Icaridin (Ref: KBR 3023) |
![]() Last updated: 02/07/2019 |
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(Also known as: icaradine; picaradin; propidine; autan; hydroethyl isobutyl piperidine carboxylate) |
SUMMARY |
Icaridin is an insect repellant without EU regulatory approval for use. It has a high aquatic solubility and is volatile. Data is limited regarding its environmental persistence. It has a relatively low mammalian toxicity and a high potential to bioaccumulate. It is is not highly toxic to birds or fish. There are gaps in ecotoxicology and environmental fate data. |
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An insect repellant used for both human and animal applications to control a broad spectrum of insect pests | |
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Biting flies, Mosquitoes, Ticks, fleas | |
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Humans; Livestock | |
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Current | |
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2001, USA first registered |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Australia |
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Chemical structure |
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A molecule with 2 chiral centres | |
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C₁₂H₂₃NO₃ | |
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CCC(C)OC(=O)N1CCCCC1CCO | |
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No data | |
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QLHULAHOXSSASE-UHFFFAOYSA-N | |
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InChI=1S/C12H23NO3/c1-3-10(2)16-12(15)13-8-5-4-6-11(13)7-9-14/h10-11,14H,3-9H2,1-2H3 | |
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Yes |
General status |
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Insecticide, Repellent, Veterinary substance | |
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Piperidine | |
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970 g kg⁻¹ | |
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None declared by manufacturer; Chemistry suggests sec-butyl chloroformate & sec-butyl carbonic anhydride | |
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Synthetic | |
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Topically applied, repellent | |
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119515-38-7 | |
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423-210-8 | |
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740 | |
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070705 | |
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125098 | |
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229.32 | |
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- | |
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(RS)-sec-butyl (RS)-2-(2-hydroxyethyl)piperidine-1-carboxylate | |
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1-methylpropyl 2-(2-hydroxyethyl)-1-piperidinecarboxylate | |
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Not applicable | |
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Not applicable | |
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Not known | |
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Not applicable | |
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- | |
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Colourless, odourless liquid |
Formulations |
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Available in a variety of formulations including aerosol sprays, pump sprays and towelette wipes |
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8200 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
High | ||||||||
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Miscible | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Propanol4 = Verified data |
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Miscible | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Ethanol4 = Verified data |
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-170 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Freezing point3 = Unverified data of known source |
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296 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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375 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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1.70 X 1002 | Calculated | - | |||||||
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2.23 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Low | ||||||||
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1.04 | Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source |
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Not applicable | Q4 Q = Miscellaneous internet resources 4 = Verified data |
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No dissociation | |||||||||||
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0.034 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Low volatility | ||||||||
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Degradation |
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Stable | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Stable | |||||||
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Stable under normal environmental conditions | ||||||||||
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Soil adsorption and mobility |
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- | CA2 CA = Medical and toxicological databases and information systems e.g. TOXNET (click here ) 2 = Unverified data of unknown source |
Moderately mobile | |||||||
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Estimated | ||||||||||
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Fate indices |
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Cannot be calculated | - | - | |||||||||||||||||||||||||
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1.8 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) (whole body)4 = Verified data |
Low potential | |||||||
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ND | - | |||||||||
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2236 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat3 = Unverified data of known source |
Low | ||||||||
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100 | Q4 Q = Miscellaneous internet resources Rat4 = Verified data |
Moderate | |||||||
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> 5000 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Colinus virginianus4 = Verified data |
Low | ||||||||
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173 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss4 = Verified data |
Low | ||||||||
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50.1 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss4 = Verified data |
Low | ||||||||
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100 | Q2 Q = Miscellaneous internet resources Daphnia magna2 = Unverified data of unknown source |
Moderate | ||||||||
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103 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna3 = Unverified data of known source |
Low | ||||||||
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71.5 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Scenedemus subspicatus4 = Verified data |
Low | ||||||||
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54.8 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Scenedesmus subspicatus4 = Verified data |
Low | ||||||||
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General |
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High (class III) | - | - | ||||||||
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2236 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat3 = Unverified data of known source |
Low | ||||||||
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5000 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
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> 4.36 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
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Occupational exposure may occur through inhalation and dermal contact | ||||||||||
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Health issues |
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No further information available |
Handling issues |
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Not explosive or oxidising | |||
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Not classified: Obsolete | |||
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Not classified: Obsolete | |||
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Not classified: Obsolete | |||
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III/O (Slightly hazardous / Obsolete substance) | |||
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icaridin | ||
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icaridin | ||
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Icaridin | ||
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icaridin | ||
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icaridin | ||
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icaridin | ||
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ikarydyna | ||
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icaridin | ||
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Record last updated: | 02/07/2019 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |