(Also known as: synthrin; OMS 1800; FMC 17370; SBP-1382)
SUMMARY
Data alerts
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate Moderate alert: Potential for particle bound transport: Medium
Warning: Significant data are missing
Ecotoxicity High alert: Fish acute ecotoxicity: High; Fish chronic ecotoxicity: High; Daphnia acute ecotoxicity: High; Bees acute contact ecotoxicity: High; Bees acute oral ecotoxicity: High
Human health High alert: Endocrine distrupter; Reproduction/development effects; Neurotoxicant
GENERAL INFORMATION
Description
A broad spectrum insecticide effective against a wide range of crawling and flying pests
Example pests controlled
Mosquitoes; Fleas; House flies; Blackflies; Gnats; Fruit flies; Wasps; Hornets; Coachroaches; Crickets; Ants; Carpet beetles
Example applications
Residences and other buildings; Landscapes; Muschroom houses; Industrial sites; Store produce; Fabric protection
Efficacy & activity
-
Availability status
Current
Introduction & key dates
1967, first produced; 1969, first marketed in Japan
UK regulatory status
UK COPR regulatory status
Not approved
Date COPR inclusion expires
Expired
UK LERAP status
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
EC Regulation 1107/2009 status
Not approved
Dossier rapporteur/co-rapporteur
Not applicable
Date EC 1107/2009 inclusion expires
Expired
EU Candidate for substitution (CfS)
-
Listed in EU database
Yes
Approved for use (✓) under EC 1107/2009 in the following EU Member States
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
Additional information
Also used in
USA
Chemical structure
Isomerism
A chiral molecule. The technical material is an isomeric mixture of four optical isomers: [1R, trans]-, [1R, cis]-, [1S, trans]- and [1S, cis]- in roughly the ration 4:1:4:1.
Example manufacturers & suppliers of products using this active now or historically
Bayer
Prentiss Incorporated
Sumitomo Chemical Co. Ltd.
Example products using this active
Benzofuroline
Chrysron
Derringer
Scourge
Formulation and application details
Usually formulated as an emulsifiable concentrate, emulsion or ULV
ENVIRONMENTAL FATE
Property
Value
Source; quality score; and other information
Interpretation
Solubility - In water at 20 °C (mg l⁻¹)
0.01
G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data
Low
Solubility - In organic solvents at 20 °C (mg l⁻¹)
-
-
-
Melting point (°C)
56.5
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Boiling point (°C)
Decomposes before boiling
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Degradation point (°C)
180
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Flashpoint (°C)
129
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Octanol-water partition coefficient at pH 7, 20 °C
P
2.69 X 1005
Calculated
-
Log P
5.43
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
Fat solubility of residues
Solubility
Soluble
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes
-
Data type
Observed in metabolism and farm animal feeding studies
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes
-
Density (g ml⁻¹)
0.96
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Dissociation constant pKa) at 25 °C
-
-
-
-
Vapour pressure at 20 °C (mPa)
0.0015
G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data
Low volatility
Henry's law constant at 25 °C (Pa m³ mol⁻¹)
8.93 X 10-02
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
Maximum UV-vis absorption L mol⁻¹ cm⁻¹
-
-
-
Surface tension (mN m⁻¹)
-
-
-
Degradation
Property
Value
Source; quality score; and other information
Interpretation
General biodegradability
-
Soil degradation (days) (aerobic)
DT₅₀ (typical)
30
G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data
G3 G = Extension Toxicology network database EXTOXNET (click here ) 3 = Unverified data of known source
Non-mobile
Koc
100000
Notes and range
-
Freundlich
Kf
-
-
-
Kfoc
-
1/n
-
Notes and range
-
pH sensitivity
-
Fate indices
Property
Value
Source; quality score; and other information
Interpretation
GUS leaching potential index
-1.48
Calculated
Low leachability
SCI-GROW groundwater index (μg l⁻¹) for a 1 kg ha⁻¹ or 1 l ha⁻¹ application rate
Value
5.35 X 10-03
Calculated
-
Note
Estimated concentrations of chemicals with Koc values greater than 9995 ml g⁻¹ are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index
Medium
Calculated
-
Potential for loss via drain flow
Non-mobile
Calculated
-
Bio-concentration factor
BCF (l kg⁻¹)
68
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
Aquatic plants - Acute 7 day EC₅₀, biomass (mg l⁻¹)
-
-
-
Algae - Acute 72 hour EC₅₀, growth (mg l⁻¹)
1.6
K3 K = Research datasets, e.g. Pandora, Demetra 3 = Unverified data of known source
Unknown species
Moderate
Algae - Chronic 96 hour NOEC, growth (mg l⁻¹)
-
-
-
Mesocosm study data
NOEAEC mg l⁻¹
-
-
-
NOEAEC mg l⁻¹
-
-
-
HUMAN HEALTH AND PROTECTION
General
Property
Value
Source; quality score; and other information
Interpretation
Threshold of Toxicological Concern (Cramer Class)
High (class III)
-
-
Mammals - Acute oral LD₅₀ (mg kg⁻¹)
> 2500
G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data
Rat
Low
Mammals - Dermal LD₅₀ (mg kg⁻¹ body weight)
3000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
Mammals - Inhalation LC₅₀ (mg l⁻¹)
9.49
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
Other Mammal toxicity endpoints
-
-
-
ADI - Acceptable Daily Intake (mg kg⁻¹ bw day⁻¹)
0.125
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
ARfD - Acute Reference Dose (mg kg⁻¹ bw day⁻¹)
0.03
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242
Environmental fate
Warning:
Ecotoxicity
