Heptachlor (Ref: ENT 15152) |
![]() Last updated: 09/02/2021 |
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(Also known as: heptachlore; E3314; H-34; OMS 193) |
SUMMARY |
Heptachlor in an insecticide that is not approved for use in the EU. It has a low aqueous solubility but is highly soluble in most organic solvents. It is volatile and has low potential for leaching to groundwater. heptachlor can be persistent in soil systems but is not generally persistent in water systems. It is moderately toxic to mammals and may bioaccumulate. heptachlor may also cause adverse reproduction/development effects and is a neurotoxin. It is moderately toxic to birds but highly toxic to honeybees and most aquatic species. |
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An obsolete insecticide once used to kill termites, ants and other insects in agricultural and domestic situations | |
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Ants; Termites; Cutworms; Maggots; Spittlebugs; Weevils; Wireworms; Japanese beetles; Mosquitoes | |
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Corn; Sorghum; Small grains | |
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- | |
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Obsolete, Banned | |
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1951, first reported |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Costa Rica |
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Chemical structure |
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A molecule with 5 chiral centres | |
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C₁₀H₅Cl₇ | |
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C1=CC(C2C1C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl)Cl | |
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No data | |
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FRCCEHPWNOQAEU-UHFFFAOYSA-N | |
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InChI=1S/C10H5Cl7/c11-4-2-1-3-5(4)9(15)7(13)6(12)8(3,14)10(9,16)17/h1-5H | |
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Yes |
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Common Name | Relationship | Link |
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heptachlor epoxide | Metabolite | ![]() |
heptachlor | - | ![]() |
General status |
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Insecticide | |
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Organochlorine | |
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Synthetic | |
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Persistent, non-systemic contact and stomach poison with some fumigant action. Is a chloride channel-blocking agent. | |
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76-44-8 | |
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200-962-3 | |
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36 | |
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044801 | |
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3589 | |
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373.32 | |
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- | |
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1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene | |
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1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene | |
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Chemical subject to PIC regulations; POP - regulated by Stockholm Convention; LRTAP Annex 1; OSPAR soc; Severe Marine Pollutant; Rotterdam Convention (Class O) | |
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- | |
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Not applicable | |
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Not applicable | |
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2A | |
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Not applicable | |
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Anthonomus grandis, Delia brassicae, Diabrotica longicornis, Psilia rosae, Conoderus falli, Diabrotica virgifera, many others | |
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White to tan coloured crystals |
Formulations |
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Available in a wide variety of formulations including wettable powders, emulsifiable concentrates, dusts and oil solutions |
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0.056 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
Low | ||||||||
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750000 | L3 L = Pesticide manuals and hard copy reference books / other sources Acetone3 = Unverified data of known source |
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1060000 | L3 L = Pesticide manuals and hard copy reference books / other sources Benzene3 = Unverified data of known source |
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1020000 | L3 L = Pesticide manuals and hard copy reference books / other sources Xylene3 = Unverified data of known source |
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45000 | L3 L = Pesticide manuals and hard copy reference books / other sources Ethanol3 = Unverified data of known source |
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95 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) 3 = Unverified data of known source |
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135 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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2.75 X 1005 | Calculated | - | |||||||
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5.44 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
High | ||||||||
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1.58 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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53 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
Highly volatile | ||||||||
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3.53 X 1002 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Volatile | ||||||||
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Degradation |
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- | ||||||||||
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285 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Persistent | |||||||
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- | - | - | ||||||||
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250 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Persistent | ||||||||
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Other sources: DT₅₀ around 2 yrs (R3), 9-10 months (R3) | ||||||||||
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4.8 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 1.0-13.5 days, 4 field crops, various matrices, n=5 | ||||||||||
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1 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
Non-persistent | |||||||
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Soil adsorption and mobility |
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- | G3 G = Extension Toxicology network database EXTOXNET (click here ) 3 = Unverified data of known source |
Non-mobile | |||||||
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24000 | ||||||||||
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Other sources: 21878 mL g⁻¹ (R3) | ||||||||||
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Fate indices |
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-0.91 | Calculated | Low leachability | ||||||||||||||||||||||||||
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5.35 X 10-03 | Calculated | - | |||||||||||||||||||||||||
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Estimated concentrations of chemicals with Koc values greater than 9995 ml g⁻¹ are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW | ||||||||||||||||||||||||||||
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High | Calculated | - | ||||||||||||||||||||||||||
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Non-mobile | Calculated | - |
Key metabolites |
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Soil | - | Not assessed under 91/414 or 1107/2009 |
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2430 | R3 R = Peer reviewed scientific publications (whole body)3 = Unverified data of known source |
Threshold for concern | |||||||
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Not available | - | |||||||||
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> 147 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
Moderate | ||||||||
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- | L1 L = Pesticide manuals and hard copy reference books / other sources Rat1 = Estimated data with little or no verification |
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5 | - | |||||||||
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> 2000 | L3 L = Pesticide manuals and hard copy reference books / other sources Anas platyrhynchos3 = Unverified data of known source |
Low | ||||||||
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0.007 | L3 L = Pesticide manuals and hard copy reference books / other sources Oncorhynchus mykiss3 = Unverified data of known source |
High | ||||||||
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0.042 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna4 = Verified data |
High | ||||||||
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0.027 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Pseudokirchneriella subcapitata4 = Verified data |
Moderate | ||||||||
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> 0.526 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
High | |||||||
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0.0168 | R4 R = Peer reviewed scientific publications Trigona spinipes4 = Verified data |
High | |||||||
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Contact | ||||||||||
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General |
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High (class III) | - | - | ||||||||
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> 147 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
Moderate | ||||||||
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195 | R3 R = Peer reviewed scientific publications Rat3 = Unverified data of known source |
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2.0 | R3 R = Peer reviewed scientific publications Rat3 = Unverified data of known source |
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0.0001 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) JMPR3 = Unverified data of known source |
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List I; List II | - | - | ||||||||
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Risk of exposure via food is now considered negligible | |||||||||
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May be absorbed through intact skin | ||||||||||
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UK statutory standard for protection of drinking water: 0.030 µg l⁻¹; EU Directive 2008/105/EC standard for protection of drinking water: 0.030 µg l⁻¹ | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) UK EA QS database 20185 = Verified data used for regulatory purposes |
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0.03 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) UK EA QS database 20185 = Verified data used for regulatory purposes |
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Health issues |
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Bioaccumulates Liver toxicant Endocrine issues - Binding to cellular estrogen and androgen receptors |
Handling issues |
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Incompatible with alkaline substances | |||
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Health: H301, H311, H351, H373 Environment: H400, H410 |
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Carcinogen category 3: R40 T - Toxic: R24/25, R33 N - Dangerous for the environment: R50, R53 |
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S1/2, S36/37, S45, S60, S61 | |||
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II (Moderately hazardous) | |||
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heptachlor | ||
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heptachlore | ||
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Heptachlor | ||
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heptachlor | ||
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eptaclor | ||
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heptaclor | ||
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heptachlor | ||
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heptachlor | ||
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heptachloor |
Record last updated: | 09/02/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |