| tetradifon (Ref: ENT 23737) |
 |
Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
GENERAL INFORMATION 
for tetradifon
Description: An acaricide for use in horticultural crops to control a wide range of phytophagous mites
Example pests controlled: Citrus spider mite; Red spider mite; Flat mites; yellow mite
Example applications: Apples; Pears; Peaches; Citrus; Ornamentals; Cotton; Tea
Availability status: Current
Introduction & key dates: circa 1955
EC Regulation 1107/2009 (repealing 91/414):
| Status | Not approved |
| Dossier rapporteur/co-rapporteur | Not applicable |
| Date inclusion expires | Expired |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
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Also used in: Australia
General status:
| Pesticide type | Acaricide, Insecticide | |
| Substance group | Bridged diphenyl | |
| Minimum active substance purity | - | |
| Known relevant impurities | - | |
| Substance origin | Synthetic | |
| Mode of action | Non-systemic with larvicidal and ovicidal activity. Acts by inhibiting oxidative phosphorylation. | |
| CAS RN | 116-29-0 | |
| EC number | 204-134-2 | |
| CIPAC number | 113 | |
| US EPA chemical code | 079202 | |
| Chiral molecule | No | |
| Chemical formula | C12H6Cl4O2S | |
| SMILES | Clc1cc(c(Cl)cc1Cl)S(=O)(=O)c2ccc(Cl)cc2 | |
| International Chemical Identifier key (InChIKey) | MLGCXEBRWGEOQX-UHFFFAOYSA-N | |
| International Chemical Identifier (InChI) | InChI=1S/C12H6Cl4O2S/c13-7-1-3-8(4-2-7)19(17,18)12-6-10(15)9(14)5-11(12)16/h1-6H | |
| Structure diagram/image available? | Yes | |
| Molecular mass (g mol-1) | 356.06 | |
| PIN (Preferred Identification Name) | 1,2,4-trichloro-5-(4-chlorobenzene-1-sulfonyl)benzene | |
| IUPAC name | 4-chlorophenyl 2,4,5-trichlorophenyl sulfone | |
| CAS name | 1,2,4-trichloro-5-[(4-chlorophenyl)sulfonyl]benzene | |
| Other status information | OSPAR soc | |
| Herbicide Resistance Classification (HRAC) | Not applicable | |
| Herbicide Resistance Classification (WSSA) | Not applicable | |
| Insecticide Resistance Classification (IRAC) | 12C | |
| Fungicide Resistance Classification (FRAC) | Not applicable | |
| Examples of recorded resistance | Panonychus citri Panonychus ulmi Tetranychus mcdanieli Tetranychus urticae |
|
| Physical state | Colourless crystals | |
| Related substances & organisms | ||
Formulations:
| Property |
Value | |||
| Example manufacturers & suppliers of products using this active now or historically |
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| Example products using this active |
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| UK LERAP status | No UK approval for use or outside scope | |||
| Formulation and application details | Available in a variety of formulations including emulsifiable concentrates, wettable powders and smoke generators. | |||
ENVIRONMENTAL FATE
for tetradifon
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | 0.078 | L3 | Low | |
| Solubility - In organic solvents at 20oC (mg l-1) | 82000 | C4 - Acetone | - | |
| 255000 | C4 - Chloroform | - | ||
| 10000 | C4 - Methanol | - | ||
| 115000 | C4 - Xylene | - | ||
| Melting point (oC) | 146 | L3 | - | |
| Boiling point (oC) | - | - | - | |
| Degradation point (oC) | - | - | - | |
| Flashpoint (oC) | - | - | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | 4.07 X 1004 | Calculated | - |
| Log P | 4.61 | L3 | High | |
| Bulk density (g ml-1)/Specific gravity | 1.52 | L3 | - | |
| Dissociation constant (pKa) at 25oC | - | - | - | |
| Note: | ||||
| Vapour pressure at 25oC (mPa) | 3.20 X 10-05 | C4 | Intermediate state | |
| Henry's law constant at 25oC (Pa m3 mol-1) | 1.46 X 10-04 | L3 | Non-volatile | |
| Henry's law constant at 20oC (dimensionless) | 6.19 X 10-08 | Q2 | Non-volatile | |
GUS leaching potential index  |
4.10 | Calculated | High leachability | |
| SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | 1.44 X 10+00 | Calculated | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | Medium | |
| Maximum UV-vis absorption L mol-1 cm-1 | - | - | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Soil degradation (days) (aerobic) | DT50 (typical) | 112 | C4 | Persistent |
| DT50 (lab at 20oC) | 112 | C4 | Persistent | |
| DT50 (field) | - | - | - | |
| DT90 (lab at 20oC) | - | - | - | |
| DT90 (field) | - | - | - | |
| Note: | - | |||
