Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides
GET ADDITIONAL DATA HERE!

dodine (Ref: BAS 365F)
** cytrex ** doguadine ** tsitrex ** CL 7521 ** carpene ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for dodine

Description: A fungicide used to control scab, leaf spot and other foliar diseases. Also an effective algal growth inhibitor useful in non-agricultural applications.

Example pests controlled: Scab, Leaf spot, Brown rot; Blossom rot; Fusarium wilt; Downey mildew

Example applications: Tree fruit including apple, pear, peach, cherry; Strawberries; Walnuts; Sycamore; Onions; Roses

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1957, first reported

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Spain/Germany
Date inclusion expires 31/05/2021
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism None
Chemical formula C15H33N3O2
Canonical SMILES CCCCCCCCCCCCN=C(N)N.CC(=O)O
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) YIKWKLYQRFRGPM-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide
Substance group Guanidine
Minimum active substance purity 950 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Systemic with protectant and eradicant action
CAS RN 2439-10-3
EC number 219-459-5
CIPAC number 101
US EPA chemical code 044301
PubChem CID 17110
Molecular mass (g mol-1) 287.44
PIN (Preferred Identification Name) N-dodecylguanidinium acetate
IUPAC name 1-dodecylguanidinium acetate
CAS name dodecylguanidine monoacetate
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) M7
Examples of recorded resistance -
Physical state Colourless to yellow fine waxy powder. Product may be liquid.
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Clayton
  • Greencrop
  • Hermoo
Example products using this active
  • Dodifun 400SC
  • Radspor L
  • Syllit 400SC
UK LERAP status None
Formulation and application details Often supplied as an emulsifiable concentrate or wettable powder.


ENVIRONMENTAL FATE

for dodine

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 930 A5 High
Solubility - In organic solvents at 20oC (mg l-1) 18 A5 - n-Heptane -
4 A5 - Xylene -
48 A5 - Acetone -
57000 A5 - Ethanol -
Melting point (oC) 132.2 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 200.5 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 1.78 X 1001 Calculated -
Log P 1.25 A5 Low
Bulk density (g ml-1)/Specific gravity - - -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 5.49 X 10-03 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 1.69 X 10-06 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -1.79 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 200nm= 2600, 290nm = 1.5 A5 -
Surface tension (mN m-1) 50.6 A5 at 20oC -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 4.7 A5 Non-persistent
DT50 (lab at 20oC) 4.8 A5 Non-persistent
DT50 (field) 13.3 A5 Non-persistent
DT90 (lab at 20oC) 17.8 A5 -
DT90 (field) 60.1 A5 -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 2.6-8.2 days, DT90 range 10.5-27.2 days; field studies DT50 range 6.7-18.6; DT90 range 22.1-108.3 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value 4.0 R4 -
Note Published literature RL50 range 3.6-4.5 days, apple, various matrices, n=2
Aqueous photolysis DT50 (days) at pH 7 Value 12.6 A5 Moderately fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 914 A5 Very persistent
Note pH sensitive: DT50 576 days at pH 5, 1198 days at pH 9, all at 25 deg C
Water-sediment DT50 (days) 0.33 A5 Fast
Water phase only DT50 (days) 0.18 A5 Fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd 10472 A4 Non-mobile
Koc 4236500
Notes and range EU dossier Kd range 2202-18019 mL/g, Koc range 5.51E05 - 1.29E07 mL/g, Soils=4
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity No

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
- urea Plant - -
- dodecyl guanidine carboxylic acid Animal - -
- octylguanidine carboxylic acid Animal - -
- hexylguanidine carboxylic acid Animal - -
(Ref: Dodine-M01) guanidine Plant 0.36 -
(Ref: Dodine-M02) hydroxydodecylguanidine Animal (Urinary) 0.23 -


ECOTOXICOLOGY

for dodine

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 16 F4 Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 851 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 800 -
Birds - Acute LD50 (mg kg-1) 857 A5 Anas platyrhynchos Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.57 F4 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.099 A4 Pimephales promelas 30day Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.018 A5 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.0044 A5 Daphnia magna High
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 1.7 F3 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) 3.2 A5 Chironomus riparius Moderate
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.0028 A4 Pseudokirchneriella subcapitata High
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 100 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 200 A5 Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) 547 A5 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 171 A5 Eisenia foetida Low
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 1800 >, 48 hour
A5 Aphidius rhopalosiphi
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 7512 >, 7 day
A5 Typhlodromus pyri
-
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 9 kg ha-1, 28 days
-
Mesocosm study data NOEAEC mg l-1 0.041 A5 Aquatic invertebrates -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for dodine

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 851 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 0.45 A5 Rat (nose only, aerosol) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.1 A4 Dog, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.1 A4 Dog, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.045 A4 Rat, SF=100 -
Dermal penetration studies (%) 1.0 A5 -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public No unacceptable risks to bystanders identified
Occupational Possible risk to operators identified even with PPE
Harmful by inhalation
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; A5 Calc MAC=0.35 μg l-1 -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

General human health issues Highly toxic
Serious damage to eyes

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 Health: H302, H315, H319
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R22
Xi - Irritant: R36/38
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S26, S60, S61
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) I - Danger - Highly toxic
UN Number Usually 3077 or 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for dodine

Language Name
English dodine
French dodine
German Dodin
Danish dodine
Italian dodina
Spanish dodina
Greek dodine
Slovenian dodin
Polish dodyna
Swedish dodin
Hungarian dodine
Dutch dodine

Record last updated: Thursday 23 August 2018
Contact: aeru@herts.ac.uk