Methoprene (Ref: OMS 1697) |
![]() Last updated: 27/11/2019 |
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(Also known as: SAN 800; ZR-515) |
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A general purpose insect growth regulator used to control a range of pests including | |
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Diptera, Hymenoptera, Lepidoptera and Coleoptera such as fleas, moths, mosquitoes and beetles | |
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Livestock pest control; Pest control on domestic pets; Food storage | |
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Current | |
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1975, USA |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Sweden | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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- | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Australia |
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Chemical structure |
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A chiral molecule existing as the R-form (cis) and the S-form (trans). The technical substance is an isomeric mixture but it is the S-form which is more biologically active. | |
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C₁₉H₃₄O₃ | |
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CC(C)OC(=O)C=C(C)C=CCC(C)CCCC(C)(C)OC | |
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CC(C)OC(=O)/C=C(\C)/C=C/CC(C)CCCC(C)(C)OC | |
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NFGXHKASABOEEW-LDRANXPESA-N | |
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InChI=1S/C19H34O3/c1-15(2)22-18(20)14-17(4)11-8-10-16(3)12-9-13-19(5,6)21-7/h8,11,14-16H,9-10,12-13H2,1-7H3/b11-8+,17-14+ | |
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Yes |
General status |
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Insecticide, Veterinary substance | |
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Juvenile hormone mimic (terpene) | |
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Synthetic | |
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Contact and stomach action, acts by mimicing the action of the juvenile hormone keeping the insect in an immature state | |
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40596-69-8 | |
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254-993-2 | |
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414 | |
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105401 | |
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5366546 | |
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310.47 | |
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- | |
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isopropyl (E,E)-(RS)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate | |
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(E,E)-1-methylethyl (2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate | |
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- | |
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- | |
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Not applicable | |
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Not applicable | |
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7A | |
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Not applicable | |
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Culex pipiens pipiens, Drosophila melanogaster, Ochlerotatus nigromaculis | |
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Yellow to amber coloured liquid |
Formulations |
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Usually supplied as an emulsifiable concentrate, suspension concentrate, briquettes or bait |
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0.52 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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136 | L3 L = Pesticide manuals and hard copy reference books / other sources (closed cup)3 = Unverified data of known source |
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1.00 X 1005 | Calculated | - | |||||||
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5 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
High | ||||||||
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0.92 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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3.16 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Low volatility | ||||||||
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0.886 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderately volatile | ||||||||
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Degradation |
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10 | B3 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 3 = Unverified data of known source |
Non-persistent | |||||||
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10 | B3 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 3 = Unverified data of known source |
Non-persistent | ||||||||
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1.4 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 0.5-2.4 days, 2 field crops, various matrices, n=2 | ||||||||||
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1 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Moderately fast | |||||||
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Stable | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes |
Stable | |||||||
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Soil adsorption and mobility |
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- | US3 US = US Dept of Agriculture National Resources Conservation Service - various datasheets, databases and online sources 3 = Unverified data of known source |
Slightly mobile | |||||||
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2535 | ||||||||||
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Fate indices |
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0.60 | Calculated | Low leachability | ||||||||||||||||||||||||||
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9.19 X 10-03 | Calculated | - | |||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Slightly mobile | Calculated | - |
Other known metabolites |
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7-methoxycitronellic acid | - | Water (Aerobic) | - | - |
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3400 | R4 R = Peer reviewed scientific publications Edible4 = Verified data |
Threshold for concern | |||||||
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Not available | - | |||||||||
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> 34600 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
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- | L2 L = Pesticide manuals and hard copy reference books / other sources Rat 2 year2 = Unverified data of unknown source |
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> 5000 | - | |||||||||
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> 2250 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Anas platyrhynchos5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 0.76 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.089 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
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0.051 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna LOEC3 = Unverified data of known source |
Moderate | ||||||||
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0.106 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Americamysis bahia3 = Unverified data of known source |
Moderate | ||||||||
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1.33 | L3 L = Pesticide manuals and hard copy reference books / other sources Scenedemus subspicatus3 = Unverified data of known source |
Moderate | ||||||||
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2.0 | Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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> 34600 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
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2000 | L3 L = Pesticide manuals and hard copy reference books / other sources Rabbit3 = Unverified data of known source |
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210 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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0.09 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) JMPR 19873 = Unverified data of known source |
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None allocated | F5 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) JMPR 20015 = Verified data used for regulatory purposes |
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Health issues |
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No further information available |
Handling issues |
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No information available | |||
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Health: H315, H335 Environment: H400, H410 |
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Xi - Irritant: R36/37/38 N - Dangerous for the environment: R51/53 |
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S26, S36, S60, S61 | |||
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U (Unlikely to present an acute hazard) | |||
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methoprene | ||
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méthoprène | ||
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Methoprene | ||
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methopren | ||
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metoprene | ||
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metoprene | ||
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metopren | ||
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Record last updated: | 27/11/2019 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |