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pyrazophos (Ref: HOE 2873)
** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for pyrazophos

Description: A fungicide used to control Erysiphe, Helminthosporium and Rhynchospium in cereals

Introduction: circa 1970

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Netherlands
Date inclusion expires Not applicable

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Fungicide
Substance group Phosphorothiolate
Substance origin Synthetic
Mode of action Systemic with protective and curative action
CAS RN 13457-18-6
EC number 236-656-1
CIPAC number 350
US EPA chemical code 447500
Chiral molecule No
Chemical formula C14H20N3O5PS
SMILES S=P(OCC)(OCC)Oc1nn2cc(c(nc2c1)C)C(=O)OCC
International Chemical Identifier (InChI) InChI=1/C14H20N3O5PS/c1-5-19-14(18)11-9-17-12(15-10(11)4)8-13(16-17)22-23(24,20-6-2)21-7-3/h8-9H,5-7H2,1-4H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 373.36
PIN (Preferred Identification Name) -
IUPAC name ethyl 2-diethoxyphosphinothioyloxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS name ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
Other status information Severe Marine Pollutant
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 6
Physical state Colourless to olive brown crystals
Related substances & organisms

Formulations:
Property Value
Example manufacturers of products using this active
  • Bayer CropScience
Example products using this active
  • Furesan
  • Masolon
  • Siganex
  • Sigma
UK LERAP status No UK approval for use or outside scope
Formulation and application details Usually supplied as an emulsifiable concentrate.


ENVIRONMENTAL FATE

for pyrazophos

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 4.2 K4 Low
Solubility - In organic solvents at 20oC (mg l-1) 400000 L3 - Acetone -
400000 L3 - Toluene -
400000 L3 - Ethyl acetate -
16600 L3 - Hexane -
Melting point (oC) 51.5 L3 -
Boiling point (oC) Decomposes before boiling L3 -
Degradation point (oC) 160 L3 -
Flashpoint (oC) 34 L3 - (closed cup) -
Octanol-water partition coefficient at pH 7, 20oC P 6.31 X 1003 Calculated -
Log P 3.8 L3 High
Bulk density (g ml-1)/Specific gravity 1.35 L3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 0.22 L3 Non-volatile
Henry's law constant at 25oC (Pa m3 mol-1) 2.58 X 10-04 L3 Non-volatile
Henry's law constant at 20oC (dimensionless) 3.65 X 10-06 Q2 Moderately volatile
GUS leaching potential index 1.89 Calculated Transition state
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 6.57 X 10-02 Calculated -
Note -
Potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 39 W4 Moderately persistent
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Best available data
Aqueous photolysis DT50 (days) at pH 7 Value Stable Q2 Stable
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 41 Q2 Moderately persistent
Note -
Water-sediment DT50 (days) 10 K4 Fast
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - W3 Slightly mobile
Koc 646
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for pyrazophos

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF 360 P4 Threshold for concern
CT50 (days) Not available -
Bioaccumulation potential - Calculated Moderate
Mammals - Acute oral LD50 (mg kg-1) 151 L3 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 5 -
Birds - Acute LD50 (mg kg-1) 118 L3 Phasianidae Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.48 L3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.00036 L3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.00018 L3 Daphnia magna -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) 65.5 L3 Scenedemus subspicatus Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (μg bee-1) > 0.25 L3 Contact High
Earthworms - Acute 14 day LC50 (mg kg-1) 1000 L3 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for pyrazophos

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) 151 L3 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 1.22 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.004 JMPR 1993 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
Examples of European MRLs (mg kg-1) Value Vegetables, fruit and cereal grains: 0.05
Note Current May 2007.
For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

-

-

-

General human health issues Moderately toxic
Harmful

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General IMDG Transport Code is usually 6.1
CLP classification 2013 -
EC Risk Classification Xn - Harmful: R20/22
N - Dangerous for the environment: R50, R53
EC Safety Classification S2, S36/37, S46, S60, S61
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) II - Warning - Moderately toxic
UN Number 2784 for active, products usually 2783
Waste disposal & packaging Packaging Group III (minor danger)


TRANSLATIONS

for pyrazophos

Language Name
English pyrazophos
French pyrazophos
German Pyrazophos
Danish pyrazophos
Italian pirazofos
Spanish pirasofos
Greek pyrazophos
Slovenian pirazofos
Polish pyrazofos
Swedish -
Hungarian -
Dutch pyrazofos

Record last updated: Monday 29 July 2013
Contact: aeru@herts.ac.uk