Mefenpyr diethyl (Ref: HOE 107892)
Last updated: 16/11/2022
(Also known as: mefenpyr-diethyl; AE F107892; AEF 107892)
Mefenpyr diethyl is a herbicide safener with no herbicidal activity. It has a low aqueous solubility, is relatively volatile and a low potential for groundwater leaching. It is non-persistent in soil and moderately persistent in aquatic systems. it is not highly toxic to mammals and no serious human health issues have been reported although it is an irritant. It is moderately toxic to birds, earthworms and most aquatic organisms. It is not toxic to honeybees.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A herbicide safener used with fenoxaprop-P-ethyl and iodosulfuron for selective weed control in cereals
Current
-
Not approved
Not applicable
Not applicable
EC Regulation 1107/2009 (repealing 91/414)
Not applicable - not a ppp. May be authorised at national level under different legislation
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
A chiral molecule. The technical material is an isomeric mixture.
C₁₆H₁₈Cl₂N₂O₄
CCOC(=O)C1=NN(C(C1)(C)C(=O)OCC)C2=C(C=C(C=C2)Cl)Cl
No data
OPGCOAPTHCZZIW-UHFFFAOYSA-N
InChI=1S/C16H18Cl2N2O4/c1-4-23-14(21)12-9-16(3,15(22)24-5-2)20(19-12)13-7-6-10(17)8-11(13)18/h6-8H,4-5,9H2,1-3H3
Yes
Other substance
Herbicide safener
Unclassified substance
>940 g kg⁻¹
FAO: may potentially contain ethyl-2-chloro-2-(2,4-dichloro-phenylhydrazono)acetate as an inpurity
Synthetic
Enhances the metabolism of mesosulfuron-methyl and iodosulfuron-methyl
135590-91-9
603-923-2
651.229
-
-
373.23
rac-diethyl (5R)-1-(2,4-dichlorophenyl)-5-methyl-4,5-dihydro-1H-pyrazole-3,5-dicarboxylate
diethyl (RS)-1-(2,4-dichlorophenyl)-4,5-dihydro-5-methyl-1H-pyrazole-3,5-dicarboxylate
diethyl 1-(2,4-dichlorophenyl)-4,5-dihydro-5-methyl-1H-pyrazole-3,5-dicarboxylate
-
-
Not applicable
Not applicable
Not applicable
Not applicable
-
White to beige crystals
Aventis Bayer Crop Science
Available in a variety of formulations including oil in water emulsions, soluble concentrates and water dispersible granules.
20
Low
500000
Acetone
-
400000
Toluene
-
400000
Methanol
-
400000
Ethyl acetate
-
51
-
-
-
-
260
-
-
-
-
6.76 X 1003
Calculated
-
3.83
High
-
-
-
-
-
-
1.31
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
6.30 X 10-03
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
2.55 X 10-04
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
-
-
-
-
-
-
-
17.5
Non-persistent
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Best available data
-
-
-
-
-
-
-
-
198
Stable
-
41
Moderately persistent
-
135
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
Slow
80
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
Stable
Soil adsorption and mobility
-
Slightly mobile
634
Best available data
-
-
-
-
-
-
-
1.49
Calculated
Low leachability
3.23 X 10-02
Calculated
-
-
Low
Calculated
-
Slightly mobile
Calculated
-
-
-
-
-
-
None
Terrestrial ecotoxicology
> 5000
Rat
Low
48
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Rat 2 year
High
-
-
-
-
-
> 2000
Coturnix japonica
Low
-
-
-
-
-
-
> 1000
Eisenia foetida
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 700
Apis mellifera
Low
> 926
Apis mellifera
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4.2
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
53
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
12
Lemna gibba 7 day
Low
1.65
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Navicula pelliculosa
Moderate
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 5000
Rat
Low
4000
Rat
-
> 1.32
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
0.1
UK ACP 1997
-
-
-
-
-
-
-
0.3
UK ACP 1997
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B3 B = DNA damage/repair (EFSA database) 3 = Negative
; C3 C = Gene mutation (EFSA database) 3 = Negative
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
XNo, known not to cause a problem
XNo, known not to cause a problem
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
XNo, known not to cause a problem
 
No further information available
No information available
-
NL (Not listed)
3077
Packging group III (minor danager)
mefenpyr diethyl
-
-
-
mefenpir-dietile
-
-
-
-
-
-
Record last updated:
16/11/2022
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242