Endothal
Last updated: 16/01/2023
(Also known as: endothall; endothal acid)
Endothal is a selective, contact herbicide. It is highly soluble in water and semi-volatile. Based on its chemical properties it is not expected to leach to groundwater. It is generally non-persistent in soils. Endothal is highly toxic to mammals but is not expected to bioaccumulate. It is a recognised irritant. It is moderately toxic to fish and aquatic organisms but is less toxic to birds.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A erbicide, defoliant plant growth regulator and algicide used to control annual grasses, broad-leaved and aquatic weeds
Plankton; Pondweed; Coontail; Milfoil; Algae; Fathen; Chickweed
Aquatic situations; Sugarbeet; Spinach; Turf; Alfalfa; Potatoes; Cotton
-
Current
circa 1952
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Expired
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
A chiral molecule with 4 theoretical stereoisomers. The rel-(1R,2S,3R,4S)- isomer is the most effective herbicide.
C₈H₁₀O₅
C1CC2C(C(C1O2)C(=O)O)C(=O)O
No data
GXEKYRXVRROBEV-UHFFFAOYSA-N
InChI=1S/C8H10O5/c9-7(10)5-3-1-2-4(13-3)6(5)8(11)12/h3-6H,1-2H2,(H,9,10)(H,11,12)
Yes
Herbicide, Algicide, Plant Growth Regulator
Dicarboxylic acid
-
-
Synthetic
Selective, contact, absorbed through leaves and roots
145-73-3
205-660-5
154
038901
3225
607-150-00-1
186.16
(1E,2E,3E,4E)-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
-
-
R
31
Not applicable
Not applicable
-
Colourless to white crystals
Hydout Herbicide 273 Tribetol Des-I-Cate Aquathol
Usually supplied as an aquatic suspension or a granular formulation.
100000
High
280000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Methanol
-
76000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Dioxane
-
70000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
100
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Benzene
-
144
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
8.13 X 1001
Calculated
-
1.91
Low
-
-
-
-
-
-
1.43
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
3.4
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
pKa(2) 6.7
2.09 X 10-05
Low volatility
3.90 X 10-11
Non-volatile
-
-
-
-
-
-
-
5
Non-persistent
-
-
-
7
Non-persistent
-
-
-
-
-
-
-
-
-
Best available data
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Moderately mobile
85
Other sources: Koc 124 mL g⁻¹ (US3, DW3)
-
-
-
-
-
-
-
1.75
Calculated
Low leachability
1.22 X 10-02
Calculated
-
-
Low
Calculated
-
Moderately mobile
Calculated
-
0.4
Whole fish
Low potential
Not available
-
None
Terrestrial ecotoxicology
51
Rat
High
-
-
-
-
-
-
-
-
> 5000
Anas platyrhynchos
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 78
Oncorhynchus mykiss
Moderate
1.3
P3 P = Other governments and regulators 3 = Unverified data of known source
Pimephales promelas 31 day
Moderate
> 32.5
Daphnia magna
Moderate
< 2.2
Daphnia magna
Moderate
> 150
Americamysis bahia
Low
-
-
-
-
-
-
-
-
-
-
-
-
50
Pseudokirchneriella subcapitata 10 day
Low
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
51
Rat
High
2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rabbit
-
0.68
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
XNo, known not to cause a problem
?Possibly, status not identified
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
Toxic Corrosive effects on gastrointestinal tract
Not explected to autoignite, Not highly flammable
Health: H301, H312, H315, H319, H335
II (Moderately hazardous)
-
-
endothal
endothal
Endothal
endothal
endotal
endotal
endothal
endotal
-
-
endothal
Record last updated:
16/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242