| omethoate (Ref: ENT 25776) |
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GENERAL INFORMATION 
for omethoate
Description: An insecticide and acaricide to control a wide range of pests on fruit, hops and other crops. Also a pesticide transformation product
Example pests controlled: Aphids; Mites; Caterpillars; Beetles; Mealybugs; Scale
Example applications: Fruit including citrus, apples, plum; Hops; Sugarbeet; Potatoes; Cereals; Ornamentals
Efficacy & activity: -
Availability status: Current
Introduction & key dates: circa 1960
EC Regulation 1107/2009 (repealing 91/414):
| Status | Not approved |
| Dossier rapporteur/co-rapporteur | Not applicable |
| Date inclusion expires | Expired |
| EU Candidate for substitution (CfS) | - |
| Listed in EU database | Yes |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
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Also used in: Australia
Chemical structure:
| Isomerism | None |
| Chemical formula | C5H12NO4PS |
| Canonical SMILES | CNC(=O)CSP(=O)(OC)OC |
| Isomeric SMILES | No data |
| International Chemical Identifier key (InChIKey) | PZXOQEXFMJCDPG-UHFFFAOYSA-N |
| International Chemical Identifier (InChI) | InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) |
| 2D structure diagram/image available? | Yes |
General status:
| Pesticide type | Insecticide, Acaricide, Metabolite | |||
| Metabolite Type | Soil; Groundwater; Surface water; Sediment; Air | |||
| Substance group | Organophosphate | |||
| Minimum active substance purity | - | |||
| Known relevant impurities | - | |||
| Substance origin | Synthetic | |||
| Mode of action | Systemic with contact and stomach action. Cholinesterase inhibitor. | |||
| CAS RN | 1113-02-6 | |||
| EC number | 214-197-8 | |||
| CIPAC number | 202 | |||
| US EPA chemical code | - | |||
| PubChem CID | 14210 | |||
| Molecular mass (g mol-1) | 213.2 | |||
| PIN (Preferred Identification Name) | - | |||
| IUPAC name | 2-dimethoxyphosphinoylthio-N-methylacetamide | |||
| CAS name | O,O-dimethyl S-(2-(methylamino)-2-oxoethyl) phosphorothioate | |||
| Other status information | Chemical subject to PIC regulations | |||
| Relevant Environmental Water Quality Standards | UK Statutory standard for the protection of aquatic life in surface waters: 0.01 ug/L | |||
| Herbicide Resistance Classification (HRAC) | Not applicable | |||
| Herbicide Resistance Classification (WSSA) | Not applicable | |||
| Insecticide Resistance Classification (IRAC) | 1B | |||
| Fungicide Resistance Classification (FRAC) | Not applicable | |||
| Examples of recorded resistance | Leptinotarsa decemlineata Aonidella aurantii Aphis gossypii Macrosiphum avenae Myzus persicae many others |
|||
| Physical state | Colourless liquid | |||
| Related substances & organisms | - | |||
Can be a metabolite of:
| Parent | Formation medium | Estimated maximum occurrence fraction | 1107/2009 relevancy |
|
| dimethoate | Soil | 0.150 | Major fraction, Not relevant | |
Formulations:
| Property |
Value | |||
| Example manufacturers & suppliers of products using this active now or historically |
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| Example products using this active |
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| UK LERAP status | No UK approval for use as a pesticide under EC Regulation 1107/2009 | |||
| Formulation and application details | Usually supplied as a soluble concentrate or emulsifiable concentrate. | |||
ENVIRONMENTAL FATE
for omethoate
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | 500000 | A5 | High | |
| Solubility - In organic solvents at 20oC (mg l-1) | Miscible | L3 - Acetone | - | |
| Miscible | L3 - Methanol | - | ||
| Melting point (oC) | -28 | L3 - Solidifies | - | |
| Boiling point (oC) | 135 | V3 | - | |
| Degradation point (oC) | - | - | - | |
| Flashpoint (oC) | 128 | L3 | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | 1.26 X 10-01 | Calculated | - |
| Log P | -0.9 | A5 | Low | |
| Bulk density (g ml-1)/Specific gravity | 1.32 | B5 | - | |
| Dissociation constant (pKa) at 25oC | - | - | - | |
| Note: | ||||
| Vapour pressure at 20oC (mPa) | 19.0 | A5 | Highly volatile | |
| Henry's law constant at 25oC (Pa m3 mol-1) | 4.62 X 10-09 | V3 | Non-volatile | |
GUS leaching potential index  |
-2.38 | Calculated | Low leachability | |
| SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | 8.00 X 10-05 | Calculated | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | Low | |
| Maximum UV-vis absorption L mol-1 cm-1 | Neutral soln: 194.4nm=6366.1 Acid soln: 207.5nm=2401.2 Basic soln: 233.5nm=3020.7 |
A5 | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
General biodegradability | - |
| Soil degradation (days) (aerobic) | DT50 (typical) | 0.1 |
A5 | Non-persistent |
| DT50 (lab at 20oC) | 0.1 | A5 | Non-persistent | |
| DT50 (field) | 14 | B5 | Non-persistent | |
| DT90 (lab at 20oC) | 0.6 | A5 | - | |
| DT90 (field) | - | - | - | |
| DT50 modelling endpoint | - | - | - | |
