phosametine (Ref: LS830556) ** huangcaoling ** Translations

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GENERAL INFORMATION
for phosametine

Description: An obsolete herbicide that was used to control grass and broad-leaved weeds in a range of cropping situations

Example pests controlled: Grass, Broad-leaved weeds

Example applications: Vines; Orchards; Cereals

Efficacy & activity: -

Availability status: Unknown

Introduction & key dates: -

EC Regulation 1107/2009 (repealing 91/414):

Status	Not approved
Dossier rapporteur/co-rapporteur	Not applicable
Date inclusion expires	Not applicable
EU Candidate for substitution (CfS)	Not applicable
Listed in EU database	Yes

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: China

Chemical structure:

Isomerism	-
Chemical formula	C5H13N2O6PS
Canonical SMILES	CN(C(=O)CNCP(=O)(O)O)S(=O)(=O)C
Isomeric SMILES	No data
International Chemical Identifier key (InChIKey)	HPDFFWOTIYEPLZ-UHFFFAOYSA-N
International Chemical Identifier (InChI)	InChI=1S/C5H13N2O6PS/c1-7(15(2,12)13)5(8)3-6-4-14(9,10)11/h6H,3-4H2,1-2H3,(H2,9,10,11)
Structure diagram/image available?	Yes

General status:

Pesticide type	Herbicide
Substance group	Organophosphate
Minimum active substance purity	-
Known relevant impurities	-
Substance origin	Synthetic
Mode of action	Enolpyruvylshikimate-2-phophate (EPSP) synthase inhibitor
CAS RN	98565-18-5
EC number	-
CIPAC number	-
US EPA chemical code	-
PubChem CID	163683
Molecular mass (g mol-1)	260.21
PIN (Preferred Identification Name)	(((2-(N-methylmethanesulfonamido)-2-oxoethyl)amino)methyl)phosphonic acid
IUPAC name	N-mesyl-N-methyl-2-(phosphonomethylamino)acetamide
CAS name	P-(((2-(methyl(methylsulfonyl)amino)-2-oxoethyl)amino)methyl)phosphonic acid
Other status information	-
Relevant Environmental Water Quality Standards	-
Herbicide Resistance Classification (HRAC)	-
Herbicide Resistance Classification (WSSA)	-
Insecticide Resistance Classification (IRAC)	Not applicable
Fungicide Resistance Classification (FRAC)	Not applicable
Examples of recorded resistance	-
Physical state	Crystalline solid
Related substances & organisms	-

Formulations:

Property	Value
Example manufacturers & suppliers of products using this active now or historically	Rhône-Poulenc Agrochimie
Example products using this active	-
UK LERAP status	No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details	Usually supplied as wettable granules.

ENVIRONMENTAL FATE
for phosametine

Property		Value	Source/Quality Score/Other Information	Interpretation
Solubility - In water at 20oC (mg l-1)		45000	L3	High
Solubility - In organic solvents at 20oC (mg l-1)		20000	L3 - Acetic acid	-
Melting point (oC)		213	L3	-
Boiling point (oC)		481	Q3	-
Degradation point (oC)		-	-	-
Flashpoint (oC)		244.6	Q3	-
Octanol-water partition coefficient at pH 7, 20oC	P	-	-	-
	Log P	-	-	-
Bulk density (g ml-1)/Specific gravity		1.582	Q3	-
Dissociation constant (pKa) at 25oC		-	-	-
		Note:
Vapour pressure at 20oC (mPa)		0.267	L3	Low volatility
Henry's law constant at 25oC (Pa m3 mol-1)		-	-	-
GUS leaching potential index		-	-	-
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate	Value	-	-	-
	Note	-
Potential for particle bound transport index		-	-	-
Maximum UV-vis absorption L mol-1 cm-1		-	-	-
Surface tension (mN m-1)		-	-	-

Degradation:

Property		Value	Source/Quality Score/Other Information	Interpretation
General biodegradability		-
Soil degradation (days) (aerobic)	DT50 (typical)	-	-	-
	DT50 (lab at 20oC)	-	-	-
	DT50 (field)	-	-	-
	DT90 (lab at 20oC)	-	-	-
	DT90 (field)	-	-	-
	DT50 modelling endpoint	-	-	-
	Note:	-
Dissipation rate RL50 on plant matrix	Value	-	-	-
	Note	-
Dissipation rate RL50 on and in plant matrix	Value	-	-	-
	Note	-
Aqueous photolysis DT50 (days) at pH 7	Value	-	-	-
	Note	-
Aqueous hydrolysis DT50 (days) at 20oC and pH 7	Value	-	-	-
	Note	-
Water-sediment DT50 (days)		-	-	-
Water phase only DT50 (days)		-	-	-

