promecarb (Ref: SN 34615) ** SSI 0792 ** Translations

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GENERAL INFORMATION
for promecarb

Description: An obsolete phenyl methylcarbamate insecticide once used to combat foliage and fruit eating insects

Introduction: 1965, first reported

EC Regulation 1107/2009 (repealing 91/414):

Status	Not approved
Dossier rapporteur/co-rapporteur	-
Date inclusion expires	Expired

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:

Pesticide type	Insecticide
Substance group	Carbamate
Substance origin	Synthetic
Mode of action	Systemic. Cholinesterase inhibitor. Rapid knock down with contact and stomach action.
CAS RN	2631-37-0
EC number	220-113-0
CIPAC number	8258
US EPA chemical code	271400
Chiral molecule	No
Chemical formula	C12H17NO2
SMILES	CC1=CC(=CC(=C1)OC(=O)NC)C(C)C
International Chemical Identifier key (InChIKey)	DTAPQAJKAFRNJB-UHFFFAOYSA-N
International Chemical Identifier (InChI)	InChI=1S/C12H17NO2/c1-8(2)10-5-9(3)6-11(7-10)15-12(14)13-4/h5-8H,1-4H3,(H,13,14)
Structure diagram/image available?	Yes
Molecular mass (g mol-1)	207.3
PIN (Preferred Identification Name)	-
IUPAC name	5-methyl-m-cumenyl methylcarbamate
CAS name	3-methyl-5-(1-methylethyl)phenyl methylcarbamate
Other status information	Marine Pollutant
Herbicide Resistance Classification (HRAC)	Not applicable
Herbicide Resistance Classification (WSSA)	Not applicable
Insecticide Resistance Classification (IRAC)	1A
Fungicide Resistance Classification (FRAC)	Not applicable
Physical state	Colourless crystalline solid
Related substances & organisms	-

Formulations:

Property	Value
Example manufacturers & suppliers of products using this active	AgrEvo Schering AG
Example products using this active	Carbamult
UK LERAP status	No UK approval for use or outside scope
Formulation and application details	-

ENVIRONMENTAL FATE
for promecarb

Property		Value	Source/Quality Score/Other Information	Interpretation
Solubility - In water at 20oC (mg l-1)		91	H4	Moderate
Solubility - In organic solvents at 20oC (mg l-1)		-	-	-
Melting point (oC)		87	L3	-
Boiling point (oC)		-	-	-
Degradation point (oC)		-	-	-
Flashpoint (oC)		-	-	-
Octanol-water partition coefficient at pH 7, 20oC	P	1.26 X 1003	Calculated	-
	Log P	3.1	V3	High
Bulk density (g ml-1)/Specific gravity		-	-	-
Dissociation constant (pKa) at 25oC		-	-	-
		Note:
Vapour pressure at 25oC (mPa)		4	H4	Intermediate state
Henry's law constant at 25oC (Pa m3 mol-1)		9.10 X 10-03	H4	Non-volatile
Henry's law constant at 20oC (dimensionless)		3.74 X 10-06	Calculated	Moderately volatile
GUS leaching potential index		1.98	Calculated	Transition state
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate	Value	6.26 X 10-02	Calculated	-
	Note	-
Potential for particle bound transport index		-	Calculated	Low
Maximum UV-vis absorption L mol-1 cm-1		-	-	-
Surface tension (mN m-1)		-	-	-

Degradation:

Property		Value	Source/Quality Score/Other Information	Interpretation
Soil degradation (days) (aerobic)	DT50 (typical)	20	M4	Non-persistent
	DT50 (lab at 20oC)	-	-	-
	DT50 (field)	28	L3	Non-persistent
	DT90 (lab at 20oC)	-	-	-
	DT90 (field)	-	-	-
	Note	Best available data
Aqueous photolysis DT50 (days) at pH 7	Value	-	-	-
	Note	-
Aqueous hydrolysis DT50 (days) at 20oC and pH 7	Value	103	L3	Persistent
	Note	-
Water-sediment DT50 (days)		-	-	-
Water phase only DT50 (days)		-	-	-

Soil adsorption and mobility:

