Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides

pyrazophos (Ref: HOE 2873)
** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for pyrazophos

Description: A fungicide used to control Erysiphe, Helminthosporium and Rhynchospium spp. in cereals and otehr crops

Example pests controlled: Powdery mildew

Example applications: Cereals; Vegetables including curcubits, brassicas, egg plants; Hops; Some fruit including apples, apricots, citrus, melon; Ornamentals; Cucumber; Tobacco

Availability status: Unknown

Introduction & key dates: circa 1970

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Netherlands
Date inclusion expires Not applicable

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Fungicide
Substance group Phosphorothiolate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Systemic with protective and curative action. Phospholipid biosynthesis inhibitor.
CAS RN 13457-18-6
EC number 236-656-1
CIPAC number 350
US EPA chemical code 447500
Chiral molecule No
Chemical formula C14H20N3O5PS
SMILES S=P(OCC)(OCC)Oc1nn2cc(c(nc2c1)C)C(=O)OCC
International Chemical Identifier key (InChIKey) JOOMJVFZQRQWKR-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C14H20N3O5PS/c1-5-19-14(18)11-9-17-12(15-10(11)4)8-13(16-17)22-23(24,20-6-2)21-7-3/h8-9H,5-7H2,1-4H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 373.36
PIN (Preferred Identification Name) -
IUPAC name ethyl 2-diethoxyphosphinothioyloxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS name ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
Other status information Severe Marine Pollutant; Chemical subject to PIC regulations; PAN listed Highly Hazardous Chemical
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 6
Examples of recorded resistance Liriomyza trifolii
Physical state Colourless to olive brown crystals
Related substances & organisms

Formulations:
Property Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • Hoechst
Example products using this active
  • Furesan
  • Masolon
  • Siganex
  • Sigma
  • Afugan
  • Curamil
UK LERAP status No UK approval for use or outside scope
Formulation and application details Usually supplied as an emulsifiable concentrate or wettable powder.


ENVIRONMENTAL FATE

for pyrazophos

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 4.2 K4 Low
Solubility - In organic solvents at 20oC (mg l-1) 400000 L3 - Acetone -
400000 L3 - Toluene -
400000 L3 - Ethyl acetate -
16600 L3 - Hexane -
Melting point (oC) 51.5 L3 -
Boiling point (oC) Decomposes before boiling L3 -
Degradation point (oC) 160 L3 -
Flashpoint (oC) 34 L3 - (closed cup) -
Octanol-water partition coefficient at pH 7, 20oC P 6.31 X 1003 Calculated -
Log P 3.8 L3 High
Bulk density (g ml-1)/Specific gravity 1.35 L3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 0.22 L3 Volatile
Henry's law constant at 25oC (Pa m3 mol-1) 2.58 X 10-04 L3 Non-volatile
Henry's law constant at 20oC (dimensionless) 3.65 X 10-06 Q2 Moderately volatile
GUS leaching potential index 1.89 Calculated Transition state
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 6.57 X 10-02 Calculated -
Note -
Potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 39 W4 Moderately persistent
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Best available data
Plant matrix DT50 (days) Value 8.2 R4 -
Note DT50 range 2.3 - 25.0 days, 4 crops/plants, various matrices
Aqueous photolysis DT50 (days) at pH 7 Value Stable Q2 Stable
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 41 Q2 Moderately persistent
Note -
Water-sediment DT50 (days) 10 K4 Fast
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - W3 Slightly mobile
Koc 646
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for pyrazophos

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF (l kg-1) 360 P4 Threshold for concern
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 151 L3 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 5 -
Birds - Acute LD50 (mg kg-1) 118 L3 Phasianidae Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.48 L3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.00036 L3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.00018 L3 Daphnia magna High
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 65.5 L3 Scenedemus subspicatus Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 0.25 L3 High
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) 1000 L3 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for pyrazophos

General:
Property Value Source/Quality Score/Other Information Interpretation
Threshold of Toxicological Concern (Cramer Class) High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 151 L3 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 1.22 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.004 JMPR 1993 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

General human health issues Moderately toxic
Harmful

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H302, H332
Environment: H400, H410
EC Risk Classification Xn - Harmful: R20/22
N - Dangerous for the environment: R50, R53
EC Safety Classification S2, S36/37, S46, S60, S61
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) II - Warning - Moderately toxic
UN Number 2784 for active, products usually 2783
Waste disposal & packaging Packaging Group III (minor danger)


TRANSLATIONS

for pyrazophos

Language Name
English pyrazophos
French pyrazophos
German Pyrazophos
Danish pyrazophos
Italian pirazofos
Spanish pirasofos
Greek pyrazophos
Slovenian pirazofos
Polish pyrazofos
Swedish -
Hungarian -
Dutch pyrazofos

Record last updated: Sunday 14 August 2016
Contact: aeru@herts.ac.uk