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ethoprophos
** ethoprop ** phosethoprop ** mocap ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for ethoprophos

Description: A broad-spectrum nematicide and insecticide used pre-planting to control nematodes and soil dwelling insects

Example pests controlled: Free-form nematodes; Millipedes; Centipedes; Weevils; Wireworms; Cutworms; Noctuids larvae; Symphylids; Caterpillars; White grubs

Example applications: Ornamentals; Fruit including bananas, pineapples; Tobacco; Potatoes; Vegetables; Sugarcane

Efficacy & activity: Research and testing has shown ethoprophos to offer effective control for soil nematodes and insects when used according to label guidelines.

Availability status: Current

Introduction & key dates: 1966, first reported

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Italy/Ireland
Date inclusion expires 31/07/2019
EU Candidate for substitution (CfS) Yes - low ADI / ARfD / AOEL
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C8H19O2PS2
Canonical SMILES CCCSP(=O)(OCC)SCCC
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) VJYFKVYYMZPMAB-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Nematicide
Substance group Organophosphate
Minimum active substance purity 940 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Non-systemic with contact action. Acetylcholinesterase (AChE) inhibitor.
CAS RN 13194-48-4
EC number 236-152-1
CIPAC number 218
US EPA chemical code 041101
PubChem CID 3289
Molecular mass (g mol-1) 242.3
PIN (Preferred Identification Name) O-ethyl S,S-dipropyl phosphorodithioate
IUPAC name O-ethyl S,S-dipropyl phosphorodithioate
CAS name O-ethyl S,S-dipropyl phosphorodithioate
Other status information Marine Pollutant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance None recorded
Physical state Clear to pale yellow liquid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • Mobil Chemicals
  • Rhone-Poulenc
Example products using this active
  • Mocap 10G
  • Mocap 15G
  • Sanimul
  • Prophos
UK LERAP status None
Formulation and application details Often supplied as granules that are applied directly to the soil or incorporated. It is also available as an emulsifiable concentrate.


ENVIRONMENTAL FATE

for ethoprophos

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 1300 A5 High
Solubility - In organic solvents at 20oC (mg l-1) 500000 A5 - Acetone -
500000 A5 - Methanol -
500000 A5 - Ethyl acetate -
500000 A5 - Toluene -
Melting point (oC) 70 A5 -
Boiling point (oC) 244.3 A5 -
Degradation point (oC) 244.3 A5 -
Flashpoint (oC) 141 A5 -
Octanol-water partition coefficient at pH 7, 20oC P 9.77 X 1002 Calculated -
Log P 2.99 A5 Moderate
Bulk density (g ml-1)/Specific gravity 1.09 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 78.0 A5 Highly volatile
Henry's law constant at 25oC (Pa m3 mol-1) 1.35 X 10-02 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 2.22 Calculated Transition state
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 6.50 X 10-02 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 Neutral soln: 231.0nm=725
Acid soln: 269.0nm=1724
Basic soln: 268.0nm=3815
A5 -
Surface tension (mN m-1) 45.1 A5 at 20oC -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 13.6 A5 Non-persistent
DT50 (lab at 20oC) 13.6 A5 Non-persistent
DT50 (field) 1.3 A5 Non-persistent
DT90 (lab at 20oC) 63.0 A5 -
DT90 (field) 15.1 A5 -
DT50 modelling endpoint 13.6 A5 normalised geometric mean -
Note EU 2017 dossier Lab studies DT50 range 4.8-21.1 days, DT90 range 26.2-89.9 days, Soils = 5; Field study DT50 range 0.61-2.1 days, DT90 range 9.3-20.8 days, Soils =2
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value Stable A5 -
Note Stable
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable pH 5 to pH 7, DT50 83 days at pH 9, 25 degC
Water-sediment DT50 (days) 83 A5 Moderately fast
Water phase only DT50 (days) 20 A5 Slow

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - DW3 Mobile
Koc 70.0
Notes and range -
Freundlich Kf 2.0 A5 Moderately mobile
Kfoc 111
1/n 0.894
Notes and range EU dossier kf range 0.56-5.60, Kfoc range 38-186 mL/g,1/n range 0.82-0.96, Soils=11
pH sensitivity No

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
ethyl phosphate - Plant; Animal - -
O-ethyl-S-propyl-phosphorothioate
Note: Rat LD50 246 mg kg-1 bw
EPPA Plant; Animal - -
O-ethyl-S-methyl-S-propyl-phosphorothioate
Note: Rat LD50 41.0 mg kg-1 bw
SME Plant - -
O-ethyl-O-methyl-S-propyl-phosphorothioate
Note: Rat LD50 19.2 mg kg-1 bw
OME Plant - -
O-ethyl-S-propylphosphorothioic acid AE 0592496 Soil (Aerobic, Anaerobic) - -
N-propyl mercaptan - Rat - -


ECOTOXICOLOGY

for ethoprophos

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 225 Q2 Estimated Threshold for concern
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 40 A4 Rat High
Mammals - Short term dietary NOEL (mg kg-1) 0.1 A5 Rat High
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 6.04 A5 Colinus virginianus High
Birds - Short term dietary (LC50/LD50) 6.51 mg kg bw-1 day-1 A5 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) 0.32 A5 Lepomis macrochirus Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.064 A5 Oncorhynchus mykiss Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.2 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.015 F3 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 28.3 K3 Unknown species Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) 3.2 Q2 Unknown species Low
Honeybees Contact acute 48 hour LD50 (μg bee-1) 5.56 A5 Moderate
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) 39.6 A5 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 8.3 A5 Eisenia foetida, 56 days Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect 100 Mortality
Dose: 7 kg ha-1
A5 Poecilus cupreus, adult
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect 100 Mortality
Dose: 10 kg ha-1
A5 Aleochara bilineata, adult
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 33.3 mg kg-1 soil, 44 days
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for ethoprophos

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 40 A4 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) 7.9 A5 Rabbit -
Mammals - Inhalation LC50 (mg l-1) 0.123 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.0004 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.01 A5 Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.001 A5 Dog, SF=100 -
Dermal penetration studies (%) 10 A5 -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public No unacceptable risks to bystanders identified
Occupational Exposure possible but acceptable under label recommendations for use concerning personal protection clothing and equipment
Dermal exposure likely to be low
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Very toxic by inhalation and dermal absorption
USEPA - probable human carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive
IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H301, H310, H317, H330
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases T+ - Very toxic: R26/27
T - Toxic: R25
Xn - Harmful: R43
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S1/2, S27/28, S36/37/39, S45, S60, S61
WHO Classification Ia - Extremely hazardous
US EPA Classification (formulation) II - Warning - Moderately toxic
UN Number 3018
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group II (medium danger)


TRANSLATIONS

for ethoprophos

Language Name
English ethoprophos
French ethoprophos
German Ethoprophos
Danish ethoprophos
Italian etoprofos
Spanish etoprofos; etoprop
Greek ethoprophos
Slovenian etoprofos
Polish etoprofos
Swedish -
Hungarian -
Dutch ethoprofos

Record last updated: Thursday 23 August 2018
Contact: aeru@herts.ac.uk