Halofenozide (Ref: RH 0345) |
![]() Last updated: 18/12/2020 |
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(Also known as: halofenoxide; CL 290816) |
SUMMARY |
Halofenozide is a soil insecticide without EU regulatory approval for use. It has a low aqueous solubility and, based on its chemical properties, it may have a tendency to leach to groundwater. It can be persistent in soil systems and, under certain conditions, may also persist in aquatic systems. Whilst it has a relatively low mammalian toxicity there is some concern regarding its potential to bioaccumulate. It is moderately toxic to many aquatic species, honey bees and earthworms but is only slightly toxic to birds. |
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A insecticide for the larval stage control of insects on grass | |
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White grub larvae including those from Japanese beetles, Northern and Northern masked chafers, Oriental beetles, Lepidoptera karvae including cutworms, sod wetworms and armyworms | |
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Lawns; Golf courses; Turf | |
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Obsolete | |
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1997 |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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USA |
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Chemical structure |
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C₁₈H₁₉ClN₂O₂ | |
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CC(C)(C)N(C(=O)C1=CC=CC=C1)NC(=O)C2=CC=C(C=C2)Cl | |
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No data | |
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CNKHSLKYRMDDNQ-UHFFFAOYSA-N | |
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InChI=1S/C18H19ClN2O2/c1-18(2,3)21(17(23)14-7-5-4-6-8-14)20-16(22)13-9-11-15(19)12-10-13/h4-12H,1-3H3,(H,20,22) | |
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Yes |
General status |
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Insecticide, Insect growth regulator | |
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Unclassified | |
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Synthetic | |
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Systemic with stomach action. Disrupts the hormonal systems that control insect growth and moulting. Ecdysone agonist /disruptor. | |
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112226-61-6 | |
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431-600-4 | |
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None allocated | |
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- | |
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114994 | |
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330.81 | |
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- | |
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N-tert-butyl-N'-(4-chlorobenzoyl)benzohydrazide | |
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4-chlorobenzoic acid 2-benzoyl-2-(1,1-dimethylethyl)hydrazide | |
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Not applicable | |
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Not applicable | |
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18A | |
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Not applicable | |
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None identified | |
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White crystalline solid with mild amino odour |
Formulations |
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12.3 | J4 J = Pesticide Action Network database (click here ) 4 = Verified data |
Low | ||||||||
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31000 | L3 L = Pesticide manuals and hard copy reference books / other sources Isopropanol3 = Unverified data of known source |
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154000 | L3 L = Pesticide manuals and hard copy reference books / other sources Cyclohexanone3 = Unverified data of known source |
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200 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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2.19 X 1003 | Calculated | - | |||||||
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3.34 | K3 K = Research datasets, e.g. Pandora, Demetra 3 = Unverified data of known source |
High | ||||||||
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0.46 | F2 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 2 = Unverified data of unknown source |
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Degradation |
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219 | J4 J = Pesticide Action Network database (click here ) 4 = Verified data |
Persistent | |||||||
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220 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Persistent | ||||||||
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DT₅₀ 219 days aerobic, 60.0 days anaerobic; Other sources: 129 days (DW4); 68 (silt loam) to 818 (sand loam) (F4) | ||||||||||
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52 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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Published literature RL₅₀ range 5.0-100 days, grass, n=2 | ||||||||||
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10 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderately fast | |||||||
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Value for pond water | ||||||||||
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Stable | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Stable | |||||||
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pH variable: DT₅₀ 310 days at pH 5, 481 days at pH 7, 226 days at pH 9 | ||||||||||
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Soil adsorption and mobility |
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- | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 4 = Verified data |
Moderately mobile | |||||||
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250 | ||||||||||
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EU dossier 1031 mL g⁻¹ (US3, DW3), 224-279 mL g⁻¹ (L3); 149-360 mL g⁻¹ (F4) | ||||||||||
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Fate indices |
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3.75 | Calculated | High leachability | ||||||||||||||||||||||||||
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9.48 X 10-01 | Calculated | - | |||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Moderately mobile | Calculated | - |
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100 | E3 E = Manufacturers safety data sheets Worst case data3 = Unverified data of known source |
Threshold for concern | |||||||
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2850 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat3 = Unverified data of known source |
Low | ||||||||
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> 2250 | F5 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Colinus virginianus5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 8.6 | F5 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 0.029 | P3 P = Other governments and regulators Gambusia affinis 15 day3 = Unverified data of known source |
Moderate | ||||||||
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> 3.2 | F5 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 0.2 | P4 P = Other governments and regulators Daphnia magna4 = Verified data |
Moderate | ||||||||
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> 2.9 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Americamysis bahia3 = Unverified data of known source |
Moderate | ||||||||
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> 0.63 | F5 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Pseudokirchneriella subcapitata5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 100 | F5 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 5 = Verified data used for regulatory purposes |
Low | |||||||
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> 980 | E3 E = Manufacturers safety data sheets Eisenia foetida3 = Unverified data of known source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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2850 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat3 = Unverified data of known source |
Low | ||||||||
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2000 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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2.7 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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Health issues |
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May cause methemoglobinemia Possible blood, liver and CNS toxicant |
Handling issues |
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No information available | |||
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Health: H317 Environment: H411 |
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Not classified: Obsolete | |||
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Not classified: Obsolete | |||
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III (Slightly hazardous) | |||
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halofenozide | ||
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halofenozide | ||
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Halofenozid | ||
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halofenozid | ||
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halofenozide | ||
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halofenozide | ||
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halofenozyd | ||
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Record last updated: | 18/12/2020 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |