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formothion (Ref: SAN 6913I)
** ENT 27257 ** OMS 968 ** J-38 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for formothion

Description: An obsolete systemic, broad spectrum insecticide and acaricide

Example pests controlled: Spider mites; Aphids; Psyllids; Mealy bugs; Whiteflies

Example applications: Tree fruit; Vines; Olives; Hops; Cereals; Sugarcane; Rice

Availability status: Obsolete

Introduction & key dates: 1961, first reported

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur -
Date inclusion expires Expired

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Insecticide, Acaricide
Substance group Organophosphate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Systemic with contact action. Cholinesterase inhibitor.
CAS RN 2540-82-1
EC number 219-818-6
CIPAC number 160
US EPA chemical code 366400
Chiral molecule No
Chemical formula C6H12NO4PS2
SMILES O=C(N(C=O)C)CSP(=S)(OC)OC
International Chemical Identifier key (InChIKey) AIKKULXCBHRFOS-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C6H12NO4PS2/c1-7(5-8)6(9)4-14-12(13,10-2)11-3/h5H,4H2,1-3H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 257.27
PIN (Preferred Identification Name) -
IUPAC name 2-dimethoxyphosphinothioylthio-N-formyl-N-methylacetamide
CAS name S-[2-(formylmethylamino)-2-oxoethyl] O,O-dimethyl phosphorodithioate
Other status information Phytotoxic to some varieties of peach, apricot and cherry
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Bactrocera dorsalis
Myzus persicae
Rhizoglyphus robini
Tetranychus urticae
Bemisia tabaci
Boophilus microplus
many others
Physical state Yellow viscous liquidy crystals
Related substances & organisms -

Formulations:
Property Value
Example manufacturers & suppliers of products using this active now or historically
  • Sandoz AG
  • Novartis
Example products using this active
  • Sandothion
  • Anthiomix
  • Aflix
  • Anthio
UK LERAP status No UK approval for use or outside scope
Formulation and application details Usually formulated as an emulsifiable concentrate or ULV.


ENVIRONMENTAL FATE

for formothion

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 2600 K4 High
Solubility - In organic solvents at 20oC (mg l-1) Miscible L3 - Benzene -
Miscible L3 - Xylene -
Miscible L3 - Toluene -
Miscible L3 - Chloroform -
Melting point (oC) 25 L3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 3.02 X 1001 Calculated -
Log P 1.48 G4 Low
Bulk density (g ml-1)/Specific gravity 1.36 L3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 0.113 K4 Volatile
Henry's law constant at 25oC (Pa m3 mol-1) 1.11 X 10-05 V3 Non-volatile
Henry's law constant at 20oC (dimensionless) 4.60 X 10-09 K3 Non-volatile
GUS leaching potential index 3.07 Calculated High leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 1.64 X 10-01 Calculated -
Note -
Potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 14 G4 Non-persistent
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Literature states that DT50 is between 0.5 - 15 days. Loamy soil <1 day.
Foliar DT50 (days) Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 0.17 K3 Non-persistent
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - P3 Mobile
Koc 21
Notes and range Best available data
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 91/414 relevancy
dimethoate (Ref: OMS 94) Soil   0.700   Major fraction, Relevant


ECOTOXICOLOGY

for formothion

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF (l kg-1) 0.07 Q2 Estimated Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 365 G4 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 630 G3 Columbidae Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 38.3 L3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 16.1 W3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 42.3 L3 Scenedesmus subspicatus Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) 0.15 K4 High
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) 157.7 L3 Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for formothion

General:
Property Value Source/Quality Score/Other Information Interpretation
Threshold of Toxicological Concern (Cramer Class) High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 365 G4 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) - - -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues May cause blurred vision, muscle spasms or loss of coordination

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General Incompatible with alkaline substances
CLP classification 2013 Health: H302, H312
EC Risk Classification Xn - Harmful: R21/22
EC Safety Classification S2, S36/37
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) - -
UN Number -
Waste disposal & packaging -


TRANSLATIONS

for formothion

Language Name
English formothion
French formothion
German Formothion
Danish formothion
Italian formothion
Spanish formotion
Greek formothion
Slovenian formotion
Polish formotion
Swedish -
Hungarian -
Dutch formothion

Record last updated: Saturday 19 March 2016
Contact: aeru@herts.ac.uk