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atrazine (Ref: G 30027)
** aneldazin ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

Atrazine is a herbicide that does not have EU approval for use. It has selective, systemic action with residual and foliar activity. It has a low aqueous solubility, it is non-volatile and, based on its physico-chemical properties there is some concern that it could leach to groundwater. It is generally not persistent in the field nor in aquatic systems. It is moderately toxic to mammals, is not expected to bioaccumulate and is a skin, eye and respiratory system irritant. It is moderately toxic to most aquatic life, earthworms and honeybees but presents less of a risk to birds.

GENERAL INFORMATION
for atrazine

Description: A triazine herbicide used pre- and post-emergence with restricted permitted uses to control broad-leaved weeds and grasses

Introduction: 1957

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur UK
Date inclusion expires Expired

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also registered in: Australia, USA

General status:
Pesticide type Herbicide
Substance group Triazine
Substance origin Synthetic
Mode of action Selective, systemic action with residual and foliar activity. Inhibits photosynthesis (photosystem II).
CAS RN 1912-24-9
EC number 217-617-8
CIPAC number 91
US EPA chemical code 080803
Chiral molecule No
Chemical formula C8H14ClN5
SMILES Clc1nc(nc(n1)NC(C)C)NCC
International Chemical Identifier (InChI) InChI=1/C8H14ClN5/c1-4-10-7-12-6(9)13-8(14-7)11-5(2)3/h5H,4H2,1-3H3,(H2,10,11,12,13,14)
Structure diagram/image available? Yes
Molecular mass (g mol-1) 215.68
PIN (Preferred Identification Name) 6-chloro-N2-ethyl-N4-(propan-2-yl)-1,3,5-triazine-2,4-diamine
IUPAC name 6-chloro-N2-ethyl-N4-isopropyl-1,3,5-triazine-2,4-diamine
CAS name 6-chloro-N-ethyl-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine
Other status information OSPAR soc; WFD pps; Potential groundwater contaminant
Herbicide Resistance Classification (HRAC) C1
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Physical state White crystals
Related substances & organisms

Formulations:
Property Value
Example manufacturers of products using this active
  • Syngenta
  • Bayer CropScience
  • Monsanto
  • Scotts
Example products using this active
  • Gesaprim
  • Fenamin
  • Atrazinax
  • Weedex
  • Primaze
  • Atratol
  • Radazine
UK LERAP status LERAP Category B
Formulation and application details Available in a variety of formulations including dry flowable, flowable liquid, liquid, water dispersible granules and wettable powders.


