Naptalam (Ref: ACP 322)
Last updated: 23/01/2023
(Also known as: alanap; naptalam-sodium; naphthalam)
Naptalam is a broad-spectrum herbicide. It is usually used as the sodium salt as this is more soluble. Whilst naptalam is not particularly toxic to humans its major metabolite 1-naphthylamine is a carcinogen. Its environmental fate is pH sensitive. It may pose a threat to groundwaters. Virtually non toxic to mammals, birds, honeybees and most aquatic species. No data for eathworms has been identified.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A pre-emergence herbicide used for the control of a wide range of weeds and grasses in food and non-food crops
Annual broad-leaved weeds; Grasses
Soybean; Peanuts; Cucumbers; Melons; Curcubits; Cranberries; Woody ornamentals
-
Current
1955
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Expired
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
None
C₁₈H₁₃NO₃
C1=CC=C2C(=C1)C=CC=C2NC(=O)C3=CC=CC=C3C(=O)O
No data
JXTHEWSKYLZVJC-UHFFFAOYSA-N
InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
naptalam
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Herbicide
Phthalamate compound; Amide herbicide
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-
Synthetic
Selective, absorbed by roots and to a lesser extent foliage. Inhibits indolylacetic acid transport.
132-66-1
625-029-1
None allocated
030702
8594
No data found
291.30
-
N-1-naphthylphthalamic acid
2-[(1-naphthalenylamino)carbonyl]benzoic acid
Potential groundwater contaminant
-
P
19
Not applicable
Not applicable
-
Crytalline solid
Ancrack Klean Krop Rescue Alanap Grelutin
Available as liquids for dilution and in granular formulations.
200
Moderate
5900
Acetone
-
20900
Methanol
-
400
Xylene
-
Insoluble
Hexane
-
185
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
2.63 X 1005
Calculated
-
5.42
High
-
-
-
-
-
-
1.36
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
4.6
-
Weak acid
0.133
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
1.94 X 1002
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Volatile
-
-
-
-
-
-
-
36.7
Moderately persistent
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Best available data US EPA; Other sources: DT₅₀ 36.7 days (DW2)
-
-
-
-
-
-
-
-
6.2
Moderately fast
-
2.9
Non-persistent
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Mobile
20
Best available data
-
-
-
-
-
-
-
4.22
Calculated
High leachability
1.24 X 1000
Calculated
-
-
Low
Calculated
-
Mobile
Calculated
-
157
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
Estimated
Threshold for concern
Not available
-
Known soil and groundwater metabolites
None
1-naphthylamine Note: Carcinogenic
-
-
-
-
Terrestrial ecotoxicology
1770
Rat
Moderate
30
L1 L = Pesticide manuals and hard copy reference books / other sources 1 = Estimated data with little or no verification
Rat
High
-
-
-
-
-
> 4640
Anas platyrhynchos
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 113.2
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 76.1
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
> 118.5
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 1.0
P3 P = Other governments and regulators 3 = Unverified data of known source
Pseudokirchneriella subcapitata
Low
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
1770
Rat
Moderate
2000
Rabbit
-
> 2.07
Rat
-
-
-
-
0.05
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
?Possibly, status not identified
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
Possible liver toxicant
No information available
Health: H302 Environment: H412
U (Unlikely to present an acute hazard)
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naptalam
naptalame
Naptalam
naptalam
naptalam
naptalam
-
naptalam
-
naptalam
-
Record last updated:
23/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242