| Note | EU 2017 dossier Lab studies Dt50 range 0.1-0.3 days, DT90 range 0.1-1.2 days, Soils=3 | |||
| Dissipation rate RL50 on plant matrix | Value | - | - | - |
| Note | - | |||
| Dissipation rate RL50 on and in plant matrix | Value | 1.7 | R4 | - |
| Note | Published literature RL50 range 1.3-2.1 days, wheat, various matrices, n=3 | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | Stable | B4 | - |
| Note | - | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | 17 | B5 | Non-persistent |
| Note | - | |||
| Water-sediment DT50 (days) | 4.5 | K4 | Fast | |
| Water phase only DT50 (days) | - | - | - | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | 0.53 | A5 | Mobile |
| Koc | 41.3 | |||
| Notes and range | EU dossier Kd range 0.20-0.99 mL/g, Koc range16-87 mL/g, Soils=3 | |||
| Freundlich | Kf | - | - | - |
| Kfoc | - | |||
| 1/n | - | |||
| Notes and range | - | |||
| pH sensitivity | - | |||
Other known metabolites:
| Metabolite name and reference | Aliases | Formation medium / Rate | Estimated maximum occurrence fraction | Metabolising enzymes |
| dimethylthiophosphate | DMTP | Mammals | - | - |
| dimethylphosphate | DMP | Mammals | - | - |
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF (l kg-1) | 75 | Q2 Estimated | Low potential |
| CT50 (days) | Not available | - | ||
| Mammals - Acute oral LD50 (mg kg-1) | 50.0 | F4 Rat | High | |
| Mammals - Short term dietary NOEL | (mg kg-1) | - | B5 Rat | - |
| (ppm diet) | 0.5 | - | ||
| Birds - Acute LD50 (mg kg-1) | 9.9 | A5 Colinus virginianus | High | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | 9.1 | B5 Oncorhynchus mykiss | Moderate | |
| Fish - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | 0.022 | B5 Daphnia magna | High | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | 0.000004 | P3 Unknown species | High | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Non-target plants | - | - | - | |
| - | - | - | ||
| Algae - Acute 72 hour EC50, growth (mg l-1) | 167.5 | B5 Scenedemus subspicatus | Low | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | - | - | - | |
| Honeybees | Contact acute 48 hour LD50 (μg bee-1) | - | - | - |
| Oral acute 48 hour LD50 (μg bee-1) | 0.048 | B5 | High | |
| Unknown mode acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Earthworms - Acute 14 day LC50 (mg kg-1) | 46 | B5 Eisenia andrei | Moderate | |
| Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms - e.g. Collembola | LR50 / EC50 / NOEC / % Effect | - | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
HUMAN HEALTH AND PROTECTION
for omethoate
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Threshold of Toxicological Concern (Cramer Class) |
High (class III) | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | 50.0 | F4 Rat | High | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | 145.0 | L3 Rat | - | |
| Mammals - Inhalation LC50 (mg l-1) | 0.3 | L3 Rat | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | 0.0003 | BA5; EU 2006 | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | 0.002 | BA5; EU 2006 | - | |
| AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | 0.0003 | BA5; EU 2006 | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | List I; List II | - | - | |
| Exposure Limits | - | - | - | |
| Exposure Routes | Public | - | ||
| Occupational | Occupational exposure may occur through inhalation and dermal contact | |||
| European MRLs | Click here for the EU MRL pesticide database | |||
| Drinking Water Standards | - | - | - | |
| Drinking Water MAC (μg l-1) | - | - | - | |
Health issues:
| Carcinogen | Mutagen | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
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| Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
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| General human health issues | Toxic if swallowed May cause cyanosis |
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: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found
Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| General |
Flammable | |||
| CLP classification 2013 | Health: H301, H312 Environment: H400 |
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| EC Risk Classification |
T - Toxic: R25 Xn - Harmful: R21 N - Dangerous for the environment: R50 |
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| EC Safety Classification |
S1/2, S23, S36/37, S45, S61 | |||
| WHO Classification | Ib | - | Highly hazardous | |
| US EPA Classification (formulation) | I | - | Danger - Highly toxic | |
| UN Number | 3018 | |||
| Waste disposal & packaging |
- | |||
| Language | Name |
| English | omethoate |
| French | omethoate |
| German | Omethoat |
| Danish | omethoate |
| Italian | ometoato |
| Spanish | ometoato |
| Greek | - |
| Slovenian | ometoat |
| Polish | ometoat |
| Swedish | - |
| Hungarian | - |
| Dutch | - |
Record last updated: Thursday 24 May 2018
Contact: aeru@herts.ac.uk