Fomesafen (Ref: PP 021) |
![]() Last updated: 27/11/2019 |
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(Also known as: fomesafene; fomesafen acid) |
SUMMARY |
Fomesafen is a selective herbicide that does not have approval for use in the EU. It is moderately soluble in aqueous solution, is relatively volatile but does have potential to leach to groundwater. It is persistent in soils and aquatic systems. It is moderately toxic to mammals and although a recognised irritant no other significant health issues have been identified. It is not toxic to birds or fish but considered moderately toxic to aquatic crustaceans, honeybees and earthworms. |
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A pre-emergence herbicide for use in leguminous crops for post-emergence control of broad-leaved weeds | |
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Pigweed, Black nightshade, Velvetleaf, Cocklebur | |
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Legumes; Cotton; Soybeans; Potatoes; Tomatoes | |
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Unknown | |
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1983, first reported |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Chemical structure |
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C₁₅H₁₀ClF₃N₂O₆S | |
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CS(=O)(=O)NC(=O)C1=C(C=CC(=C1)OC2=C(C=C(C=C2)C(F)(F)F)Cl)[N+](=O)[O-] | |
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No data | |
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BGZZWXTVIYUUEY-UHFFFAOYSA-N | |
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InChI=1S/C15H10ClF3N2O6S/c1-28(25,26)20-14(22)10-7-9(3-4-12(10)21(23)24)27-13-5-2-8(6-11(13)16)15(17,18)19/h2-7H,1H3,(H,20,22) | |
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Yes |
General status |
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Herbicide | |
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Organochlorine | |
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Synthetic | |
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Selective, absorbed by leaves and roots. Inhibits protoporphyrinogen oxidase (PROTOX), leading to irreversible cell membrane damage. | |
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72178-02-0 | |
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276-439-9 | |
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8162 | |
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123802 | |
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51556 | |
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438.76 | |
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- | |
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5-(2-chloro-α,α,α-trifluoro-p-tolyloxy)-N-mesyl-2-nitrobenzamide | |
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5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitrobenzamide | |
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- | |
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- | |
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E | |
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14 | |
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Not applicable | |
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Not applicable | |
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Amaranthus rudis, Euphorbia heterophylla | |
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White crystals | |
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Formulations |
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Usually supplied as an soluble concentrate or liquid concentratate. |
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50 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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300000 | C4 C = AGRITOX (click here ) Acetone4 = Verified data |
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25000 | C4 C = AGRITOX (click here ) Methanol4 = Verified data |
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1900 | C4 C = AGRITOX (click here ) Xylene4 = Verified data |
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10000 | C4 C = AGRITOX (click here ) Dichloromethane4 = Verified data |
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219 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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6.31 X 10-02 | Calculated | - | |||||||
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-1.2 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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1.61 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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2.83 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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Forms water soluble salts, strong acid | |||||||||||
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4.00 X 10-03 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Low volatility | ||||||||
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2.00 X 10-07 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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86 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Moderately persistent | |||||||
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86 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Moderately persistent | ||||||||
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Field studies DT₅₀ range 59-112 days | ||||||||||
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Stable | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Stable | |||||||
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7 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Fast | ||||||||
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Soil adsorption and mobility |
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- | B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 4 = Verified data |
Mobile | |||||||
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50 | ||||||||||
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Literature studies state Koc range 150-1200 (R3) | ||||||||||
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1.89 | R4 R = Peer reviewed scientific publications 4 = Verified data |
Moderately mobile | |||||||
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228 | ||||||||||
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0.77 | ||||||||||
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Literature data: Kf range 1.38-3.02 mL g⁻¹, Kfoc range 115-348 mL g⁻¹, 1/n range 0.65-0.83, soils=6 | ||||||||||
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R4 |
Fate indices |
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3.18 | Calculated | High leachability | ||||||||||||||||||||||||||
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4.08 X 10-01 | Calculated | - | |||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Mobile | Calculated | - |
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6 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Whole fish4 = Verified data |
Low potential | |||||||
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Not available | - | |||||||||
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1250 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Rat5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.25 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Rat5 = Verified data used for regulatory purposes |
High | |||||||
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> 5000 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Anas platyrhynchos5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 170 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 330 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Daphnia magna5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 100 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna LOEC3 = Unverified data of known source |
Low | ||||||||
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22.1 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Americamysis bahia3 = Unverified data of known source |
Moderate | ||||||||
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0.17 | L2 L = Pesticide manuals and hard copy reference books / other sources Unknown species2 = Unverified data of unknown source |
Moderate | ||||||||
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50 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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1000 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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1250 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Rat5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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1000 | L3 L = Pesticide manuals and hard copy reference books / other sources Rabbit3 = Unverified data of known source |
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> 4.97 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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0.003 | B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) UK ACP 19994 = Verified data |
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List I | - | - | ||||||||
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Occupational exposure may occur through inhalation of spray mists and aerosols and dermal contact | ||||||||||
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Health issues |
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Probably liver toxicant |
Handling issues |
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No information available | |||
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Health: H302 | |||
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Xn - Harmful: R22 | |||
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S2 | |||
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II (Moderately hazardous) | |||
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fomesafen | ||
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fomesafen | ||
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Fomesafen | ||
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fomesafen | ||
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fomosafen | ||
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fomesafen | ||
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fomesafen | ||
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fomezafen | ||
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Record last updated: | 27/11/2019 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |