(Also known as: toxaphene; polychlorocamphene; chlorocamphene; toxafeen; octachlorocamphene)
SUMMARY
Camphechlor is an obsolete insecticide and acaricide. It has a low aqueous solubility, is quite volatile and moderately mobile. Based on its chemical properties, it has a high risk of leaching to groundwater. It is not expected to be persistent in soil but may be persistent in water systems. Camphechlor is highly toxic to mammals and is likely to bioaccumulate. It is highly toxic to birds and most aquatic organisms.
Data alerts
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate Moderate alert: Drainflow: Moderately mobile; Potential for particle bound transport: Medium
Ecotoxicity High alert: Birds acute ecotoxicity: High; Fish acute ecotoxicity: High; Fish chronic ecotoxicity: High; Daphnia acute ecotoxicity: High; Bees acute contact ecotoxicity: High
Human health High alert: Mammals acute toxicity: High; Carcinogen; Reproduction/development effects
GENERAL INFORMATION
Description
Control of ticks, flas and mange mites
Availability status
Considered obsolete but may be available in some countries; Banned in many countries
A non-systemic contact and stomach insecticide. It acts on the neurons, causing an imbalance in sodium and potassium ions, similar to that of the cyclodiene insecticides.
Molecular targets
-
CAS RN
8001-35-2
EC number
232-283-3
CIPAC number
23
US EPA chemical code
080501
PubChem CID
58167
CLP index number
602-044-00-1
ATCvet Code
-
Therapeutic Class
-
Controlled Drug?
-
Regulation 37/2010 MRL Classification
-
Molecular mass
413.96
PIN (Preferred Identification Name)
-
IUPAC name
reaction mixture of chlorinated camphenes containing 67–69% chlorine
CAS name
2,2,5-endo,6-exo,8,8,9,10-Octachlorobornane
Other status information
Chemical subject to PIC regulations; OSPAR soc; POP - regulated by Stockholm Convention; Severe Marine Pollutant; Rotterdam Convention (Class O); PAN Bad Actor
Relevant Environmental Water Quality Standards
-
Physical state
Yellow to amber waxy solid
Formulations
Property
Product
Manufacturer
Authorisation Route
UK Legal Class
Example products using this active
-
-
-
-
Formulation and application details
Usually formulated as a wettable power, dust or emulsifiable concentrate
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes
-
Data type
Observed in metabolism and farm animal feeding studies
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes
Absorbed by the intact skin and from the gastrointestinal tract
Mammalian dose elimination route and rate
-
-
-
Health issues
Specific human health issues
Carcinogen
Genotoxic
Endocrine disruptor
✓Yes, known to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
;
B0 B = DNA damage/repair (EFSA database) 0 = No data
;
C0 C = Gene mutation (EFSA database) 0 = No data
;
D0 D = Genome mutation (EFSA database) 0 = No data
;
E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
?Possibly, status not identified
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
?Possibly, status not identified
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
?Possibly, status not identified
No data found
General human health issues
IARC group 2B carcinogen Ingestion may be fatal May cause convulsions Potential kidney toxicant May cause allergic bronchopneumonia Endocrine issues - Increase of estrogen-sensitive cells proliferation
Handling issues
Property
Value and interpretation
General
Corrosive Not compatible with strongly alkaline pesticides
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242
Environmental fate
Ecotoxicity
