Drazoxolon (Ref: PP781)
Last updated: 23/01/2023
(Not known by any other names)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
An obsolete oxazole foliar fungicide used to control fungal diseases on a variety of crops
Powdery mildew; Downy mildew; Foot rot; Root rot; Damping-off; Fusarium solani ; Rusts
Glasshouse crops; Blackcurrant; Peas; Ornamentals including roses
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Considered obsolete but may be available in some countries
1967, first reported
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
Isomeric existing in the cis- and trans-forms
C₁₀H₈ClN₃O₂
CC1=NOC(=O)C1=NNC2=CC=CC=C2Cl
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OOTHTARUZHONSW-UHFFFAOYSA-N
InChI=1S/C10H8ClN3O2/c1-6-9(10(15)16-14-6)13-12-8-5-3-2-4-7(8)11/h2-5,12H,1H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
drazoxolon
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Fungicide
Oxazole fungicide
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-
Synthetic
Protective and curative action.
5707-69-7
8039-90-5
227-197-8
301
-
9570206
650-008-00-9
237.6
(4E)-4-[(2-chlorophenyl)hydrazinylidene]-3-methyl-1,2-oxazol-5(4H)-one
(EZ)-4-(2-chlorophenylhydrazono)-3-methyl-1,2-oxazol-5(4H)-one
3-methyl-4,5-isoxazoledione 4-[(2-chlorophenyl)hydrazone]
-
-
Not applicable
Not applicable
Not applicable
Not known
-
Yellow coloured crystalline solid
ICI Plant Protection Zeneca Agrochemicals
Often supplied as a suspension concentrate and used as a seed dressing
10000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
10000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Ethanol
-
10000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Chloroform
-
167
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
3.98 X 1002
Calculated
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2.6
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
0.53
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
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-
-
Cannot be calculated
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-
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-
-
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-
-
-
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-
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None
Terrestrial ecotoxicology
126
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
-
-
-
-
-
-
-
-
12.0
Columba livia domestica
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.55
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Salmo trutta
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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HUMAN HEALTH AND PROTECTION
High (class III)
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-
126
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
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-
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EU MRL pesticide database 
-
-
-
-
-
-
-
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
No data found
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
?Possibly, status not identified
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
May cause minor lung damage CNS toxicant
Incompatible with lime sulphur
Health: H301 Environment: H400, H410
II (Moderately hazardous)
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-
drazoxolon
drazoxolon
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-
-
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Record last updated:
23/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242