Deslorelin acetate |
![]() Last updated: 31/08/2023 |
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(Also known as: deslorelin) |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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A veterinary drug used to induce ovulation in mares as part of the artificial insemination process and to stabilize high-risk pregnancies in livestock | |
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Horses, Dogs, Cattle |
Chemical structure |
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Isomeric | |
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C₆₄H₈₃N₁₇O₁₂ | |
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CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7)NC(=O)C8CCC(=O)N8 | |
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CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)[C@@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)C8CCC(=O)N8 | |
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LYCYLGFSIXIXAB-NUZRHMIVSA-N | |
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InChI=1S/C64H83N17O12.C2H4O2/c1-4-68-62(92)53-16-10-24-81(53)63(93)46(15-9-23-69-64(65)66)74-56(86)47(25-35(2)3)75-58(88)49(27-37-30-70-43-13-7-5-11-41(37)43)77-57(87)48(26-36-17-19-40(83)20-18-36)76-61(91)52(33-82)80-59(89)50(28-38-31-71-44-14-8-6-12-42(38)44)78-60(90)51(29-39-32-67-34-72-39)79-55(85)45-21-22-54(84)73-45;1-2(3)4/h5-8,11-14,17-20,30-32,34-35,45-53,70-71,82-83H,4,9-10,15-16,21-29,33H2,1-3H3,(H,67,72)(H,68,92)(H,73,84)(H,74,86)(H,75,88)(H,76,91)(H,77,87)(H,78,90)(H,79,85)(H,80,89)(H4,65,66,69);1H3,(H,3,4)/t45-,46-,47-,48-,49+,50-,51-,52-,53-;/m0./s1 | |
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Yes |
General status |
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Hormone, Fertility drug, Medicinal drug | |
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Hormone | |
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99% | |
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Synthetic | |
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A hormone antagonist | |
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[Gonadotrophin-releasing hormone, agonist] | |
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57773-65-6 | |
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25077533 | |
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QH01CA93 | |
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Systemic hormonal preparations excluding sex hormones & insulins: Pituitary & hypothalamic hormones & analogues | |
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No | |
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Allowed substance (Table 1: Equidae) | |
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1282.45 | |
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl) -1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide | |
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White to off-white powder |
Formulations |
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Ovuplant 2.1mg Implantation Tablets for Mares | Dechra Ltd | EU Mutually recognised procedure | Prescription only medicine to be authorised by a veterinarian (POM-V) | ||||||
Supralorin 4.7mg Implant for Dogs | Virbac SA | EU Centralised procedure | Prescription only medicine to be authorised by a veterinarian (POM-V) | |||||||
Supralorin 9.4mg Implant for Dogs | Virbac SA | EU Centralised procedure | Prescription only medicine to be authorised by a veterinarian (POM-V) | |||||||
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Usually supplied as an injectable solution, in tablet form for oral administration or as implants |
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
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Terrestrial ecotoxicology |
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Aquatic ecotoxicology |
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General |
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May be absorbed through skin | ||||||||||
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Excretion is primarily via the urine. | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Health issues |
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May be harmful if swallowed or absorbed through skin |
Handling issues |
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No information available | |||
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Not listed (Not listed) | |||
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deslorelin acetate | ||
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desloreline | ||
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deslorelina | ||
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Record last updated: | 31/08/2023 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |