylpropyl)-4,6-dinitrophenol | |
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Chemical subject to PIC regulations; Marine Pollutant; Rotterdam Convention (Class O) | |
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M | |
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24 | |
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Not applicable | |
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Not applicable | |
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Dark reddish brown solid or orange viscous liquid depending upon temperature |
Formulations |
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Available in a variety of formulations including soluble liquids and emulsifiable concentrates. |
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52 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
Moderate | ||||||||
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480000 | R3 R = Peer reviewed scientific publications Ethanol3 = Unverified data of known source |
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270000 | L3 L = Pesticide manuals and hard copy reference books / other sources Ethanol3 = Unverified data of known source |
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38 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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177 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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1.95 X 1002 | Calculated | - | |||||||
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2.29 | H4 H = The US ARS pesticide properties database (click here ) 4 = Verified data |
Low | ||||||||
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1.35 | Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source |
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4.62 | DW4 DW = Don Wauchope personal database for Pka data: Wauchope, R. D. and Edwards, J. Dissociation constants for pesticide active ingredients: a database and comparison with predicted values. MS in preparation 4 = Verified data |
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Weak acid | |||||||||||
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6.7 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
Moderately volatile | ||||||||
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6.01 X 10-04 | H4 H = The US ARS pesticide properties database (click here ) 4 = Verified data |
Non-volatile | ||||||||
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Degradation |
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18 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
Non-persistent | |||||||
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30 | Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source |
Moderately persistent | ||||||||
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General literature data indicates DT₅₀ of 2 to 6 weeks | ||||||||||
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Stable | T4 T = UN EPFA database 4 = Verified data |
Stable | |||||||
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Soil adsorption and mobility |
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- | H3 H = The US ARS pesticide properties database (click here ) 3 = Unverified data of known source |
Mobile | |||||||
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30 | ||||||||||
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Other sources: 117-123 mL g⁻¹ (R3) | ||||||||||
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Fate indices |
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3.73 | Calculated | High leachability | ||||||||||||||||||||||||||
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6.36 X 10-01 | Calculated | - | |||||||||||||||||||||||||
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Low | Calculated | - | ||||||||||||||||||||||||||
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Mobile | Calculated | - |
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1.8 | R3 R = Peer reviewed scientific publications (whole body)3 = Unverified data of known source |
Low potential | |||||||
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Not available | - | |||||||||
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25 | G4 G = Extension Toxicology network database EXTOXNET (click here ) Rat4 = Verified data |
High | ||||||||
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9.5 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Anas platyrhynchos3 = Unverified data of known source |
High | ||||||||
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0.044 | G3 G = Extension Toxicology network database EXTOXNET (click here ) Salmonidae3 = Unverified data of known source |
High | ||||||||
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0.059 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Pimephales promelas 32 day3 = Unverified data of known source |
Moderate | ||||||||
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0.24 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna4 = Verified data |
Moderate | ||||||||
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0.170 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Americamysis bahia4 = Verified data |
Moderate | ||||||||
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1.201 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Chlamydomonas moewusii 7 day3 = Unverified data of known source |
Low | ||||||||
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Highly toxic | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Highly toxic | ||||||||
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General |
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High (class III) | - | - | ||||||||
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25 | G4 G = Extension Toxicology network database EXTOXNET (click here ) Rat4 = Verified data |
High | ||||||||
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0.0011 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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Minimal risk due to substance being obsolete | |||||||||
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Readily absorbed through the skin - PPE/PPC required | ||||||||||
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Health issues |
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Highly hazardous USEPA - possible human carcinogen |
Handling issues |
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An oxidising agent | |||
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Health: H301, H311, H319, H360Df Environment: H400, H410 |
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Reproduction risk category 2 and 3: R62, R61 T - Toxic: R24/25 Xi - Irritant: R36 H - Handling risks: R44 N - Dangerous for the environment: R50, R53 |
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S45, S53, S60, S61 | |||
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Ib (Highly hazardous / Highly hazardous) | |||
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dinoseb | ||
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dinosèbe | ||
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Dinoseb | ||
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dinoseb | ||
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dinoseb | ||
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dinoseb | ||
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dinoseb | ||
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dinoseb | ||
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dinoseb |
Record last updated: | 16/01/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |