Olaquindox
Last updated: 30/06/2022
(Also known as: olachindox)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Substance with antimicrobial properties and used as a growth promotor mainly for pigs
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1976, first approval
Pigs, Cattle
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C₁₂H₁₃N₃O₄
CC1=C([N+](=O)C2=CC=CC=C2N1[O-])C(=O)NCCO
No data
TURHTASYUMWZCC-UHFFFAOYSA-N
InChI=1S/C12H13N3O4/c1-8-11(12(17)13-6-7-16)15(19)10-5-3-2-4-9(10)14(8)18/h2-5,16H,6-7H2,1H3,(H,13,17)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
olaquindox
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Antibiotic, Growth promoter, Performance enhancer, Feed additive
Quinolone
98%
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Synthetic
Uncertain but believed to act by suppressing gut bacterial growth
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23696-28-8
245-832-7
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-
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QJ01MQ01
Antiinfectants for systemic use: Antibacterials for systemic use
No
No data
263.25
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N-(2-hydroxyethyl)-3-methyl-4-oxido-1-oxoquinoxalin-1-ium-2-carboxamide
N-(2-hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide
Banned in EU as growth promotor; Evidence of use in third world countries; Not approved as a feed additive in EU
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Pale yellow crystals
None identified
None identified
No UK authorisation for use with animals
Not applicable
Usually supplied as a feed pre-mix
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-
-
-
-
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202
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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-
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-
-
-
-
-
-
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7.41 X 10-03
Calculated
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-2.13
Low
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-
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-
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1.532
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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13.75
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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-
-
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-
-
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7.3
R4 R = Peer reviewed scientific publications 4 = Verified data
Non-persistent
7.3
R4 R = Peer reviewed scientific publications 4 = Verified data
Non-persistent
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-
-
-
-
-
-
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-
DT₅₀ range 5.8-8.8 days
7.35
R4 R = Peer reviewed scientific publications 4 = Verified data
Soil-manure slurry
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-
-
-
-
-
-
-
-
-
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-
-
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Soil adsorption and mobility
1.21
R4 R = Peer reviewed scientific publications 4 = Verified data
Moderately mobile
88
Literature data Kd range 0.69-1.67 mL g⁻¹, Koc range 46-116 mL g⁻¹, soils=4
1.04
R4 R = Peer reviewed scientific publications 4 = Verified data
Moderately mobile
75.6
1.35
Literature data Kf range 0.84-1.20 mL g⁻¹, Kfoc range 56.0-95.5 mL g⁻¹, 1 /n range 1.25-1.49, Soils=4
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1.83
Calculated
Transition state
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-
-
-
-
Known soil and groundwater metabolites
None
3-methylquinoxaline-2-carboxylic acid
MQCA
Animal
-
-
Terrestrial ecotoxicology
1704
Rat
Moderate
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> 1000
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Daphnia magna LOEC
Low
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40
R4 R = Peer reviewed scientific publications 4 = Verified data
Selenastrum capricornutum
Low
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-
-
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-
-
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HUMAN HEALTH AND PROTECTION
High (class III)
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1704
Rat
Moderate
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> 1.75
Rat 4 hr
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Rapidly absorbed, metabolised and mostly excreted in the urine with lesser amounts in faeces and bile
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E2 E = Unspecified genotoxicity type (miscellaneous data source) 2 = Mixed/ambiguous results
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
Genotoxic A rodent tumorigen
Emits toxic vapors of NOx when heated to decomposition
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Not listed (Not listed)
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olaquindox
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Record last updated:
30/06/2022
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242