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GET ADDITIONAL DATA HERE!

maneb (Ref: ENT 14875)
** manebe ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for maneb

Description: A fungicide used to control a wide range of diseases including blight, leaf spot, rust, downy mildew and scab

Example pests controlled: Early and late blights; Rust; Downy mildew; Leaf spot; Scab; Leaf moulds

Example applications: Fruits; Vegetables; Field crops including potatoes; Ornamentals

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1985

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Italy/UK
Date inclusion expires Expired
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C4H6MnN2S4
Canonical SMILES C(CNC(=S)[S-])NC(=S)[S-].[Mn+2]
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) VGMMANJYQVBVPU-UHFFFAOYSA-M
International Chemical Identifier (InChI) InChI=1S/C4H8N2S4.Mn/c7-3(8)5-1-2-6-4(9)10;/h1-2H2,(H2,5,7,8)(H2,6,9,10);/q;+2/p-2
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide
Substance group Carbamate
Minimum active substance purity 860 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Non-specific with protective action. Multi-site activity.
CAS RN 12427-38-2
EC number 235-654-8
CIPAC number 61
US EPA chemical code 014505
PubChem CID 3032581
Molecular mass (g mol-1) 265.30
PIN (Preferred Identification Name) -
IUPAC name manganese ethylenebis(dithiocarbamate) (polymeric)
CAS name ((2-((dithiocarboxy)amino)ethyl)carbamodithioato))(2-)-kS,kS')manganese
Other status information Marine Pollutant
Relevant Environmental Water Quality Standards UK Environment Agency non-statutory standard for the protection of aquatic life in freshwater and saltwater annual average 3 ug/L, max acceptable conc 30 ug/L
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) M3
Examples of recorded resistance -
Physical state Yellow powder
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • DuPont
  • Rohm & Haas
  • BASF
  • Rhone-Poulenc
Example products using this active
  • Manzate
  • Trimangol
  • Nespor
  • Manesan
UK LERAP status None
Formulation and application details Usually formulated as wettable powders and flowable suspensions.


ENVIRONMENTAL FATE

for maneb

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 178 A5 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 10 A5 - Ethyl acetate -
10 A5 - Acetone -
10 A5 - Heptane -
1.4 A5 - Octanol -
Melting point (oC) Decomposes before melting A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 198 L3 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 3.55 X 10-01 Calculated -
Log P -0.45 A5 Low
Bulk density (g ml-1)/Specific gravity 1.99 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 0.014 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.08 X 10-05 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -0.88 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 2.12 X 10-06 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 Maxima at 285nm A5 -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 1 A4 Non-persistent
DT50 (lab at 20oC) 0.1 A5 Non-persistent
DT50 (field) 7 A5 Non-persistent
DT90 (lab at 20oC) 51 A4 -
DT90 (field) 8.5 A5 -
DT50 modelling endpoint - - -
Note EU dossier Lab studies DT50 range 2-3.5 hours, DT90 ~7 weeks; field studies DT50 < 1 week
Dissipation rate RL50 on plant matrix Value 7.5 R4 -
Note Published literature RL50 range 2.4-17.7 days, 5 field & undercover grown crops, various matrices, n=6
Dissipation rate RL50 on and in plant matrix Value 2.8 R3 -
Note green bean leaves, n=1
Aqueous photolysis DT50 (days) at pH 7 Value Stable A5 -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 1.0 A5 Non-persistent
Note Not sensitive to pH at 25 degC
Water-sediment DT50 (days) 0.35 A5 Fast
Water phase only DT50 (days) 0.35 A5 Fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - DW3 Slightly mobile
Koc 2000
Notes and range -
Freundlich Kf 0.16 A5 Slightly mobile
Kfoc 1310
1/n -
Notes and range EU dossier Kfoc range 874-2127 mL/g
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
ethyleneurea This metabolite may cause environmental pollution, click here for further information Soil   0.204   Major fraction, Not relevant
ethylenethiourea This metabolite may cause environmental pollution, click here for further information Soil   0.638   Major fraction, Relevant
ethylene bisisothiocyanate sulphide This metabolite may cause environmental pollution, click here for further information Soil   0.128   Major fraction, Not relevant


ECOTOXICOLOGY

for maneb

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk A5 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 1467 A5 Anas platyrhynchos Moderate
Birds - Short term dietary (LC50/LD50) > 5000 mg kg feed-1 A5 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 0.20 A4 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.0065 A5 Pimephales promelas High
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0021 A5 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.0023 A5 Daphnia magna High
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 2.4 F3 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.007 A4 Pseudokirchneriella subcapitata, 120 hour High
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 100 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 89.5 A5 Moderate
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) 840 A5 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 8.0 A5 Eisenia foetida Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect Moderately harmful AA2 Typhlodromus pyri -
Other arthropod (2) LR50 g ha-1 - - -
% Effect 1500 A5 Aphidius rhopalosiphi -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 20 kg ha-1, 28 days
-
Mesocosm study data NOEAEC mg l-1 0.032 A5 whole system -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for maneb

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) 5.34 A5 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.05 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.2 A5 Rat -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.03 A5 Rat, SF=100 -
Dermal penetration studies (%) 0.2-0.4 A5 concentration dependent -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues IARC Group 3 carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive
Fire will produce irritating, corrosive and/or toxic gases
IMDG Transport Code is usually 4.2
CLP classification 2013 Health: H317, H319; H332; H361d
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Reproduction risk category 3: R63
Xn - Harmful: R20, R43
Xi - Irritant: R36
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S36/37, S46, S60, S61
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) IV - Caution - Not acutely toxic
UN Number Usually 2210
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for maneb

Language Name
English maneb
French manebe
German Maneb
Danish maneb
Italian maneb
Spanish maneb
Greek -
Slovenian maneb
Polish maneb
Swedish -
Hungarian -
Dutch -

Record last updated: Wednesday 23 May 2018
Contact: aeru@herts.ac.uk