Property		Value	Source/Quality Score/Other Information	Interpretation
Linear	Kd	-	H3	Moderately mobile
	Koc	300
	Notes and range	Other sources: 2000 mL/g (DW3)
Freundlich	Kf	-	-	-
	Kfoc	-
	1/n	-
	Notes and range	-
pH sensitivity		-

ECOTOXICOLOGY
for promecarb

Property		Value	Source/Quality Score/Other Information	Interpretation
Bio-concentration factor	BCF	75	Q2 Estimated	Low potential
	CT50 (days)	Not available		-
Bioaccumulation potential		-	Calculated	Low
Mammals - Acute oral LD50 (mg kg-1)		> 23	L3 Mouse	High
Mammals - Short term dietary NOEL	(mg kg-1)	-	-	-
	(ppm diet)	-		-
Birds - Acute LD50 (mg kg-1)		78	V3 Phasianidae	High
Birds - Short term dietary (LC50/LD50)		-	-	-
Fish - Acute 96 hour LC50 (mg l-1)		0.31	L3 Oncorhynchus mykiss	Moderate
Fish - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1)		-	-	-
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1)		-	-	-
Aquatic plants - Acute 7 day EC50, biomass (mg l-1)		-	-	-
Algae - Acute 72 hour EC50, growth (mg l-1)		-	-	-
Algae - Chronic 96 hour NOEC, growth (mg l-1)		-	-	-
Honeybees	Contact acute 48 hour LD50 (μg bee-1)	-	-	-
	Oral acute 48 hour LD50 (μg bee-1)	-	-	-
	Unknown mode acute 48 hour LD50 (μg bee-1)	1.1	L3	Moderate
Earthworms - Acute 14 day LC50 (mg kg-1)		> 8.81	R4 Eisenia foetida	High
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1)		-	-	-
Other soil macro-organisms - e.g. Collembola	LR50 / EC50 / NOEC / % Effect	-	-	-
Other arthropod (1)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Other arthropod (2)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Soil micro-organisms		-	-	-
Mesocosm study data	NOEAEC mg l-1	-	-	-
	NOEAEC mg l-1	-	-	-

HUMAN HEALTH AND PROTECTION
for promecarb

General:

Property		Value	Source/Quality Score/Other Information	Interpretation
Mammals - Acute oral LD50 (mg kg-1)		> 23	L3 Mouse	High
Mammals - Dermal LD50 (mg kg-1 body weight)		450	L3 Rat	-
Mammals - Inhalation LC50 (mg l-1)		0.16	L3 Rat, 4 hr	-
Other Mammal toxicity endpoints		-		-
ADI - Acceptable Daily Intake (mg kg-1bw day-1)		-	-	-
ARfD - Acute Reference Dose (mg kg-1bw day-1)		-	-	-
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1)		-	-	-
Dermal penetration studies (%)		-	-	-
Dangerous Substances Directive 76/464		-	-	-
Exposure Limits		-	-	-
Exposure Routes	Public	-
	Occupational	-
Examples of European MRLs (mg kg-1)	Value	-
	Note	For the EU pesticides database click here
Drinking Water MAC (μg l-1)		-	-	-

Health issues:

Carcinogen	Mutagen	Endocrine disrupter	Reproduction / development effects	Cholinesterase inhibitor	Neurotoxicant	Respiratory tract irritant	Skin irritant	Eye irritant
	-	-	-
General human health issues		Toxic is swallowed

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:

Property		Value	Source/Quality Score/Other Information	Interpretation
General		Incompatible with alkaline substances
CLP classification 2013		-
EC Risk Classification		T - Toxic: R25 N - Dangerous for the environment: R50, R53
EC Safety Classification		S1/2, S24, S37, S45, S60, S61
WHO Classification		O	-	Obsolete substance
US EPA Classification (formulation)		No consensus across products or no products available	-	-
UN Number		-
Waste disposal & packaging		-

TRANSLATIONS
for promecarb

Language	Name
English	promecarb
French	promecarbe
German	Promecarb
Danish	promecarb
Italian	promecarb
Spanish	promecarb
Greek	promecarb
Slovenian	promekarb
Polish	promekarb
Swedish	-
Hungarian	-
Dutch	promecarb

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Record last updated: Tuesday 06 January 2015
Contact: aeru@herts.ac.uk