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oxadiazon (Ref: RP 17623 )
** oxydiazon ** oxadiazo ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for oxadiazon

Description: A pre-emergent or early post-emergent herbicide used to control bindweed and some annual broad-leaved weeds in food and non-food situations

Example pests controlled: Crabgrass; Annual bluegrass; Goosegrass; Buttonweed; Annual sedge

Example applications: Turf, sports greens & ornamental grass; Non-cropped areas including playgrounds, roadsides; cemeteries; Ornamental shrubs, Vines; Trees

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1969, first reported

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Italy/Spain
Date inclusion expires 31/12/2018
EU Candidate for substitution (CfS) Yes - two 'Persistent-Bioaccumulative-Toxic' criteria
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C15H18Cl2N2O3
Canonical SMILES CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) CHNUNORXWHYHNE-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Oxidiazole
Minimum active substance purity -
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Selective with contact action. Inhibits protoporphyrinogen oxidase, leading to irreversible cell membrane damage.
CAS RN 19666-30-9
EC number 243-215-7
CIPAC number 213
US EPA chemical code 109001
PubChem CID 29732
Molecular mass (g mol-1) 345.2
PIN (Preferred Identification Name) -
IUPAC name 5-tert-butyl-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol-2(3H)-one
CAS name 3-(2,4-dichloro-5-(1-methylethoxy)phenyl)-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) E
Herbicide Resistance Classification (WSSA) 14
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state Colourless crystals
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer
  • Certis
  • Clayton
  • Standon
  • Rhone Poulenc
Example products using this active
  • Ronstar 2G
  • Ronstar Liquid
  • Standon Roxx L
UK LERAP status None
Formulation and application details Often supplied as an emulsifiable concentrate or as dry granules that are mixed with compost.


ENVIRONMENTAL FATE

for oxadiazon

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 0.57 A5 Low
Solubility - In organic solvents at 20oC (mg l-1) 350000 A4 - Acetone -
1000000 C4 - Benzene -
350000 A4 - Toluene -
122400 A4 - Methanol -
Melting point (oC) 88.5 A5 -
Boiling point (oC) 282.1 A5 -
Degradation point (oC) - - -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 2.14 X 1005 Calculated -
Log P 5.33 A5 High
Bulk density (g ml-1)/Specific gravity - - -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 0.67 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 3.80 X 10-02 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 2.40 Calculated Transition state
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.47 X 10-01 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution: 208.5nm = 35843, 292nm = 3283; [Acidic solution: 208.5nm = 34776, 292.5nm = 3216; [Basic solution: 218nm = 20718, 293nm = 4286 A5 -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 502 A5 Very persistent
DT50 (lab at 20oC) 502 A5 Very persistent
DT50 (field) 165 A5 Persistent
DT90 (lab at 20oC) - - -
DT90 (field) 545 A5 -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 118-825 days, field studies DT50 range 90-330 days, DT90 range 298-1085 days; Other sources: DT50 60 days (DW4)
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value 4.3 R3 -
Note Grape berries, n=1
Aqueous photolysis DT50 (days) at pH 7 Value 5.9 A4 Moderately fast
Note DT50 26.3 hrs at pH 9 sterile water - equivalent to 5.9 days at 40 deg N, 2.2 days sterile pond water
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 31 A5 Moderately persistent
Note Stable pH 4 to pH 7, at 25 degC for 31 days, DT50 11.7 days at pH 9, 20 degC
Water-sediment DT50 (days) 126.5 A5 Slow
Water phase only DT50 (days) 17.9 A5 Slow

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - DW3 Slightly mobile
Koc 3200
Notes and range -
Freundlich Kf 35.9 A5 Slightly mobile
Kfoc 1294
1/n 0.905
Notes and range EU dossier Kf range 12.73-62.15 mL/g, foc range 979-1527 mL/g, 1/n range 0.855-0.958; Other studies: Mean of 3 soils. Ando soil OC=5.2% Kf=150; Gray lowland soil OC=1.4% Kf=120; Light Ando soil OC=1.1% kf=100.
pH sensitivity No

