Flocoumafen (Ref: BAS 322l) |
![]() Last updated: 23/01/2021 |
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(Also known as: WL 108366; CL 183540) |
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A rodenticide especially useful against rodents that have become resistant to other anticoagulants | |
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Rats, Mice | |
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Current | |
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circa 1985 |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Poland | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Australia |
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Chemical structure |
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A molecule with two chiral centres existing in the cis- and trans-forms. Flocoumafen is mainly comprised of a mixture of the CIS isomers. | |
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C₃₃H₂₅F₃O₄ | |
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C1C(CC2=CC=CC=C2C1C3=C(C4=CC=CC=C4OC3=O)O)C5=CC=C(C=C5)OCC6=CC=C(C=C6)C(F)(F)F | |
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No data | |
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KKBGNYHHEIAGOH-UHFFFAOYSA-N | |
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InChI=1S/C33H25F3O4/c34-33(35,36)24-13-9-20(10-14-24)19-39-25-15-11-21(12-16-25)23-17-22-5-1-2-6-26(22)28(18-23)30-31(37)27-7-3-4-8-29(27)40-32(30)38/h1-16,23,28,37H,17-19H2 | |
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Yes |
General status |
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Rodenticide | |
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Coumarin anticoagulant | |
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Synthetic | |
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Second generation indirect anticoagulant | |
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90035-08-8 | |
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421-960-0 | |
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453 | |
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54698175 | |
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542.54 | |
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4-hydroxy-3-[(1?,3?)-3-(4-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-2H-1-benzopyran-2-one (mixture of cis- to trans-isomers in the ratio range 60:40 to 40:60 respectively) | |
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4-hydroxy-3-[(1RS,3RS;1RS,3SR)-1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin | |
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4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]-1-naphthalenyl]-2H-1-benzopyran-2-one | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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Off-white solid | |
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Formulations |
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Usually supplied as ready-to-use cereal-based block baits and pelleted baits containing 0.005% flocoumafen |
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1.04 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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600000 | C4 C = AGRITOX (click here ) Acetone4 = Verified data |
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34000 | C4 C = AGRITOX (click here ) Ethanol4 = Verified data |
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44000 | C4 C = AGRITOX (click here ) Octanol4 = Verified data |
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33000 | C4 C = AGRITOX (click here ) Xylene4 = Verified data |
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92.5 | B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 4 = Verified data |
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5.01 X 1004 | Calculated | - | |||||||
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4.7 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
High | ||||||||
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1.23 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
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2.67 X 10-04 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Low volatility | ||||||||
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7.43 X 10-08 | Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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217 | C4 C = AGRITOX (click here ) 4 = Verified data |
Persistent | |||||||
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217 | C4 C = AGRITOX (click here ) 4 = Verified data |
Persistent | ||||||||
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447 | C4 C = AGRITOX (click here ) 4 = Verified data |
Very persistent | |||||||
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Stable pH 7 to pH 9 up to 50 °C | ||||||||||
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Soil adsorption and mobility |
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- | Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source |
Slightly mobile | |||||||
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1345 | ||||||||||
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Estimated | ||||||||||
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Fate indices |
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2.04 | Calculated | Transition state | ||||||||||||||||||||||||||
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8.78 X 10-02 | Calculated | - | |||||||||||||||||||||||||
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High | Calculated | - | ||||||||||||||||||||||||||
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Slightly mobile | Calculated | - |
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1972 | Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source |
Threshold for concern | |||||||
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Not available | - | |||||||||
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0.25 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
High | ||||||||
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> 300 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Coturnix japonica5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.091 | F5 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
High | ||||||||
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0.66 | F5 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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1.1 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Raphidocelis subcapitata4 = Verified data |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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0.25 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
High | ||||||||
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0.87 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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0.0008 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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List II | - | - | ||||||||
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Public and consumer exposure should be low or non-existent since flocoumafen is no longer used in most countries | |||||||||
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May be absorbed through the skin Occupational exposure should be low or non-existent since flocoumafen is no longer used in most countries |
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Health issues |
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Highly toxic May cause massive hemorrhage resulting in shock |
Handling issues |
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No information available | |||
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Health: H300, H310, H330, H372 Environment: H400, H410 |
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T+ - Very toxic: R26/27/28 T - Toxic: R48/23/24/25 N - Dangerous for the environment: R50, R53 |
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S1/2, S28, S36/37/39, S45, S60, S61 | |||
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Ia (Extremely hazardous) | |||
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3027 | |||
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flocoumafen | ||
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flocoumafen | ||
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Flocoumafen | ||
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flocoumafen | ||
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flocumafen | ||
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flocumafen | ||
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flokumafen | ||
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flokumafen | ||
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flokumafen | ||
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Record last updated: | 23/01/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |