Propoxur (Ref: OMS 33) |
![]() Last updated: 03/03/2020 |
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(Also known as: arprocarb; PHC; propotox; ENT 25671) |
SUMMARY |
Propoxur is a carbamate pesticide not approved for use in the EU. With a high aqueous solubilty, it has potential for being mobile in groundwaters although it is rarely reported. It is not highly volatile. In some instances it may persist in soil systems. It is highly toxic to humans if it is ingested but not other serious health issues have been identified. There are gaps in information relating to the toxicity of propoxur to biodiversity but based on information that is available it likely to be moderately to highly toxic. . |
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A insecticide and acaricide active against a wide range of pests especially those that cause damage via sucking and chewing. Also used for flea control on domestic pets. | |
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Cockroaches; Flies; Mosquitoes; Fleas; Ticks; Aphids; Leaf hoppers | |
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Ornamentals; Lawns & turf; Glasshouse crops including tomatoes & cucumbers | |
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Current | |
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1959; first registered in the US in 1963. |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Australia, USA |
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Chemical structure |
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C₁₁H₁₅NO₃ | |
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CC(C)OC1=CC=CC=C1OC(=O)NC | |
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No data | |
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ISRUGXGCCGIOQO-UHFFFAOYSA-N | |
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InChI=1S/C11H15NO3/c1-8(2)14-9-6-4-5-7-10(9)15-11(13)12-3/h4-8H,1-3H3,(H,12,13) | |
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Yes |
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Common Name | Relationship | Link |
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propoxur | - | ![]() |
General status |
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Insecticide, Acaricide, Veterinary substance | |
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Carbamate | |
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- | |
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Synthetic | |
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Non-systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor. | |
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114-26-1 | |
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204-043-8 | |
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80 | |
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047802 | |
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4944 | |
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209.24 | |
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- | |
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2-isopropoxyphenyl methylcarbamate | |
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2-(1-methylethoxy)phenyl methylcarbamate | |
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Marine Pollutant | |
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- | |
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Not applicable | |
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Not applicable | |
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1A | |
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Not applicable | |
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Aedes aegypti, Amblyseius potentillae, Anopheles albimanus, Anopheles atroparvus, Anopheles funestus, many others | |
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White crystalline solid |
Formulations |
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Often supplied as emulsifiable concentrates, granules, dusts or wettable powders |
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1800 | H4 H = The US ARS pesticide properties database (click here ) 4 = Verified data |
High | ||||||||
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200000 | L3 L = Pesticide manuals and hard copy reference books / other sources Isopropanol3 = Unverified data of known source |
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94000 | L3 L = Pesticide manuals and hard copy reference books / other sources Toluene3 = Unverified data of known source |
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1300 | L3 L = Pesticide manuals and hard copy reference books / other sources Hexane3 = Unverified data of known source |
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90 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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Decomposes on distillation | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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1.38 X 1000 | Calculated | - | |||||||
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0.14 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
Low | ||||||||
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1.18 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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1.3 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
Low volatility | ||||||||
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1.50 X 10-04 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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79 | K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data |
Moderately persistent | |||||||
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30 | Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source |
Moderately persistent | ||||||||
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28 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-persistent | ||||||||
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Best available data | ||||||||||
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0.65 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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Leaves of ornamentals grown undercover, n=1 | ||||||||||
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0.4 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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Beans, leaves, n=1 | ||||||||||
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0.01 | K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data |
Fast | |||||||
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180 | K3 K = Research datasets, e.g. Pandora, Demetra 3 = Unverified data of known source |
Persistent | |||||||
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2 | K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data |
Fast | ||||||||
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Soil adsorption and mobility |
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- | G3 G = Extension Toxicology network database EXTOXNET (click here ) 3 = Unverified data of known source |
Mobile | |||||||
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30 | ||||||||||
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Fate indices |
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3.65 | Calculated | High leachability | ||||||||||||||||||||||||||
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5.62 X 10-01 | Calculated | - | |||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Mobile | Calculated | - |
Other known metabolites |
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2-(1-methylethoxy)phenol | - | Soil (Photolysis) | - | - | |||||
dimethyl propoxus | - | Plant | 0.27-0.36 | - |
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Low risk | R3 R = Peer reviewed scientific publications Rapid aquatic degradation3 = Unverified data of known source |
Low risk | |||||||
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Not available | - | |||||||||
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~ 50 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
High | ||||||||
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- | L2 L = Pesticide manuals and hard copy reference books / other sources Rat 2 year2 = Unverified data of unknown source |
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200 | - | |||||||||
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> 25.9 | G4 G = Extension Toxicology network database EXTOXNET (click here ) Colinus virginianus4 = Verified data |
High | ||||||||
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6.2 | E3 E = Manufacturers safety data sheets Lepomis macrochirus3 = Unverified data of known source |
Moderate | ||||||||
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0.15 | E3 E = Manufacturers safety data sheets Daphnia magna3 = Unverified data of known source |
Moderate | ||||||||
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0.016 | P3 P = Other governments and regulators Daphnia magna survival 42 day3 = Unverified data of known source |
Moderate | ||||||||
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38.1 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Chironomus riparius 1 day3 = Unverified data of known source |
Moderate | ||||||||
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< 0.112 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Apis mellifera 24hr3 = Unverified data of known source |
High | |||||||
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> 1.35 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Moderate | ||||||||
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> 1.6 | R4 R = Peer reviewed scientific publications Bombus terrestris4 = Verified data |
Moderate | ||||||||
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Harmful | AA2 AA = IOBC Database on classification of side effects to beneficial organisms, 2005 Chrysoperla carnea2 = Unverified data of unknown source |
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General |
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High (class III) | - | - | ||||||||
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~ 50 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
High | ||||||||
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5000 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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> 0.50 | E3 E = Manufacturers safety data sheets Rat3 = Unverified data of known source |
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Intraperitoneal LD₅₀ = 30 mg kg⁻¹ | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
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Intramuscular LD₅₀ = 53 mg kg⁻¹ | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
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0.02 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) JMPR 19893 = Unverified data of known source |
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Health issues |
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Toxic USEPA - probable human carcinogen Endocrine issues - Weak estrogenic effect |
Handling issues |
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No information available | |||
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Health: H301 Environment: H400, H410 |
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T - Toxic: R25 N - Dangerous for the environment: R50, R53 |
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S2, S37, S45, S60, S61 | |||
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II (Moderately hazardous) | |||
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2757 | |||
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propoxur | ||
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propoxur | ||
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Propoxur | ||
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propoxur | ||
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propoxur | ||
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propoxur | ||
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propoxur | ||
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propoksur | ||
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propoxur |
Record last updated: | 03/03/2020 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |