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GET ADDITIONAL DATA HERE!

ethoxyquin
** ethoxyquine ** polyethoxyquinoline ** PEQ ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
Further data may be found in the VSDB

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for ethoxyquin

Description: A fungicide used to control scald and other diseases, post-harvest in top fruit normally used in enclosed areas

Example pests controlled: Scald

Example applications: Top fruit

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1990

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Germany
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C14H19NO
Canonical SMILES CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) DECIPOUIJURFOJ-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide, Veterinary substance, Other substance
Other constituent type Antioxidant
Substance group Quinoline
Minimum active substance purity 950 g/kg
Known relevant impurities EU dossier - p-phenetidine 0.75 g/kg
Substance origin Synthetic
Mode of action Anti-oxidant effecting plant growth
CAS RN 91-53-2
EC number 202-075-7
CIPAC number 517
US EPA chemical code 055501
PubChem CID 3293
Molecular mass (g mol-1) 217.34
PIN (Preferred Identification Name) 6-ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline
IUPAC name 1,2-dihydro-2,2,4-trimethylquinolin-6-yl ethyl ether
CAS name 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline
Other status information Chemical subject to PIC regulations; Should not be used on Red Delicious, Golden Delicious or late picked Winesap apples as may reduce quality
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not known
Examples of recorded resistance -
Physical state Yellow to brown coloured viscous liquid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Monsanto
  • Pennwalt
Example products using this active
  • Xedaquine
  • Nix-Scald
  • Stop-Scald
  • Santoquin
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually formulated as an emulsifiable concentrate.


ENVIRONMENTAL FATE

for ethoxyquin

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 60.0 A5 - @ 25 DegC Moderate
Solubility - In organic solvents at 20oC (mg l-1) Miscible A5 - n-Heptane -
Miscible A5 - Methanol -
Miscible A5 - Acetone -
Miscible A5 - Ethyl acetate -
Melting point (oC) < -20 A5 -
Boiling point (oC) 150 A5 -
Degradation point (oC) 150 A5 -
Flashpoint (oC) 150 A5 -
Octanol-water partition coefficient at pH 7, 20oC P 2.45 X 1003 Calculated -
Log P 3.39 A5 High
Bulk density (g ml-1)/Specific gravity 1.03 A5 -
Dissociation constant (pKa) at 25oC 4.56 A5 -
Note: @ 22degC
Vapour pressure at 20oC (mPa) 0.346 A5 - @ 25 degC Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 4.43 X 10-02 A5 - @ 25 degC Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index - - -
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value - - -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - - -
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution: 350nm = 2450, 228nm = 24300; [Acidic solution: 299nm = 1680, 259nm = 6450, 224nm = 24600; [Basic solution: 350nm = 2460, 228nm = 250000 A5 -
Surface tension (mN m-1) 58.5 A5 -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) - - -
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note: -
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - Q2 Slightly mobile
Koc 3208
Notes and range Estimated
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
methylethoxyquin MEQ Plant - -
dihydroethoxyquin DHEQ Plant - -
dihydromethylethoxyquin DHMEQ Plant - -


ECOTOXICOLOGY

for ethoxyquin

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk Q2 Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 1726 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 2417 A5 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) > 1505 mg kg bw-1 day-1 A5 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) 18 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 2 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) 6.1 A5 Pseudokirchneriella subcapitata Low
Honeybees Contact acute 48 hour LD50 (μg bee-1) - - -
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for ethoxyquin

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 1726 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 1.97 A5 Rat, 4 hr (whole body) -
Other Mammal toxicity endpoints Intraperitoneal LD50 = 200 mg kg-1 V3 Mouse -
Intravenous LD50 = 178 mg kg-1 V3 Mouse -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.005 JMPR 2005 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.5 JMPR 2005 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) 100 A3 default -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues May cause dermatitis, probable sensitiser
Possible liver and kidney toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
CLP classification 2013 Health: H302
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R22
EC Safety Classification Click here to view information omn the EU safety phrases S2, S24
WHO Classification NL - Not listed
US EPA Classification (formulation) III - Caution - Slightly toxic
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for ethoxyquin

Language Name
English ethoxyquin
French ethoxyquine
German Ethoxyquin
Danish ethoxyquin
Italian etossichina
Spanish etoxiquina
Greek -
Slovenian etoksikvin
Polish etoksychina
Swedish -
Hungarian etoxiquin
Dutch ethoxychin

Record last updated: Wednesday 23 May 2018
Contact: aeru@herts.ac.uk