| tridemorph (Ref: BAS 2205-F) |
 |
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GENERAL INFORMATION 
for tridemorph
Description: A fungicide used to control the fungus Erysiphe graminis in cereals and a range of other diseases
Example pests controlled: Powdery mildew; Rust; Leaf blotch; Eyespot
Example applications: Cereals; Bananas; Tea; Vegetables; Ornamentals
Availability status: Current
Introduction & key dates: 1969, Germany
EC Regulation 1107/2009 (repealing 91/414):
| Status | Not approved |
| Dossier rapporteur/co-rapporteur | Not applicable |
| Date inclusion expires | Expired |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
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Also used in: Australia
General status:
| Pesticide type | Fungicide | |||
| Substance group | Morpholine | |||
| Minimum active substance purity | - | |||
| Known relevant impurities | - | |||
| Substance origin | Synthetic | |||
| Mode of action | Systemic with eradicant action, absorbed by leaves and shoots, some protectant properties. Disrupts membrane function. | |||
| CAS RN | 81412-43-3 | |||
| Alternative/old CAS RN | 24602-86-6 | |||
| EC number | 246-347-3 | |||
| CIPAC number | 324 | |||
| US EPA chemical code | 121401 | |||
| Chiral molecule | Chiral, a specific isomer or a derivative of a chiral molecule | |||
| Chemical formula | C19H39NO | |||
| SMILES | O1C(CN(CCCCCCCCCCCCC)CC1C)C | |||
| International Chemical Identifier key (InChIKey) | YTOPFCCWCSOHFV-UHFFFAOYSA-N | |||
| International Chemical Identifier (InChI) | InChI=1S/C19H39NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-20-16-18(2)21-19(3)17-20/h18-19H,4-17H2,1-3H3 | |||
| Structure diagram/image available? | Yes | |||
| Molecular mass (g mol-1) | 297.52 | |||
| PIN (Preferred Identification Name) | for major component is (2?,6?)-2,6-dimethyl-4-tridecylmorpholine | |||
| IUPAC name | reaction mixture of 4-alkyl-2,6-dimethylmorpholines, where “alkyl” is mixture of C11–C14 homologues of which 60–70% is tridecyl | |||
| CAS name | tridemorph | |||
| Other status information | OSPAR soc; Chemical subject to PIC regulations | |||
| Herbicide Resistance Classification (HRAC) | Not applicable | |||
| Herbicide Resistance Classification (WSSA) | Not applicable | |||
| Insecticide Resistance Classification (IRAC) | Not applicable | |||
| Fungicide Resistance Classification (FRAC) | 5 | |||
| Examples of recorded resistance | - | |||
| Physical state | Yellow oily liquid | |||
| Related substances & organisms | - | |||
Formulations:
| Property |
Value | |||
| Example manufacturers & suppliers of products using this active now or historically |
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| Example products using this active |
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| UK LERAP status | No UK approval for use or outside scope | |||
| Formulation and application details | Usually supplied as an emulsifiable concentrate. | |||
ENVIRONMENTAL FATE
for tridemorph
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | 1.1 | L3 | Low | |
| Solubility - In organic solvents at 20oC (mg l-1) | Miscible | L3 - Ethanol | - | |
| Miscible | L3 - Acetone | - | ||
| Miscible | L3 - Ethyl acetate | - | ||
| Miscible | L3 - Benzene | - | ||
| Melting point (oC) | Not applicable | L3 | - | |
| Boiling point (oC) | - | - | - | |
| Degradation point (oC) | - | - | - | |
| Flashpoint (oC) | - | - | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | 1.58 X 1004 | Calculated | - |
| Log P | 4.2 | L3 | High | |
| Bulk density (g ml-1)/Specific gravity | 0.86 | L3 | - | |
| Dissociation constant (pKa) at 25oC | 6.5 | L3 | - | |
| Note: Weak acid | ||||
| Vapour pressure at 25oC (mPa) | 12 | L3 | Highly volatile | |
| Henry's law constant at 25oC (Pa m3 mol-1) | 3.20 | L3 | Moderately volatile | |
| Henry's law constant at 20oC (dimensionless) | 4.90 X 10-04 | K3 | Volatile | |
GUS leaching potential index  |
0.32 | Calculated | Low leachability | |
| SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | 7.82 X 10-03 | Calculated | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | Medium | |
| Maximum UV-vis absorption L mol-1 cm-1 | - | - | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Soil degradation (days) (aerobic) | DT50 (typical) | 24 | L3 | Non-persistent |
| DT50 (lab at 20oC) | 35 | L3 | Moderately persistent | |
| DT50 (field) | 24 | L3 | Non-persistent | |
| DT90 (lab at 20oC) | - | - | - | |
