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formothion (Ref: SAN 6913I)
** ENT 27257 ** OMS 968 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for formothion

Description: An obsolete insecticide and acaricide once used to control spider mites, aphids, psyllids, mealy bugs, whiteflies and many other insect pests

Introduction: circa 1962

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur -
Date inclusion expires Expired

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Insecticide, Acaricide
Substance group Organothiophosphate
Substance origin Synthetic
Mode of action Systemic with contact action. Acetylcholinesterase (AChE) inhibitor.
CAS RN 2540-82-1
EC number 219-818-6
CIPAC number 160
US EPA chemical code 366400
Chiral molecule No
Chemical formula C6H12NO4PS2
SMILES O=C(N(C=O)C)CSP(=S)(OC)OC
International Chemical Identifier (InChI) InChI=1/C6H12NO4PS2/c1-7(5-8)6(9)4-14-12(13,10-2)11-3/h5H,4H2,1-3H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 257.27
PIN (Preferred Identification Name) -
IUPAC name 2-dimethoxyphosphinothioylthio-N-formyl-N-methylacetamide
CAS name S-[2-(formylmethylamino)-2-oxoethyl] O,O-dimethyl phosphorodithioate
Other status information -
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Physical state Yellow viscous liquidy crystals
Related substances & organisms -

Formulations:
Property Value
Example manufacturers of products using this active -
Example products using this active
  • Sandothion
  • Anthiomix
UK LERAP status No UK approval for use or outside scope
Formulation and application details -


ENVIRONMENTAL FATE

for formothion

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 2600 K4 High
Solubility - In organic solvents at 20oC (mg l-1) - - -
Melting point (oC) 25 Q3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 3.02 X 1001 Calculated -
Log P 1.48 G4 Low
Bulk density (g ml-1)/Specific gravity 1.37 Q2 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 0.11 K4 Non-volatile
Henry's law constant at 25oC (Pa m3 mol-1) 1.11 X 10-05 V3 Non-volatile
Henry's law constant at 20oC (dimensionless) 4.60 X 10-09 K3 Non-volatile
GUS leaching potential index 3.07 Calculated High leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 1.64 X 10-01 Calculated -
Note -
Potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 14 G4 Non-persistent
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Best available data
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 0.17 K3 Non-persistent
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - P3 Mobile
Koc 21
Notes and range Best available data
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 91/414 relevancy
dimethoate (Ref: OMS 94) Soil   0.700   Major fraction, Relevant


ECOTOXICOLOGY

for formothion

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF 0.07 Q2 Estimated Low potential
CT50 (days) Not available -
Bioaccumulation potential - Calculated Low
Mammals - Acute oral LD50 (mg kg-1) 365 G4 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 630 G3 Columbidae Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 38.3 K3 Unknown species Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 16.1 W3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) 42.3 W2 Unknown species Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (μg bee-1) 0.15 K4 Contact High
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for formothion

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) 365 G4 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) - - -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
Examples of European MRLs (mg kg-1) Value -
Note For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

General human health issues May cause blurred vision, muscle spasms or loss of coordination

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General No information available
CLP classification 2013 -
EC Risk Classification Xn - Harmful: R21/22
EC Safety Classification S2, S36/37
WHO Classification O - Obsolete substance
US EPA Classification (formulation) - - -
UN Number -
Waste disposal & packaging -


TRANSLATIONS

for formothion

Language Name
English formothion
French formothion
German Formothion
Danish formothion
Italian formothion
Spanish formotion
Greek formothion
Slovenian formotion
Polish formotion
Swedish -
Hungarian -
Dutch formothion

Record last updated: Monday 08 August 2011
Contact: aeru@herts.ac.uk