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
2,4-dichloro-1-(propan-2-yloxy)benzene
(Ref: AE 0592465)
2,4-dichlorophenyl propan-2-yl ether Water; Sediment - -
5-tert-butyl-3-(2,4-dichloro-5-hydroxyphenyl)-1,3,4-oxadiazol-2(3H)-one
(Ref: AE 0608021)
- Water; Plant - -
N'-[2,4-dichloro-5-(propan-2-N'-[2,4-dichloro-5-(propan-2-dimethylpropanehydrazide
(Ref: AE 0608022)
- Water; Soil (Anaerobic); Sediment - -
N-[6-chloro-2-oxo-5-(propan-2-yloxy)-1,3-benzoxazol-3(2H)-yl]-2,2-dimethylpropanamide
(Ref: AE 0608033)
- Water (Photolysis) - -
(Ref: AE 0608035) - Water (Photolysis) - -
2-{4-[2,4-dichloro-5-(propan-2-yloxy)phenyl]-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl}-2-methylpropanoic acid
(Ref: AE 0616182)
- Plant - -
5-tert-butyl-3-(2,4-dichloro-5-methoxyphenyl)-1,3,4-oxadiazol-2(3H)-one
(Ref: AE 0618784)
- Plant - -
3-[2,4-dichloro-5-(propan-2-yloxy)phenyl]-5-(1-hydroxy-2-methylpropan-2-yl)-1,3,4-oxadiazol-2(3H)-one
(Ref: AE 0618785)
- Plant - -
2,2-dimethyl-N-(6-methyl-2-oxo-6,7-dihydrofuro[3',2':4,5]benzo[1,2-d]oxazol-3-yl)propionamide
(Ref: AE 1117150)
- Water (Photolysis) - -
(Ref: AE 1117815) - Water (Photolysis) - -


ECOTOXICOLOGY

for oxadiazon

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 243 A5 Threshold for concern
CT50 (days) 2.5 -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 10 -
Birds - Acute LD50 (mg kg-1) > 2150 A5 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) > 5000 mg/Kg diet A5 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 1.2 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.00088 A4 Oncorhynchus mykiss High
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 2.4 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.03 A5 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.23 F3 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.057 A5 Lemna gibba Moderate
Non-target plants 20.2 A5 Tomato
Vegetative vigour ER50
as g/ha
-
39.23 A5 Cucumber
Seedling emergence, ER50
as g/ha
-
Algae - Acute 72 hour EC50, growth (mg l-1) 0.004 A5 Scenedemus subspicatus High
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 100 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 110.5 A5 Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 500 A5 Eisenia foetida, corr Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 10.0 A5 Eisenia foetida Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 875 A5 Aphidius rhopalosiphi -
% Effect - - -
Other arthropod (2) LR50 g ha-1 150 A5 Typhlodromus pyri -
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effectffect
A5
Dose: 6 L product ha-1
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for oxadiazon

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 2.77 A5 Rat (aerosol) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.0036 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.12 A5 Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.05 A5 Rat, SF=100 -
Dermal penetration studies (%) 2-3 A5 -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Negligible risk to bystanders
Occupational Use of PPE/PPC recommended
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; A5 Calc MAC=11 μg l-1 -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Possible liver toxicant
May cause anaemia
USEPA - probable human carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is variable depending upon product, often either 3 or 9
CLP classification 2013 Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Reproduction risk category 3: R62
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S60, S61
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) IV - Caution - Not acutely toxic
UN Number Variable with product, usually 1993 or 3077
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for oxadiazon

Language Name
English oxadiazon
French oxadiazon
German Oxadiazon
Danish oxadiazon
Italian oxadiazon
Spanish oxadiazon
Greek -
Slovenian oksadiazon
Polish oksadiazon
Swedish -
Hungarian -
Dutch -

Record last updated: Wednesday 31 October 2018
Contact: aeru@herts.ac.uk