Hexazinone (Ref: DPX A3674)
Last updated: 17/01/2023
(Also known as: DPX-3674)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A broad-spectrum herbicide used to control many annual, biennial and perennial weeds.
Grasses; Broad-leaved weeds; Woody plants
Fruit; Sugarcane; Alfalfa; Forestry; Pastures; Rangeland; Fallow land
-
Current
1975, USA
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
-
Expired
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
None
C₁₂H₂₀N₄O₂
CN1C(=NC(=O)N(C1=O)C2CCCCC2)N(C)C
No data
CAWXEEYDBZRFPE-UHFFFAOYSA-N
InChI=1S/C12H20N4O2/c1-14(2)10-13-11(17)16(12(18)15(10)3)9-7-5-4-6-8-9/h9H,4-8H2,1-3H3
Yes
Herbicide
Triazinone herbicide
-
-
Synthetic
Non-selective with contact action, absorbed through the roots and foliage of plants. Inhibits photosynthesis (photosystem II).
51235-04-2
257-074-4
374
107201
39965
613-132-00-4
252.31
-
3-cyclohexyl-6-dimethylamino-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione
3-cyclohexyl-6-(dimethylamino)-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione
Potential groundwater contaminant; Chemical subject to PIC regulations
-
C1
5
Not applicable
Not applicable
-
Colourless crystals
DuPont AgroCare Makhteshim Agan Group FCC Ltd
Velpar Weed Killer Pronone Fertihexa Elinone
Available in a variety of formulations including wettable granules, suspension concentrates and tablets
33000
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
High
626000
Acetone
-
334000
Toluene
-
2146500
Methanol
-
837000
Benzene
-
113.5
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Decomposes on distillation
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
-
-
-
-
-
-
-
1.48 X 1001
Calculated
-
1.17
P4 P = Other governments and regulators 4 = Verified data
Low
-
-
-
-
-
-
1.25
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
2.2
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Weak base
0.03
Low volatility
1.10 X 10-07
Non-volatile
-
-
-
-
-
-
-
105
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Persistent
90
Moderately persistent
-
-
-
-
-
-
-
-
-
-
-
-
Other sources: DT₅₀ 30 (sand) - 180 (clay) days (R3); General literature DT₅₀ range 59-64 days (R3)
-
-
-
-
11.3
R4 R = Peer reviewed scientific publications 4 = Verified data
-
Published literature RL₅₀ range 10.5-12.0 days, 2 field crops, various matrices, n=2
56
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Stable
-
56
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Moderately persistent
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Mobile
54
Other sources: Koc 610 (P3)
-
-
-
-
-
-
-
4.43
Calculated
High leachability
2.15 X 1000
Calculated
-
-
Medium
Calculated
-
Mobile
Calculated
-
7
P4 P = Other governments and regulators 4 = Verified data
Low potential
Not available
-
-
-
-
Major fraction
-
-
Major fraction
-
-
Known groundwater metabolites
None
None
Terrestrial ecotoxicology
1690
Rat
Moderate
-
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Rat 2 year
-
> 200
-
-
-
-
> 2258
Colinus virginianus
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 100
Apis mellifera
Low
-
-
-
60
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 320
Oncorhynchus mykiss
Low
0.0855
P3 P = Other governments and regulators 3 = Unverified data of known source
Salmo salar
Moderate
> 85
Daphnia magna
Moderate
> 50
Daphnia magna LOEC
Low
-
-
-
-
-
-
-
-
-
-
-
-
> 0.072
Lemna minor 7 day
Moderate
0.0145
Pseudokirchneriella subcapitata
Moderate
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
1690
Rat
Moderate
5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rabbit
-
7.48
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
0.05
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
Highly toxic
No information available
Health: H302, H319 Environment: H400, H410
II (Moderately hazardous)
-
-
hexazinone
hexazinone
Hexazinon
hexazinon
esazinone
hexazinona
-
heksazynon
-
hexazinone
-
Record last updated:
17/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242