Afidopyropen (Ref: ME5343) |
![]() Last updated: 16/12/2020 |
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(Also known as: coprapidpen; BAS 440 I) |
SUMMARY |
Afidopyropen is a novel insecticide that does not have approval for use in the EU. It is moderately persistent in soil and water. It is moderately mobile and may leach to groundwaters. It has a favourable biodiversity toxcityl profile and is not highly toxic to bees. Whilst it has a low oral toxicity to mammals there are some conserns that afidopyropen may be carcinogenic. |
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A novel insecticide that is effective against sucking insects | |
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Aphids; Spidermites; Thrips; Psyllids; Mealybugs, Scale | |
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Fruit; Vegetables; Nuts; Cotton; ; Ornamentals | |
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Current | |
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2013 |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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USA; Australia |
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Chemical structure |
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Isomeric | |
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C₃₃H₃₉NO₉ | |
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CC12CCC(C(C1CC(C3(C2C(C4=C(O3)C=C(OC4=O)C5=CN=CC=C5)O)C)O)(C)COC(=O)C6CC6)OC(=O)C7CC7 | |
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C[C@]12CC[C@@H]([C@@]([C@@H]1C[C@@H]([C@@]3([C@@H]2[C@H](C4=C(O3)C=C(OC4=O)C5=CN=CC=C5)O)C)O)(C)COC(=O)C6CC6)OC(=O)C7CC7 | |
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LRZWFURXIMFONG-HRSIRGMGSA-N | |
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InChI=1S/C33H39NO9/c1-31-11-10-24(42-29(38)18-8-9-18)32(2,16-40-28(37)17-6-7-17)22(31)14-23(35)33(3)27(31)26(36)25-21(43-33)13-20(41-30(25)39)19-5-4-12-34-15-19/h4-5,12-13,15,17-18,22-24,26-27,35-36H,6-11,14,16H2,1-3H3/t22-,23+,24+,26+,27-,31+,32+,33-/m1/s1 | |
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Yes |
General status |
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Insecticide | |
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Pyropene | |
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Synthetic | |
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Disrupts insect feeding behaviour. A chlordotonal orgn TRPV (transient receptor potential vanilloid) channel modulatot | |
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915972-17-7 | |
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7969 | |
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54589430 | |
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593.7 | |
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((3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3-(cyclopropylcarbonyloxy)-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-6,12-dihydroxy-4,6a,12b-trimethyl-11-oxo-9-(3-pyridyl)-11H,12H-benzo(f)pyrano(4,3-b)chromen-4-yl)methyl cyclopropanecarboxylate | |
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((3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3-((cyclopropylcarbonyl)oxy)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-6,12-dihydroxy-4,6a,12b-trimethyl-11-oxo-9-(3-pyridinyl)-2H,11H-naphtho(2,1-b)pyrano(3,4-e)pyran-4-yl)methyl cyclopropanecarboxylate | |
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- | |
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Possible groundwater pollutants | |
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Not applicable | |
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Not applicable | |
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9D | |
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Not applicable | |
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The technical maaterial is a yellow powder |
Formulations |
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25.1 | E4 E = Manufacturers safety data sheets 4 = Verified data |
Low | ||||||||
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55400 | E4 E = Manufacturers safety data sheets Toluene4 = Verified data |
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500000 | E4 E = Manufacturers safety data sheets Methanol4 = Verified data |
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500000 | E4 E = Manufacturers safety data sheets Acetone4 = Verified data |
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500000 | E4 E = Manufacturers safety data sheets Ethyl acetate4 = Verified data |
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150 | E4 E = Manufacturers safety data sheets 4 = Verified data |
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Not expected to self-ignite; Not highly flammable | P4 P = Other governments and regulators 4 = Verified data |
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2.82 X 1003 | Calculated | - | |||||||
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3.45 | P4 P = Other governments and regulators 4 = Verified data |
High | ||||||||
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9,99 X 10-03 | P4 P = Other governments and regulators 4 = Verified data |
Low volatility | ||||||||
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2.34 X 10-04 | P4 P = Other governments and regulators 4 = Verified data |
Non-volatile | ||||||||
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Degradation |
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8.8 | E4 E = Manufacturers safety data sheets 4 = Verified data |
Non-persistent | |||||||
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8.8 | E4 E = Manufacturers safety data sheets 4 = Verified data |
Non-persistent | ||||||||
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General literature: aerobic DT₅₀ 2.7-18.6 days | ||||||||||
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Stable | P3 P = Other governments and regulators 3 = Unverified data of known source |
Stable | |||||||
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Stable at all environmntally relevant pH values | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Cannot be calculated | - | - | |||||||||||||||||||||||||
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> 2000 | E4 E = Manufacturers safety data sheets Rat4 = Verified data |
Low | ||||||||
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> 802 | E4 E = Manufacturers safety data sheets Colinus virginianus4 = Verified data |
Moderate | ||||||||
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> 18.3 | E4 E = Manufacturers safety data sheets Pimephales promelas4 = Verified data |
Moderate | ||||||||
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> 8.0 | E4 E = Manufacturers safety data sheets Daphnia magna4 = Verified data |
Moderate | ||||||||
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> 200 | E3 E = Manufacturers safety data sheets Apis mellifea3 = Unverified data of known source |
Low | |||||||
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> 100 | E3 E = Manufacturers safety data sheets Apis mellifera3 = Unverified data of known source |
Low | ||||||||
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> 1000 | E3 E = Manufacturers safety data sheets Eisenia foatida3 = Unverified data of known source |
Low | ||||||||
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General |
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High (class III) | - | - | ||||||||
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> 2000 | E4 E = Manufacturers safety data sheets Rat4 = Verified data |
Low | ||||||||
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2000 | E4 E = Manufacturers safety data sheets Rat4 = Verified data |
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> 5.48 | E4 E = Manufacturers safety data sheets Rat4 = Verified data |
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Health issues |
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No information available |
Handling issues |
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Not explosive or oxidising | |||
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NL (Not listed) | |||
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afidopyropen | ||
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afidopyropene | ||
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Record last updated: | 16/12/2020 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |