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GET ADDITIONAL DATA HERE!

propaquizafop (Ref: CGA 233380)
** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for propaquizafop

Description: A post-emergence herbicide used to control annual grass weeds and volunteer cereals in a range of crops

Example pests controlled: Wild oats; Sweet signal grass; Couch grass; Grabgrass; Goose grass; Common buffalo grass; Italian ryegrass

Example applications: Sugarbeet; Oilsed rape; Soybean; Sunflower; Vegetables; Fruit; Potatoes

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1991

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur UK/Estonia
Date inclusion expires 30/11/2021
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism Isomeric
Chemical formula C22H22ClN3O5
Canonical SMILES CC(C(=O)OCCON=C(C)C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl
Isomeric SMILES C[C@H](C(=O)OCCON=C(C)C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl
International Chemical Identifier key (InChIKey) FROBCXTULYFHEJ-OAHLLOKOSA-N
International Chemical Identifier (InChI) InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Aryloxyphenoxypropionate
Minimum active substance purity -
Known relevant impurities EU dossier - toluene <5 g/kg
Substance origin Synthetic
Mode of action Systemic, absorbed by foliage and roots and translocated. ACCase inhibitor.
CAS RN 111479-05-1
EC number -
CIPAC number 713
US EPA chemical code -
PubChem CID 16213016
Molecular mass (g mol-1) 443.88
PIN (Preferred Identification Name) -
IUPAC name 2-isopropylideneaminooxyethyl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenoxy]propionate
CAS name 2-[[(1-methylethylidene)amino]oxy]ethyl (2R)-2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoate
Other status information OSPAR soc
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) A
Herbicide Resistance Classification (WSSA) 1
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Alopecurus myosuroides
Brachiaria plantaginea
Eleusine indica
Physical state Off-white coloured powder
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • AgriGuard
  • Greencrop
  • Makhteshim-Agan
  • Standon
  • Teliton
Example products using this active
  • Falcon
  • Shogun
  • Zealot
  • Agil 100EC
  • Longhorn
UK LERAP status None
Formulation and application details Often supplied as emulsifiable concentrates that are mixed with water and used as a spray.


ENVIRONMENTAL FATE

for propaquizafop

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 0.63 A5 Low
Solubility - In organic solvents at 20oC (mg l-1) 500000 A5 - Acetone -
100000 C4 - Chloroform -
76000 A5 - Methanol -
500000 A5 - Toluene -
Melting point (oC) 66.3 A5 -
Boiling point (oC) Decomposes before boiling A3 -
Degradation point (oC) 260 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 6.03 X 1004 Calculated -
Log P 4.78 A5 High
Bulk density (g ml-1)/Specific gravity 0.96 B5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation between pH 4 and pH 9
Vapour pressure at 20oC (mPa) 4.39 X 10-07 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 9.20 X 10-08 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index - - -
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value - - -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - - -
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution: 235.0nm = 30500, 334.0nm = 5850; [Acidic solution: 235.0nm = 30000, 334.0nm = 5810; [Basic solution: 235.0nm = 29700, 334.0 nm = 5790; [No absorbance found between 400 and 750nm A5 -
Surface tension (mN m-1) 53.5-55.4 A5 at 20oC -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 2.1 A5 Non-persistent
DT50 (lab at 20oC) 1.3 A5 Non-persistent
DT50 (field) 85 A5 Moderately persistent
DT90 (lab at 20oC) 20 A4 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab study DT50 <3days, field studies DT50 range 15-215 days, DT90 range 2-56 days; Other field studies DT50 range 15-26 days for spring applications
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 32 A5 Stable
Note Data for seasonal average at 50 deg N. No difference between light and dark conditions.
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 32 A5 Moderately persistent
Note pH sensitive: DT50 10.5 days at pH 5, 12.9 hours at pH 9
Water-sediment DT50 (days) <1 A5 -
Water phase only DT50 (days) <1 A5 -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
quizalofop (Ref: CGA 287422) This metabolite may cause environmental pollution, click here for further information Soil   0.879   Major fraction, Relevant
hydroxy quizalofop (Ref: CGA 294972) This metabolite may cause environmental pollution, click here for further information Soil   0.326   Major fraction, Relevant
dihydroxy quinoxaline (Ref: CGA 294970) This metabolite may cause environmental pollution, click here for further information Soil   0.137   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
2-[4-(6-chloroquinoxalin-2-yloxy)phenol] quizalofop-phenol Plant - -
(R)-2-[4-(6-chloro-3-hydroxyquinoxalin-2-yloxy)phenoxy]propionic acid hydroxy-quizalofop-phenol Plant - -
6-chloroquinoxalin-2-ol
Note: Possible groundwater contaminant
hydroxyquinoxaline Plant; Soil (Aerobic) - -
6-chloroquinoxaline-2,3-diol dihydroxy-quinoxaline Plant; Soil (Aerobic); Water/sediment - -


ECOTOXICOLOGY

for propaquizafop

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 583 A5 Whole fish Threshold for concern
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) 6.25 B5 Rat High
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 2000 A5 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) > 827 mg kg bw-1 day-1 A5 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 0.19 A5 Cyprinus carpio Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.019 A5 Oncorhynchus mykiss Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 0.9 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.44 A5 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) > 1.4 A5 Lemna gibba Moderate
Non-target plants > 400 A5 Lettuce, OSR, Carrot, Oat
Vegetative vigour, ER50
as g/ha
-
> 400 A5 Lettuce, OSR, Carrot, Oat
Seedling emergence, ER50
as g/ha
-
Algae - Acute 72 hour EC50, growth (mg l-1) > 2.1 A5 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) > 2.1 Q2 Unknown species Low
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 200 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 20 A5 Moderate
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 500 A5 Eisenia foetida, corr Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 1.95 E4 Eisenia foetida Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 150 <
A5 Aphidius rhopalosiphi
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 200 A5 Typhlodromus pyri -
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 2.0 mg kg-1 soil, 28 days
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for propaquizafop

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 2.5 A5 Rat, 4 hr -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.015 A5 Mouse, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) None allocated A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.04 A5 Mouse, SF=100 -
Dermal penetration studies (%) 10 A3 default -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Acceptable for bystanders considering the proposed uses
Low risk for consumers
Occupational Acceptable for proposed uses - PPE/PPC advised
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; A5 Calc MAC=45.0 μg l-1 -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues No further information available

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 Health: H304, H319
Environment: H411
EC Risk Classification Click here to view information omn the EU risk phrases Carcinogen category 3: R40
Xn - Harmful: R43
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S24, S36, S37, S39, S60, S61
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number Usually 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for propaquizafop

Language Name
English propaquizafop
French propaquizafop
German Propaquizafop
Danish propaquizafop
Italian propaquizafop
Spanish propaquizafop
Greek -
Slovenian propakvizafop
Polish propakwizafop
Swedish propakizafop
Hungarian propaquizafop
Dutch -

Record last updated: Friday 14 September 2018
Contact: aeru@herts.ac.uk