Soil adsorption and mobility:

Property		Value	Source/Quality Score/Other Information	Interpretation
Linear	Kd	-	-	-
	Koc	-
	Notes and range	-
Freundlich	Kf	-	-	-
	Kfoc	-
	1/n	-
	Notes and range	-
pH sensitivity		-

ECOTOXICOLOGY
for phosametine

Property		Value	Source/Quality Score/Other Information	Interpretation
Bio-concentration factor	BCF (l kg-1)	-	-	-
	CT50 (days)	-		-
Mammals - Acute oral LD50 (mg kg-1)		> 5000	Q3 Rat	Low
Mammals - Short term dietary NOEL	(mg kg-1)	-	-	-
	(ppm diet)	-		-
Birds - Acute LD50 (mg kg-1)		> 2150	L3 Colinus virginianus	Low
Birds - Short term dietary (LC50/LD50)		-	-	-
Fish - Acute 96 hour LC50 (mg l-1)		320	L3 Oncorhynchus mykiss	Low
Fish - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1)		-	-	-
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1)		-	-	-
Aquatic plants - Acute 7 day EC50, biomass (mg l-1)		-	-	-
Non-target plants		-	-	-
		-	-	-
Algae - Acute 72 hour EC50, growth (mg l-1)		-	-	-
Algae - Chronic 96 hour NOEC, growth (mg l-1)		-	-	-
Honeybees	Contact acute 48 hour LD50 (μg bee-1)	-	-	-
	Oral acute 48 hour LD50 (μg bee-1)	-	-	-
	Unknown mode acute 48 hour LD50 (μg bee-1)	-	-	-
Earthworms - Acute 14 day LC50 (mg kg-1)		-	-	-
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1)		-	-	-
Other soil macro-organisms - e.g. Collembola	LR50 / EC50 / NOEC / % Effect	-	-	-
Other arthropod (1)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Other arthropod (2)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Soil micro-organisms		-	-	-
Mesocosm study data	NOEAEC mg l-1	-	-	-
	NOEAEC mg l-1	-	-	-

HUMAN HEALTH AND PROTECTION
for phosametine

General:

Property		Value	Source/Quality Score/Other Information	Interpretation
Threshold of Toxicological Concern (Cramer Class)		High (class III)	-	-
Mammals - Acute oral LD50 (mg kg-1)		> 5000	Q3 Rat	Low
Mammals - Dermal LD50 (mg kg-1 body weight)		> 4000	L3 Rabbit	-
Mammals - Inhalation LC50 (mg l-1)		-	-	-
Other Mammal toxicity endpoints		-		-
ADI - Acceptable Daily Intake (mg kg-1bw day-1)		-	-	-
ARfD - Acute Reference Dose (mg kg-1bw day-1)		-	-	-
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1)		-	-	-
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1)		-	-	-
Dermal penetration studies (%)		-	-	-
Dangerous Substances Directive 76/464		-	-	-
Exposure Limits		-	-	-
Exposure Routes	Public	-
	Occupational	-
European MRLs		Click here for the EU MRL pesticide database
Drinking Water Standards		-	-	-
Drinking Water MAC (μg l-1)		-	-	-

Health issues:

Carcinogen	Mutagen	Endocrine disrupter	Reproduction / development effects	Cholinesterase inhibitor	Neurotoxicant
-	-	-	-		-
Respiratory tract irritant	Skin irritant	Skin sensitiser	Eye irritant	Phototoxicant
-	-	-	-	-
General human health issues		No information available

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:

Property		Value	Source/Quality Score/Other Information	Interpretation
General		When heated to decomposition it emits toxic vapors of NOx, POx, and SOx
CLP classification 2013		-
EC Risk Classification		-
EC Safety Classification		-
WHO Classification		-	-
US EPA Classification (formulation)		-	-
UN Number		-
Waste disposal & packaging		-

TRANSLATIONS
for phosametine

Language	Name
English	phosametine
French	-
German	-
Danish	-
Italian	-
Spanish	-
Greek	-
Slovenian	-
Polish	-
Swedish	-
Hungarian	-
Dutch	-

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Record last updated: Friday 01 June 2018
Contact: aeru@herts.ac.uk