The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate Moderate alert: Moderately persistent; GUS: Transition state; Drainflow: Moderately mobile; Potential for particle bound transport: Medium
A soil-acting herbicide with used to control most germinating annual grasses and broad-leaved weeds. Has also been used to control algae in ponds and fish hatcheries.
Selective, systemic, absorbed through roots and foliage and translocated. Inhibits photosynthesis (photosystem II).
CAS RN
122-34-9
EC number
204-535-2
CIPAC number
22
US EPA chemical code
080807
PubChem CID
5216
CLP index number
612-088-00-3
Molecular mass
201.66
PIN (Preferred Identification Name)
6-chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine
IUPAC name
6-chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine
CAS name
6-chloro-N,N'-diethyl-1,3,5-triazine-2,4-diamine
Other status information
WFD priority substance; Potential groundwater and surface water contaminant; Chemical subject to PIC regulations
Relevant Environmental Water Quality Standards
EU Directive 2008/105/EC EQS surface waters: annual average 1.0 µg l⁻¹; max measured 4.0 µg l⁻¹ UK stutory standard for the protection of aquatic life: freshwater and salt water annual average 2 µg l⁻¹
Herbicide Resistance Classification (HRAC)
C1
Herbicide Resistance Classification (WSSA)
5
Insecticide Resistance Classification (IRAC)
Not applicable
Fungicide Resistance Classification (FRAC)
Not applicable
Examples of recorded resistance
Amaranthus albus, Amaranthus blitoides
Physical state
Colourless to white solid
Formulations
Property
Value
Example manufacturers & suppliers of products using this active now or historically
Loveland Chemicals
Makhteshim Agan
Syngenta
Example products using this active
Sanazine
Simanex
Amizina
Eagrow
Derby
Formulation and application details
Available in a range of formulations including wettable powders, water dispersible granules, liquids and granules.
ENVIRONMENTAL FATE
Property
Value
Source; quality score; and other information
Interpretation
Solubility - In water at 20 °C (mg l⁻¹)
5
B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes
Low
Solubility - In organic solvents at 20 °C (mg l⁻¹)
570
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Ethanol
-
1500
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
130
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Toluene
-
3.1
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
n-Hexane
-
Melting point (°C)
Decomposes before melting
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Boiling point (°C)
Decomposes before boiling
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Degradation point (°C)
226
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Flashpoint (°C)
-
-
-
Octanol-water partition coefficient at pH 7, 20 °C
P
2.00 X 1002
Calculated
-
Log P
2.3
B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes
Low
Fat solubility of residues
Solubility
-
-
-
Data type
-
-
-
Density (g ml⁻¹)
1.3
B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes
-
Dissociation constant pKa) at 25 °C
1.62
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Very weak base
Vapour pressure at 20 °C (mPa)
0.00081
B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes
Low volatility
Henry's law constant at 25 °C (Pa m³ mol⁻¹)
5.60 X 10-05
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
Maximum UV-vis absorption L mol⁻¹ cm⁻¹
-
-
-
Surface tension (mN m⁻¹)
-
-
-
Degradation
Property
Value
Source; quality score; and other information
Interpretation
General biodegradability
-
Soil degradation (days) (aerobic)
DT₅₀ (typical)
60
DW4 DW = Don Wauchope personal database for Pka data: Wauchope, R. D. and Edwards, J. Dissociation constants for pesticide active ingredients: a database and comparison with predicted values. MS in preparation 4 = Verified data
Moderately persistent
DT₅₀ (lab at 20 °C)
-
-
-
DT₅₀ (field)
90
B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 4 = Verified data
Moderately persistent
DT₉₀ (lab at 20 °C)
-
-
-
DT₉₀ (field)
-
-
-
DT₅₀ modelling endpoint
-
-
-
Note
Other sources: DT₅₀ 27-102 days (R3), 91 days at 25 °C (R4)
Dissipation rate RL₅₀ on plant matrix
Value
-
-
-
Note
-
Dissipation rate RL₅₀ on and in plant matrix
Value
-
-
-
Note
-
Aqueous photolysis DT₅₀ (days) at pH 7
Value
1.9
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Moderately fast
Note
Unstable in UV light
Aqueous hydrolysis DT₅₀ (days) at 20 °C and pH 7
Value
96
B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 4 = Verified data
Moderately persistent
Note
Stable under normal environmental conditions, hydrolysis does occur in strong acid and alkai solutions
Water-sediment DT₅₀ (days)
33
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
Moderately fast
Water phase only DT₅₀ (days)
46
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Stable
Soil adsorption and mobility
Property
Value
Source; quality score; and other information
Interpretation
Linear
Kd
-
G3 G = Extension Toxicology network database EXTOXNET (click here ) 3 = Unverified data of known source
Moderately mobile
Koc
130
Notes and range
Other sources: Log Koc 2.14 at 25 °C (R3), 2.11 (R3)
Freundlich
Kf
15.88
R4 R = Peer reviewed scientific publications 4 = Verified data
Slightly mobile
Kfoc
750
1/n
0.76
Notes and range
Kf range 4.59-20.6 mL g⁻¹, Kfoc range 124-1585 mL g⁻¹, 1/n range 0.33-0.89, Soils=3
pH sensitivity
-
Fate indices
Property
Value
Source; quality score; and other information
Interpretation
GUS leaching potential index
2.20
Calculated
Transition state
SCI-GROW groundwater index (μg l⁻¹) for a 1 kg ha⁻¹ or 1 l ha⁻¹ application rate
B4 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 4 = Verified data
UK ACP 1999
-
Dermal penetration studies (%)
-
-
-
Dangerous Substances Directive 76/464
List II
-
-
Exposure Routes
Public
-
Occupational
-
MRLs
European
EU MRL pesticide database 
Great Britain
GB MRL Register 
Notes
-
Drinking Water Standards
Non-statutory WHO drinking water guideline 0.002 mg l⁻¹
B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) 5 = Verified data used for regulatory purposes
UK EA QS database 2018
-
Drinking Water MAC (μg l⁻¹)
-
-
-
Mammalian dose elimination route and rate
-
-
-
Health issues
Specific human health issues
Carcinogen
Genotoxic
Endocrine disruptor
?Possibly, status not identified
A3 A = Chromosome aberration (EFSA database) 3 = Negative
;
B3 B = DNA damage/repair (EFSA database) 3 = Negative
;
C3 C = Gene mutation (EFSA database) 3 = Negative
;
D0 D = Genome mutation (EFSA database) 0 = No data
;
E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
✓Yes, known to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
XNo, known not to cause a problem
?Possibly, status not identified
No data found
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
General human health issues
May cause dermatitis May cause tremor, convulsions, paralysis, cyanosis, slowed respiration and diarrhoea Endocrine issues - Induction of aromatase activity, increase of estrogen production
Handling issues
Property
Value and interpretation
General
Prevent generation of dust IMDG Transport Code is usually 9 Not expected to autoignite; Not highly flammable
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242