Brodifacoum is a second generation rodenticide. It has a low aqueous solubility and a low volatility. It is moderately persistent in both soil and aquatic systems with a low risk of leaching to groundwater. Its toxicity to biodiversity is high to moderate. It is highly toxic to mammals via the oral route.
Data alerts
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate High alert: Persistent; Potential for particle bound transport: High
Ecotoxicity High alert: Birds acute ecotoxicity: High; Fish acute ecotoxicity: High
Human health High alert: Mammals acute toxicity: High; Reproduction/development effects
GENERAL INFORMATION
Description
A coumarin rodenticide used inside buildings
Example pests controlled
Rats; Mice; Gophers
Example applications
House; Commercial properties; Industrial sites
Efficacy & activity
-
Availability status
Current
Introduction & key dates
1978
UK regulatory status
UK COPR regulatory status
Not approved
Date COPR inclusion expires
Expired
UK LERAP status
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
EC Regulation 1107/2009 status
Not approved
Dossier rapporteur/co-rapporteur
Not applicable
Date EC 1107/2009 inclusion expires
Expired
EU Candidate for substitution (CfS)
Not applicable
Listed in EU database
Yes
Approved for use (✓) under EC 1107/2009 in the following EU Member States
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
✓
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
Additional information
Also used in
Australia, USA
Chemical structure
Isomerism
Brodifacoum has two chiral centres. Brodifacoum exists as cis- and trans-isomers,where the cis-isomer is an isomeric mixture of (1R,3S) and (1S,3R) and the transisomer is an isomeric mixture of (1R,3R) and (1S,3S).
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242