(R)-flutriafol |
![]() Last updated: 12/01/2021 |
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(Not known by any other names) |
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A specific isomer of a curative and preventative conazole fungicide used to control leaf and ear diseases usually in cereals | |
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Leaf and ear diseases | |
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Cereals including corn; Soybeans; Apples | |
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Wheat/Mildew=Low; Wheat/Septoria=Low; Wheat/Rust=Low; Soybean/Anthracnose=High; Soybean/Brown spot=High; Soybean/Leaf blight=Moderate; Soybean/Rust=High; Soybean/White mould=Moderate | |
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Current | |
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1981 |
UK regulatory status |
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Approved (as racemate) | ||
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31/05/2024 | ||
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None |
EC Regulation 1107/2009 (repealing 91/414) |
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Approved (as racemate) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Slovakia/UK | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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31/05/2021 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes (as racemate) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Australia, Brazil, South Africa, Russia, Tanzania |
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Chemical structure |
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(R)-flutriafol is the R-isomer of chiral flutriafol | |
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C₁₆H₁₃F₂N₃O | |
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C1=CC=C(C(=C1)C(CN2C=NC=N2)(C3=CC=C(C=C3)F)O)F | |
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C1=CC=C(C(=C1)[C@@](CN2C=NC=N2)(C3=CC=C(C=C3)F)O)F | |
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InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2/t16-/m1/s1 | |
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JWUCHKBSVLQQCO-MRXNPFEDSA-N | |
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Yes |
General status |
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Fungicide | |
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Triazole | |
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920 g kg⁻¹ | |
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EU dossier - dimethyl sulphate: <0.01%; dimethylformamide:<0.1%; methanol: <0.1% | |
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Synthetic | |
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Broad-spectrum, systemic, contact action with eradicant and protective properties. Sterol biosynthesis inhibitor. | |
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76674-21-0 | |
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436 | |
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128940 | |
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13309131 | |
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301.29 | |
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(R)-2,4'-difluoro-α-(1H-1,2,4-triazol-1-ylmethyl)benzhydryl alcohol | |
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α-(2-fluorophenyl)-α-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol | |
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A marine pollutant | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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3 | |
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White crystalline solid | |
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Formulations |
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Often supplied as a soluble concentrate that is mixed with water and applied as a spray |
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7.2 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature data range 5.2-9.2 days, 2 crops, grown undercover, fruit matrix, n=2 | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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> 1140 | B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Rat as isomer mix4 = Verified data |
Moderate | ||||||||
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616 | A3 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Alectoris rufa as isomer mix3 = Unverified data of known source |
Moderate | ||||||||
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33.0 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Lepomis macrochirus as isomer mix4 = Verified data |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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> 1140 | B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Rat as isomer mix4 = Verified data |
Moderate | ||||||||
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1000 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat as isomer mix4 = Verified data |
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- | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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0.01 | B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) UK ACP 19994 = Verified data |
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0.05 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Dog SF=1005 = Verified data used for regulatory purposes |
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0.05 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Dog SF=1005 = Verified data used for regulatory purposes |
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0.3-10.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) concentration dependent5 = Verified data used for regulatory purposes |
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Acceptable risk for proposed uses | |||||||||
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Acceptable risk for proposed uses | ||||||||||
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Health issues |
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Possible liver toxicant May cause anaemia Endocrine issues - Weak estrogen inhibition |
Handling issues |
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Prevent generation of mists Not explosive or oxidising IMDG Transport Code 9 |
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Health: H340, H360fd Environment: H400, H410 |
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Reproduction risk category 3: R63 Xn - Harmful: R20/21/22 N - Dangerous for the environment: R52, R53 |
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S22, S24, S25 | |||
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II (Moderately hazardous) | |||
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3077 | |||
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Packaging Group III (minor danger) |
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(R)-flutriafol | ||
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(R)-flutriafol | ||
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(R-)Flutriafol | ||
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(R)-flutriafol | ||
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(R)-flutriafol | ||
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(R)-flutriafol | ||
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(R)-flutriafol | ||
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(R)-flutriafol | ||
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Record last updated: | 12/01/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |