Imazethapyr (Ref: AC 252925)
Last updated: 18/01/2023
(Also known as: CL 252925)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A herbicide used to control a variety of broad-leaved weeds and grasses in numerous crops
Barnyardgrass, Crabgrass, Cocklebur, Pigweeds, Stinkweed Nightshade, Wild mustard, Velvetleaf, Foxtail, Morning-glory
Soybeans; Peanuts; Beans and peas
-
Current
1989
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
-
Expired
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
A chiral molecule existing in the R- and S-forms, the R-isomer is considered to be the most biologically active.
C₁₅H₁₉N₃O₃
CCC1=CN=C(C(=C1)C(=O)O)C2=NC(C(=O)N2)(C)C(C)C
No data
XVOKUMIPKHGGTN-UHFFFAOYSA-N
InChI=1S/C15H19N3O3/c1-5-9-6-10(13(19)20)11(16-7-9)12-17-14(21)15(4,18-12)8(2)3/h6-8H,5H2,1-4H3,(H,19,20)(H,17,18,21)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
imazethapyr
-
Herbicide
Imidazolinone herbicide
-
-
Synthetic
Systemic with contact and residual activity. Inhibits plant amino acid synthesis - acetohydroxyacid synthase AHAS.
81335-77-5
617-222-4
700
128922
54740
No data found
289.33
-
5-ethyl-2-[(RS)-4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl]nicotinic acid
2-(4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl)-5-ethyl-3-pyridinecarboxylic acid
-
-
B
2
Not applicable
Not applicable
Many recorded cases, Amaranthus hybridus , Amaranthus lividus , Amaranthus palmeri
Colourless crystals
AgroCare BASF: Makhteshim Agan Group KingTai Chemicals Co.
Clearpath Newpath Pivot Pursuit Overtop
Usually supplied as an aqueous concentrate
1400
High
48200
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
105000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Methanol
-
5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Toluene
-
900
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Heptane
-
171
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Decomposes before boiling
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
180
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
3.09 X 1001
Calculated
-
1.49
Low
Insoluble
-
Observed in metabolism and farm animal feeding studies
-
1.11
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
2.1
-
pKa(2) 3.9
1.33 X 10-02
Low volatility
1.30 X 10-02
Non-volatile
-
-
-
-
-
-
-
90
Moderately persistent
513
Very persistent
51
Moderately persistent
-
-
-
-
-
-
-
-
-
Lab studies DT₅₀ range 126-900 days, field studies DT₅₀ range 14-290 days Northern USA and 7-19 days southern USA
-
-
-
-
15.2
R4 R = Peer reviewed scientific publications 4 = Verified data
-
Published literature RL₅₀ range 6.5-32.1 days, 6 field crops, various matrices, n=6
52
Stable
-
Stable
Stable
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Mobile
52
UK PSD lab studies 20-22 mL g⁻¹ silt loam soils; Other sources: 100 mL g⁻¹ (DW3)
-
-
-
-
-
-
-
3.90
Calculated
High leachability
9.67 X 10-01
Calculated
-
-
Medium
Calculated
-
Mobile
Calculated
-
1.6
Viscera
Low potential
Not available
-
None
Terrestrial ecotoxicology
> 5000
Rat
Low
818
Rat
Moderate
10000
-
-
-
-
> 2150
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Anas platyrhynchos
Low
-
-
-
-
-
-
10000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 100
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
> 24.6
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 340
Oncorhynchus mykiss
Low
97.0
P4 P = Other governments and regulators 4 = Verified data
Pimephales promelas
Low
> 1000
Daphnia magna
Low
103.0
P3 P = Other governments and regulators 3 = Unverified data of known source
Daphnia magna
Low
-
-
-
-
-
-
-
-
-
-
-
-
0.008
Lemna gibba
High
71
Raphidocelis subcapitata
Low
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 5000
Rat
Low
2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rabbit
-
3.27
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
0.44
UK ACP 1999
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B3 B = DNA damage/repair (EFSA database) 3 = Negative
; C3 C = Gene mutation (EFSA database) 3 = Negative
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
No further information available
Prevent generation of dust Corrosive
Environment: H400, H410
U (Unlikely to present an acute hazard)
-
-
imazethapyr
imazethapyr
Imazethapyr
imazethapyr
imazetapir
imazetapir
-
imazetapyr
-
-
-
Record last updated:
18/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242