| Plant matrix DT50 (days) | Value | 6.1 | R4 | - |
| Note | DT50 range 5.1 - 7.0 days, 2 crops/plants, fruit matrices | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | - | - | - |
| Note | - | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | Stable | C2 | Very persistent |
| Note | - | |||
| Water-sediment DT50 (days) | - | - | - | |
| Water phase only DT50 (days) | - | - | - | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | - | W3 | Moderately mobile |
| Koc | 100 | |||
| Notes and range | - | |||
| Freundlich | Kf | - | - | - |
| Kfoc | - | |||
| 1/n | - | |||
| Notes and range | - | |||
| pH sensitivity | - | |||
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF (l kg-1) | 190 | P4 (Other literature Log BCF range 1.7-2.0 (R3)) | Threshold for concern |
| CT50 (days) | Not available | - | ||
| Mammals - Acute oral LD50 (mg kg-1) | > 14700 | L3 Rat | Low | |
| Mammals - Short term dietary NOEL | (mg kg-1) | - | L2 Rat, 2 year | - |
| (ppm diet) | 200 | - | ||
| Birds - Acute LD50 (mg kg-1) | > 5000 | L3 Anas platyrhynchos | Low | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | > 880 | L3 Lepomis macrochirus | Low | |
| Fish - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | > 2 | L3 Daphnia magna | Moderate | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Non-target plants | - | - | - | |
| - | - | - | ||
| Algae - Acute 72 hour EC50, growth (mg l-1) | > 100 | L3 Raphidocelis subcapitata | Low | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | - | - | - | |
| Honeybees | Contact acute 48 hour LD50 (μg bee-1) | > 11 | C4 | Moderate |
| Oral acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Unknown mode acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Earthworms - Acute 14 day LC50 (mg kg-1) | > 5000 | L3 | Low | |
| Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms - e.g. Collembola | LR50 / EC50 / NOEC / % Effect | - | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | Harmless | Dose: 96 g ha-1 AA3 Typhlodromus pyri |
- | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | Harmless | Dose: 96 g ha-1 AA3 Chrysoperla carnea |
- | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
HUMAN HEALTH AND PROTECTION
for tetradifon
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Threshold of Toxicological Concern (Cramer Class) |
High (class III) | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | > 14700 | L3 Rat | Low | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | > 10000 | L3 Rabbit | - | |
| Mammals - Inhalation LC50 (mg l-1) | 3.0 | L3 Rat, 4 hr | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | - | - | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | - | - | - | |
| Exposure Limits | - | - | - | |
| Exposure Routes | Public | - | ||
| Occupational | May be absorbed into the body by inhalation of dust | |||
| European MRLs | Click here for the EU MRL pesticide database | |||
| Drinking Water MAC (μg l-1) | - | - | - | |
Health issues:
| Carcinogen | Mutagen | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
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| Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
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| General human health issues | Possible liver and kidney toxicant | |||||||
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found
Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| General |
Prevent generation of dust Flammable Tackle fires using a water spray or dry chemicals |
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| CLP classification 2013 | None allocated at this time | |||
| EC Risk Classification |
Xn- Harmful: R22 H - Handling risks: R10 |
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| EC Safety Classification |
- | |||
| WHO Classification | U | - | Unlikely to present an acute hazard | |
| US EPA Classification (formulation) | III | - | Caution - Slightly toxic | |
| UN Number | 1993 | |||
| Waste disposal & packaging |
Dispose of as chemical waste of low toxicity | |||
| Language | Name |
| English | tetradifon |
| French | tetradifon |
| German | Tetradifon |
| Danish | tetradifon |
| Italian | tetradifon |
| Spanish | tetradifon |
| Greek | - |
| Slovenian | tetradifon |
| Polish | tereadifon |
| Swedish | tetradifon |
| Hungarian | - |
| Dutch | - |
Record last updated: Sunday 14 August 2016
Contact: aeru@herts.ac.uk