| DT90 (field) | - | - | - | |
| Note | Lab studies DT50 range 20-50 days, field studies DT50range 14-34 days | |||
| Plant matrix DT50 (days) | Value | - | - | - |
| Note | - | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | 0.7 | K3 | Fast |
| Note | - | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | 32 | K4 | Moderately persistent |
| Note | - | |||
| Water-sediment DT50 (days) | 60 | Q2 | Moderately fast | |
| Water phase only DT50 (days) | 26 | Q2 | Slow | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | - | L3 | Non-mobile |
| Koc | 6250 | |||
| Notes and range | - | |||
| Freundlich | Kf | - | - | - |
| Kfoc | - | |||
| 1/n | - | |||
| Notes and range | - | |||
| pH sensitivity | - | |||
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF (l kg-1) | 741 | Q2 Estimated | Threshold for concern |
| CT50 (days) | Not available | - | ||
| Mammals - Acute oral LD50 (mg kg-1) | 500 | B5 Rat | Moderate | |
| Mammals - Short term dietary NOEL | (mg kg-1) | 5 | B5 Rat | High |
| (ppm diet) | 50 | - | ||
| Birds - Acute LD50 (mg kg-1) | 1388 | L3 Phasianidae | Moderate | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | 3.4 | L3 Salmonidae | Moderate | |
| Fish - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | 1.3 | L3 Daphnia magna | Moderate | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Non-target plants | - | - | - | |
| - | - | - | ||
| Algae - Acute 72 hour EC50, growth (mg l-1) | 0.28 | L2 Unknown species | Moderate | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | 0.015 | Q2 Unknown species | Moderate | |
| Honeybees | Contact acute 48 hour LD50 (μg bee-1) | - | - | - |
| Oral acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Unknown mode acute 48 hour LD50 (μg bee-1) | 200 | L2 | Low | |
| Earthworms - Acute 14 day LC50 (mg kg-1) | 880 | L3 Eisenia foetida | Moderate | |
| Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms - e.g. Collembola | LR50 / EC50 / NOEC / % Effect | - | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | Harmless | Dose: 300 g ha-1 AA3 Typhlodromus pyri |
- | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | Harmless | Dose: 300 g ha-1 AA3 Cheiracanthium mildei |
- | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
HUMAN HEALTH AND PROTECTION
for tridemorph
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Threshold of Toxicological Concern (Cramer Class) |
High (class III) | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | 500 | B5 Rat | Moderate | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | > 4000 | L3 Rat | - | |
| Mammals - Inhalation LC50 (mg l-1) | 4.5 | L3 Rat, 4 hr | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | 0.016 | L3 | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | - | - | - | |
| Exposure Limits | - | - | - | |
| Exposure Routes | Public | - | ||
| Occupational | - | |||
| European MRLs | Click here for the EU MRL pesticide database | |||
| Drinking Water MAC (μg l-1) | - | - | - | |
Health issues:
| Carcinogen | Mutagen | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
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| Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
- |
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| General human health issues | Moderately toxic May cause dermatitis or conjunctivitis |
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: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found
Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| General |
No information available | |||
| CLP classification 2013 | Health: H302, H315, H332, H360D Environment: H400, H410 |
|||
| EC Risk Classification |
Reproduction risk category 2: R61 Xn - Harmful: R20/22 Xi - Irritant: R38 N - Dangerous for the environment: R50, R53 |
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| EC Safety Classification |
S45, S53, S60, S61 | |||
| WHO Classification | II | - | Moderately hazardous | |
| US EPA Classification (formulation) | No consensus across products or no products available | - | - | |
| UN Number | - | |||
| Waste disposal & packaging |
- | |||
| Language | Name |
| English | tridemorph |
| French | tridemorphe |
| German | Tridemorph |
| Danish | tridemorph |
| Italian | tridemorf |
| Spanish | tridemorf |
| Greek | - |
| Slovenian | tridemorf |
| Polish | tridemorf |
| Swedish | - |
| Hungarian | tridemorf |
| Dutch | tridemorf |
Record last updated: Sunday 20 March 2016
Contact: aeru@herts.ac.uk