ENVIRONMENTAL FATE

for atrazine

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 35 B5 Low
Solubility - In organic solvents at 20oC (mg l-1) 24000 F4 - Ethyl acetate -
28000 F4 - Dichloromethane -
4000 F4 - Toluene -
110 F4 - n-Hexane -
Melting point (oC) 175.8 L3 -
Boiling point (oC) Decomposes before boiling F4 -
Degradation point (oC) - - -
Flashpoint (oC) Not expected to self ignite; Not highly flammable F4 -
Octanol-water partition coefficient at pH 7, 20oC P 5.01 X 1002 Calculated -
Log P 2.7 B5 Moderate
Bulk density (g ml-1)/Specific gravity 1.23 F4 -
Dissociation constant (pKa) at 25oC 1.7 B5 -
Note: Very weak base
Vapour pressure at 25oC (mPa) 0.039 B5 Non-volatile
Henry's law constant at 25oC (Pa m3 mol-1) 1.50 X 10-04 L3 Non-volatile
Henry's law constant at 20oC (dimensionless) 1.20 X 10-07 K3 Non-volatile
GUS leaching potential index 3.30 Calculated High leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 4.09 X 10-01 Calculated -
Note -
Potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 75 B5 Laboratory Moderately persistent
DT50 (lab at 20oC) 66 B4 Moderately persistent
DT50 (field) 29 B4 Non-persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Lab studies DT50 range 28-150 days, field studies DT50 range 6-108 days (USA); Other sources: DT50 6-10 weeks (R3), 146 days at 25 DegC (R3)
Aqueous photolysis DT50 (days) at pH 7 Value 2.6 B5 Moderately fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 86 K4 Moderately persistent
Note Rapidly hydrolysed in strong acids and alkalis and at elevated temperatures
Water-sediment DT50 (days) 80 K4 Moderately fast
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - G3 Moderately mobile
Koc 100
Notes and range Other sources: 89-513 mL/g (R3), Log Koc 2.00 at 25 DegC (R4)
Freundlich Kf 3.2 R4 Moderately mobile
Kfoc 174
1/n 1.07
Notes and range Literature data: Kf range 1.3-6.3 mL/g, kfoc range 70-429 mL/g, 1/n range 1.04=1.10, Soils = 13
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 91/414 relevancy
6-deisopropyl atrazine (Ref: G-28279) Soil   0.33   Major, Relevant
deethylatrazine (Ref: G-30033) Soil   0.21   Major, Relevant
2-hydroxyatrazine (Ref: G-34048) Soil     Non Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
deisopropyldeethylhydroxyatrazine
(Ref: G-17791)
- Soil 0.004 -
deisopropylhydroxyatrazine
(Ref: G-17792)
- Soil 0.08 -
deethylhydroxyatrazine
(Ref: G-17794)
- Soil 0.08 -
deisopropyldeethylatrazine
(Ref: G-28273)
- Soil 0.08 -


ECOTOXICOLOGY

for atrazine

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF 4.3 P4 (Other literature Log BCF range 0.98-2.5 (R3)) Low potential
CT50 (days) Not available -
Bioaccumulation potential - Calculated Low
Mammals - Acute oral LD50 (mg kg-1) 1869 B5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - B3 Rat -
(ppm diet) 200 -
Birds - Acute LD50 (mg kg-1) 4237 B5 Coturnix japonica Low
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 4.5 B5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 2 J4 Oncorhynchus mykiss -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 85 B3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.25 F3 Daphnia magna, LOEC -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 1.0 F4 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) 1.0 F3 Chironomus riparius, 1 day Moderate
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.019 F3 Lemna gibba Moderate
Algae - Acute 72 hour EC50, growth (mg l-1) 0.059 B3 Raphidocelis subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) 0.1 F3 Green algae Moderate
Honeybees - Acute 48 hour LD50 (μg bee-1) 100 B5 Oral Moderate
Earthworms - Acute 14 day LC50 (mg kg-1) 79 B5 Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect Harmless AA2 Typhlodromus pyri Harmless
Other arthropod (2) LR50 g ha-1 - - -
% Effect Harmless AA2 Chrysoperla carnea Harmless
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for atrazine

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) 1869 B5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 3100 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 5.8 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.02 JMPR 2007 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.1 JMPR 2007 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.01 BA5; EU 1998 -
Dermal penetration studies (%) 10 BA5; EU 1998 -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational May be absorbed from the lungs or through intact skin
Examples of European MRLs (mg kg-1) Value Vegetables and fruit: 0.05: Cereal grains: 0.1
Note Current May 2007.
For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

General human health issues May cause coma, circulatory collapse and gastric bleeding
May cause renal failure

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General Avoid the formation of dust
Powders may become explosive under certain conditions
CLP classification 2013 -
EC Risk Classification Xn - Harmful: R48/22, R43
N - Dangerous for the environment: R50, R53
EC Safety Classification S2, S36/37, S61, S60
WHO Classification III - Slightly hazardous
US EPA Classification (formulation) III - Caution - Slightly toxic
UN Number -
Waste disposal & packaging -


TRANSLATIONS

for atrazine

Language Name
English atrazine
French atrazine
German Atrazin
Danish atrazin
Italian atrazina
Spanish atrazina
Greek atrazine
Slovenian atrazin
Polish atrazyna
Swedish -
Hungarian atrazine
Dutch atrazine

Record last updated: Wednesday 22 October 2014
Contact: aeru@herts.ac.uk