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heptachlor (Ref: ENT 15152)
** heptachlore ** E3314 ** H-34 ** OMS 193 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for heptachlor

Description: An obsolete insecticide once used to kill termites, ants and other insects in agricultural and domestic situations

Introduction: circa 1951

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur -
Date inclusion expires Expired

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also registered in: Costa Rica

General status:
Pesticide type Insecticide
Substance group Organochlorine
Substance origin Synthetic
Mode of action Persistent, non-systemic contact and stomach poison with some fumigant action. Is a chloride channel-blocking agent.
CAS RN 76-44-8
EC number 200-962-3
CIPAC number 36
US EPA chemical code 044801
Chiral molecule Chiral or specific isomer of chiral molecule
Chemical formula C10H5Cl7
SMILES ClC1(C(Cl)2Cl)C(C=CC3Cl)C3C2(Cl)C(Cl)=C1Cl
International Chemical Identifier (InChI) InChI=1/C10H5Cl7/c11-4-2-1-3-5(4)9(15)7(13)6(12)8(3,14)10(9,16)17/h1-5H
Structure diagram/image available? Yes
Molecular mass (g mol-1) 373.32
PIN (Preferred Identification Name) -
IUPAC name 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene
CAS name 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene
Other status information PIC Annex III; POP; LRTAP Annex 1; OSPAR soc; Severe Marine Pollutant; Rotterdam Convention (Class O)
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) 2A
Fungicide Resistance Classification (FRAC) Not applicable
Physical state White to tan coloured crystals
Related substances & organisms -

Formulations:
Property Value
Example manufacturers of products using this active
  • No longer produced
Example products using this active
  • Gold crest
  • Heptamul
  • Heptox
UK LERAP status No UK approval for use or outside scope
Formulation and application details No longer available.


ENVIRONMENTAL FATE

for heptachlor

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 0.056 G4 Low
Solubility - In organic solvents at 20oC (mg l-1) - - -
Melting point (oC) 95 V3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 2.75 X 1005 Calculated -
Log P 5.44 G4 High
Bulk density (g ml-1)/Specific gravity 1.58 L3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 53 G4 Intermediate state
Henry's law constant at 25oC (Pa m3 mol-1) 3.53 X 1002 L3 Volatile
Henry's law constant at 20oC (dimensionless) 4.47 X 10-02 Q2 Volatile
GUS leaching potential index -0.93 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 285 L3 Persistent
DT50 (lab at 20oC) - - -
DT50 (field) 250 F3 Persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Other sources: DT50 around 2 yrs (R3), 9-10 months (R3)
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 1 R3 Non-persistent
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - G3 Non-mobile
Koc 24000
Notes and range Other sources: 21878 mL/g (R3)
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 91/414 relevancy
heptachlor epoxide (Ref: ENT 25584) Soil     Not assessed under 91/414


ECOTOXICOLOGY

for heptachlor

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF 2430 R3 (whole body) Threshold for concern
CT50 (days) Not available -
Bioaccumulation potential - Calculated High
Mammals - Acute oral LD50 (mg kg-1) > 147 L3 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - L1 Rat -
(ppm diet) 5 -
Birds - Acute LD50 (mg kg-1) > 2000 L3 Anas platyrhynchos Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.007 L3 Oncorhynchus mykiss High
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.042 F4 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.027 F4 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (μg bee-1) > 0.526 F4 Contact High
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for heptachlor

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) > 147 L3 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) 195 R3 Rat -
Mammals - Inhalation LC50 (mg l-1) 2.0 R3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.0001 JMPR -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public Risk of exposure via food is now considered negligible
Occupational May be absorbed through intact skin
Examples of European MRLs (mg kg-1) Value -
Note For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

-

General human health issues Bioaccumulates
Liver toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General No information available
CLP classification 2013 -
EC Risk Classification Carcinogen category 3: R40
T - Toxic: R24/25, R33
N - Dangerous for the environment: R50, R53
EC Safety Classification S1/2, S36/37, S45, S60, S61
WHO Classification O - Obsolete substance
US EPA Classification (formulation) II - Warning - Moderately toxic
UN Number -
Waste disposal & packaging -


TRANSLATIONS

for heptachlor

Language Name
English heptachlor
French heptachlore
German Heptachlor
Danish heptachlor
Italian eptaclor
Spanish heptaclor
Greek heptachlor
Slovenian heptaklor
Polish heptachlor
Swedish -
Hungarian -
Dutch heptachloor

Record last updated: Tuesday 20 August 2013
Contact: aeru@herts.ac.uk